Publications by authors named "Irit Huber"

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XPRESSO: Rapid genetic engineering of human pluripotent stem cells for durable overexpression using a modular anti-silencing vector.
Yehuda Wexler, Harel Grinstein, Irit Huber, Shany Glatstein, Matteo Ghiringhelli

Stem Cell Reports· October 2025

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Utilizing Human-Induced Pluripotent Stem Cells to Study Cardiac Electroporation Pulsed-Field Ablation.
Leonid Maizels, Eyal Heller, Michal Landesberg, Shany Glatstein, Irit Huber

Circ Arrhythm Electrophysiol· March 2024

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Utilizing human induced pluripotent stem cells to study atrial arrhythmias in the short QT syndrome.
Assad Shiti, Gil Arbil, Naim Shaheen, Irit Huber, Noga Setter

J Mol Cell Cardiol· October 2023

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Chemogenetics for Gene Therapy Based Targeted Cardiac Electrophysiological Modulation.
Yehuda Wexler, Matteo Ghiringhelli, Naim Shaheen, Shany Glatstein, Irit Huber

Circ Res· March 2023

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shRNAs Targeting a Common Variant Could Alleviate Long-QT1 Disease Severity by Inhibiting a Mutant Allele.
Lucía Cócera-Ortega, Ronald Wilders, Selina C Kamps, Benedetta Fabrizi, Irit Huber

Int J Mol Sci· April 2022

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Characterization of the mechanism by which a nonsense variant in RYR2 leads to disordered calcium handling.
Claire Hopton, Anke J Tijsen, Leonid Maizels, Gil Arbel, Amira Gepstein, Irit Huber

Physiol Rep· April 2022

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Optogenetic Control of Human Induced Pluripotent Stem Cell-Derived Cardiac Tissue Models.
Amit Gruber, Oded Edri, Shany Glatstein, Idit Goldfracht, Irit Huber

J Am Heart Assoc· February 2022

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Optogenetic modulation of cardiac action potential properties may prevent arrhythmogenesis in short and long QT syndromes.
Amit Gruber, Oded Edri, Irit Huber, Gil Arbel, Amira Gepstein

JCI Insight· June 2021

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Using Decellularization/Recellularization Processes to Prepare Liver and Cardiac Engineered Tissues.
Matteo Ghiringhelli, Yousef Abboud, Snizhanna V Chorna, Irit Huber, Gil Arbel

Methods Mol Biol· March 2021

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Engineered heart tissue models from hiPSC-derived cardiomyocytes and cardiac ECM for disease modeling and drug testing applications.
Idit Goldfracht, Yael Efraim, Rami Shinnawi, Ekaterina Kovalev, Irit Huber

Acta Biomater· July 2019

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Modeling Reentry in the Short QT Syndrome With Human-Induced Pluripotent Stem Cell-Derived Cardiac Cell Sheets.
Rami Shinnawi, Naim Shaheen, Irit Huber, Assad Shiti, Gil Arbel

J Am Coll Cardiol· May 2019

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Modeling Peripartum Cardiomyopathy With Human Induced Pluripotent Stem Cells Reveals Distinctive Abnormal Function of Cardiomyocytes.
Nili Naftali-Shani, Natali Molotski, Yael Nevo-Caspi, Michael Arad, Rafael Kuperstein, Irit Huber

Circulation· December 2018

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Human Induced Pluripotent Stem Cell-Derived Cardiac Cell Sheets Expressing Genetically Encoded Voltage Indicator for Pharmacological and Arrhythmia Studies.
Naim Shaheen, Assad Shiti, Irit Huber, Rami Shinnawi, Gil Arbel

Stem Cell Reports· June 2018

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Patient-Specific Drug Screening Using a Human Induced Pluripotent Stem Cell Model of Catecholaminergic Polymorphic Ventricular Tachycardia Type 2.
Leonid Maizels, Irit Huber, Gil Arbel, Anke J Tijsen, Amira Gepstein

Circ Arrhythm Electrophysiol· June 2017

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Monitoring Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Genetically Encoded Calcium and Voltage Fluorescent Reporters.
Rami Shinnawi, Irit Huber, Leonid Maizels, Naim Shaheen, Amira Gepstein

Stem Cell Reports· October 2015

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Modeling of arrhythmogenic right ventricular cardiomyopathy with human induced pluripotent stem cells.
Oren Caspi, Irit Huber, Amira Gepstein, Gil Arbel, Leonid Maizels

Circ Cardiovasc Genet· December 2013

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Derivation and cardiomyocyte differentiation of induced pluripotent stem cells from heart failure patients.
Limor Zwi-Dantsis, Irit Huber, Manhal Habib, Aaron Winterstern, Amira Gepstein

Eur Heart J· June 2013

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Modeling of catecholaminergic polymorphic ventricular tachycardia with patient-specific human-induced pluripotent stem cells.
Ilanit Itzhaki, Leonid Maizels, Irit Huber, Amira Gepstein, Gil Arbel

J Am Coll Cardiol· September 2012

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Calcium handling in human induced pluripotent stem cell derived cardiomyocytes.
Ilanit Itzhaki, Sophia Rapoport, Irit Huber, Itzhak Mizrahi, Limor Zwi-Dantsis

PLoS One· April 2011

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Modelling the long QT syndrome with induced pluripotent stem cells.
Ilanit Itzhaki, Leonid Maizels, Irit Huber, Limor Zwi-Dantsis, Oren Caspi

Nature· March 2011

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Reprogramming of telomeric regions during the generation of human induced pluripotent stem cells and subsequent differentiation into fibroblast-like derivatives.
Shiran Yehezkel, Annie Rebibo-Sabbah, Yardena Segev, Maty Tzukerman, Rony Shaked, Irit Huber

Epigenetics· January 2011

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Methods for human embryonic stem cells derived cardiomyocytes cultivation, genetic manipulation, and transplantation.
Gil Arbel, Oren Caspi, Irit Huber, Amira Gepstein, Michal Weiler-Sagie

Methods Mol Biol· December 2010

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In vivo assessment of the electrophysiological integration and arrhythmogenic risk of myocardial cell transplantation strategies.
Lior Gepstein, Chunhua Ding, Dolkun Rahmutula, Emily E Wilson, Lior Yankelson, Irit Huber

Stem Cells· December 2010

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In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes.
Oren Caspi, Ilanit Itzhaki, Izhak Kehat, Amira Gepstein, Gil Arbel, Irit Huber

Stem Cells Dev· October 2010

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Cardiomyocyte differentiation of human induced pluripotent stem cells.
Limor Zwi, Oren Caspi, Gil Arbel, Irit Huber, Amira Gepstein

Circulation· October 2009

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