Publications by authors named "Iryna Prots"

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Cytotoxicity testing of dental materials: Establishment of a 3D-printed dentin barrier culture system.
Ella Ohlsson, Sandra Pohl, Iryna Prots, Carola Bolay, Kerstin M Galler

Dent Mater· December 2025

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Deciphering brain organoid heterogeneity by identifying key quality determinants.
Tom Boerstler, Daniil Kachkin, Elizaveta Gerasimova, Naime Zagha, Federica Furlanetto, Iryna Prots

Commun Biol· October 2025

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TNF-α disrupts the malate-aspartate shuttle, driving metabolic rewiring in iPSC-derived enteric neural lineages from Parkinson's Disease patients.
Bruno Ghirotto, Luís Eduardo Gonçalves, Vivien Ruder, Christina James, Elizaveta Gerasimova, Iryna Prots

bioRxiv· March 2025

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Novel co-culture model of T cells and midbrain organoids for investigating neurodegeneration in Parkinson's disease.
Elizaveta Gerasimova, Amke C Beenen, Daniil Kachkin, Martin Regensburger, Sebastian Zundler, Iryna Prots

NPJ Parkinsons Dis· February 2025

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NPT100-18A rescues mitochondrial oxidative stress and neuronal degeneration in human iPSC-based Parkinson's model.
Julian E Alecu, Veronika Sigutova, Razvan-Marius Brazdis, Sandra Lörentz, Marios Evangelos Bogiongko, Iryna Prots

BMC Neurosci· January 2025

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Alpha-synuclein fine-tunes neuronal response to pro-inflammatory cytokines.
Veronika Sigutova, Wei Xiang, Martin Regensburger, Beate Winner, Iryna Prots

Brain Behav Immun· November 2024

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An Enhanced Retroviral Vector for Efficient Genetic Manipulation and Selection in Mammalian Cells.
Jana Triller, Iryna Prots, Hans-Martin Jäck, Jürgen Wittmann

Biomolecules· September 2024

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IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells.
Karen Anne-Marie Ullrich, Julia Derdau, Carsten Baltes, Alice Battistella, Gonzalo Rosso, Iryna Prots

Gut· November 2023

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Translocation of Distinct Alpha Synuclein Species from the Nucleus to Neuronal Processes during Neuronal Differentiation.
Katharina Pieger, Verena Schmitt, Carina Gauer, Nadja Gießl, Iryna Prots

Biomolecules· August 2022

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The Quest for Anti-α-Synuclein Antibody Specificity-Lessons Learnt From Flow Cytometry Analysis.
Lukas Leupold, Veronika Sigutova, Elizaveta Gerasimova, Martin Regensburger, Sebastian Zundler, Iryna Prots

Front Neurol· July 2022

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Interaction of Alpha Synuclein and Microtubule Organization Is Linked to Impaired Neuritic Integrity in Parkinson's Patient-Derived Neuronal Cells.
Lukas Seebauer, Yanni Schneider, Alice Drobny, Sonja Plötz, Tomas Koudelka, Iryna Prots

Int J Mol Sci· February 2022

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Axon-Specific Mitochondrial Pathology in SPG11 Alpha Motor Neurons.
Fabian Güner, Tatyana Pozner, Florian Krach, Iryna Prots, Sandra Loskarn

Front Neurosci· July 2021

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Unique signatures of stress-induced senescent human astrocytes.
Katrin Simmnacher, Florian Krach, Yanni Schneider, Julian E Alecu, Lena Mautner, Iryna Prots

Exp Neurol· December 2020

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Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson's disease.
Razvan-Marius Brazdis, Julian E Alecu, Daniel Marsch, Annika Dahms, Katrin Simmnacher, Iryna Prots

Hum Mol Genet· May 2020

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Author Correction: A monocyte gene expression signature in the early clinical course of Parkinson's disease.
Johannes C M Schlachetzki, Iryna Prots, Jenhan Tao, Hyun B Chun, Kaoru Saijo

Sci Rep· April 2020

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Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease.
Annika Sommer, Franz Marxreiter, Florian Krach, Tanja Fadler, Janina Grosch, Iryna Prots

Cell Stem Cell· June 2019

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Th17 cells: a promising therapeutic target for Parkinson's disease?
Iryna Prots, Beate Winner

Expert Opin Ther Targets· April 2019

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Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease.
Annika Sommer, Franz Marxreiter, Florian Krach, Tanja Fadler, Janina Grosch, Iryna Prots

Cell Stem Cell· July 2018

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α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies.
Iryna Prots, Janina Grosch, Razvan-Marius Brazdis, Katrin Simmnacher, Vanesa Veber

Proc Natl Acad Sci U S A· July 2018

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A monocyte gene expression signature in the early clinical course of Parkinson's disease.
Johannes C M Schlachetzki, Iryna Prots, Jenhan Tao, Hyun B Chun, Kaoru Saijo

Sci Rep· July 2018

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Impact of Swiprosin-1/Efhd2 on Adult Hippocampal Neurogenesis.
Martin Regensburger, Iryna Prots, Dorothea Reimer, Sebastian Brachs, Sandra Loskarn

Stem Cell Reports· February 2018

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The Trojan horse - neuroinflammatory impact of T cells in neurodegenerative diseases.
Annika Sommer, Beate Winner, Iryna Prots

Mol Neurodegener· October 2017

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Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress.
Stefanie Menges, Georgia Minakaki, Patrick M Schaefer, Holger Meixner, Iryna Prots

Sci Rep· February 2017

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Infiltrating T lymphocytes reduce myeloid phagocytosis activity in synucleinopathy model.
Annika Sommer, Tanja Fadler, Eva Dorfmeister, Anna-Carin Hoffmann, Wei Xiang, Iryna Prots

J Neuroinflammation· June 2016

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GSK3ß-dependent dysregulation of neurodevelopment in SPG11-patient induced pluripotent stem cell model.
Himanshu K Mishra, Iryna Prots, Steven Havlicek, Zacharias Kohl, Francesc Perez-Branguli

Ann Neurol· May 2016

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