Publications by authors named "Irmina Diala"

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PI3K and MAPK Pathways as Targets for Combination with the Pan-HER Irreversible Inhibitor Neratinib in HER2-Positive Breast Cancer and TNBC by Kinome RNAi Screening.
Jangsoon Lee, Huey Liu, Troy Pearson, Toshiaki Iwase, Jon Fuson, Irmina Diala

Biomedicines· June 2021

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Neratinib plus trastuzumab is superior to pertuzumab plus trastuzumab in HER2-positive breast cancer xenograft models.
Jamunarani Veeraraghavan, Carolina Gutierrez, Vidyalakshmi Sethunath, Sepideh Mehravaran, Mario Giuliano, Irmina Diala

NPJ Breast Cancer· May 2021

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Combining Neratinib with CDK4/6, mTOR, and MEK Inhibitors in Models of HER2-positive Cancer.
Ming Zhao, Stephen Scott, Kurt W Evans, Erkan Yuca, Turcin Saridogan, Irmina Diala

Clin Cancer Res· March 2021

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Comparative analysis of drug response and gene profiling of HER2-targeted tyrosine kinase inhibitors.
Neil T Conlon, Jeffrey J Kooijman, Suzanne J C van Gerwen, Winfried R Mulder, Guido J R Zaman, Irmina Diala

Br J Cancer· March 2021

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Telomerase inhibition, telomere attrition and proliferation arrest of cancer cells induced by phosphorothioate ASO-NLS conjugates targeting hTERC and siRNAs targeting hTERT.
Irmina Diala, Yasuo Shiohama, Takashi Fujita, Yojiro Kotake, Constantinos Demonacos

Nucleosides Nucleotides Nucleic Acids· September 2020

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Use of Patient-Derived Tumor Organotypic Spheroids to Identify Combination Therapies for Mutant Non-Small Cell Lung Cancer.
Elena Ivanova, Mari Kuraguchi, Man Xu, Andrew J Portell, Luke Taus, Irmina Diala

Clin Cancer Res· May 2020

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HER2-Mediated Internalization of Cytotoxic Agents in Amplified or Mutant Lung Cancers.
Bob T Li, Flavia Michelini, Sandra Misale, Emiliano Cocco, Laura Baldino, Irmina Diala

Cancer Discov· May 2020

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Palbociclib augments Neratinib killing of tumor cells that is further enhanced by HDAC inhibition.
Laurence Booth, Jane L Roberts, Rumeesa Rais, Richard E Cutler, Irmina Diala

Cancer Biol Ther· April 2020

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The calcium-sensing receptor: A novel target for treatment and prophylaxis of neratinib-induced diarrhea.
Taras Lysyy, Alshad S Lalani, Elizabeth A Olek, Irmina Diala, John P Geibel

Pharmacol Res Perspect· October 2019

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Neoadjuvant neratinib promotes ferroptosis and inhibits brain metastasis in a novel syngeneic model of spontaneous HER2 breast cancer metastasis.
Aadya Nagpal, Richard P Redvers, Xiawei Ling, Scott Ayton, Miriam Fuentes, Irmina Diala

Breast Cancer Res· August 2019

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Neratinib augments the lethality of [regorafenib + sildenafil].
Laurence Booth, Jane L Roberts, Rumeesa Rais, Richard E Cutler, Irmina Diala

J Cell Physiol· April 2019

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Development of a membrane-based microwave-mediated electrochemical ELISA method for TNF-α detection in patients with periodontitis.
Irmina Diala, Shinobu Sato, Michihiko Usui, Keisuke Nakashima, Tatsuji Nishihara

Anal Sci· September 2014

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Telomere protection and TRF2 expression are enhanced by the canonical Wnt signalling pathway.
Irmina Diala, Nicole Wagner, Frédérique Magdinier, Marina Shkreli, Maria Sirakov

EMBO Rep· April 2013

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Suppression of bcr-abl mRNA by chemically modified siRNA.
Satoshi Murao, Irmina Diala, Masayuki Fujii

Nucleic Acids Symp Ser (Oxf)· November 2010

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Antisense inhibition of human telomerase by phosphorothioate oligonucleotide-peptide conjugates.
Irmina Diala, Satoshi Murao, Masayuki Fujii

Nucleic Acids Symp Ser (Oxf)· November 2010

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Synthesis of phosphorothioate oligonucleotide-peptide conjugates by solid phase fragment condensation.
Irmina Diala, Akira Osada, Shinji Maruoka, Takashi Imanisi, Satoshi Murao

Bioorg Med Chem Lett· December 2007

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