Publications by authors named "Isaac Chan"

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A comprehensive evaluation of de novo metastatic breast cancer trends by subtype from the Dallas Metastatic Cancer Study.
Hannah L Chang, Meng Cao, Mir Lim, Anna Moscowitz, Ang Gao, Isaac S Chan

Commun Med (Lond)· August 2025

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The MBCRC Advocate Researcher Program (MARP): connecting advocates and researchers as collaborative partners in cancer research.
Hillary S Andrews, Igor L Bado, Amy Beumer, Isaac S Chan, Janice Cowden

NPJ Breast Cancer· June 2025

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A new Neu-a syngeneic model of spontaneously metastatic HER2-positive breast cancer.
Aaron G Baugh, Edgar Gonzalez, Valerie H Narumi, Jesse Kreger, Yingtong Liu, Isaac Chan

Clin Exp Metastasis· October 2024

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Evaluation of markers of immunity in different metastatic immune microenvironments suggests more suppression within breast to liver metastases in breast cancer.
Robert Hsu, Batul Al-Zubeidy, Daniel Flores, Ari Nazarian, Aaron Baugh, Isaac S Chan

Breast Cancer Res Treat· July 2024

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A comprehensive single-cell breast tumor atlas defines epithelial and immune heterogeneity and interactions predicting anti-PD-1 therapy response.
Lily Xu, Kaitlyn Saunders, Shao-Po Huang, Hildur Knutsdottir, Kenneth Martinez-Algarin, Isaac S Chan

Cell Rep Med· May 2024

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Digital droplet PCR analysis of organoids generated from mouse mammary tumors demonstrates proof-of-concept capture of tumor heterogeneity.
Katherine E Lake, Megan M Colonnetta, Clayton A Smith, Kaitlyn Saunders, Kenneth Martinez-Algarin, Isaac S Chan

Front Cell Dev Biol· May 2024

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The exon-junction complex helicase eIF4A3 holds therapeutic potential in acute myeloid leukemia.
Sophia Miliara, Elisabetta Cozzi, Xiangfu Zhong, Isaac Chan, Karl Ekwall

Leukemia· March 2024

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Mimicking the breast metastatic microenvironment: characterization of a novel syngeneic model of HER2 breast cancer.
Aaron G Baugh, Edgar Gonzalez, Valerie H Narumi, Jesse Kreger, Yingtong Liu, Isaac Chan

bioRxiv· January 2024

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Antibody-drug conjugates in breast cancer: overcoming resistance and boosting immune response.
Hannah L Chang, Blake Schwettmann, Heather L McArthur, Isaac S Chan

J Clin Invest· September 2023

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Technology, Training, and Task Shifting at the World's Largest Mass Gathering in 2025: An Opportunity for Antibiotic Stewardship in India.
Isaac H Y Chan, Miriam Gofine, Shitij Arora, Ahmed Shaikh, Satchit Balsari

JMIR Public Health Surveill· March 2023

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Organoid generation from mouse mammary tumors captures the genetic heterogeneity of clinically relevant copy number alterations.
Katherine E Lake, Megan M Colonetta, Clayton A Smith, Kenneth Martinez-Algarin, Kaitlyn Saunders, Isaac S Chan

bioRxiv· January 2023

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Generating and Imaging Mouse and Human Epithelial Organoids from Normal and Tumor Mammary Tissue Without Passaging.
Serena L Cornelius, Megan M Colonnetta, Katherine E Lake, Clayton A Smith, Yu-An Zhang, Isaac S Chan

J Vis Exp· November 2022

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Increasing the field-of-view in oblique plane microscopy via optical tiling.
Bingying Chen, Bo-Jui Chang, Felix Y Zhou, Stephan Daetwyler, Etai Sapoznik, Isaac S Chan

Biomed Opt Express· November 2022

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Olaparib Use in Patients With Metastatic Breast Cancer Harboring Somatic BRCA1/2 Mutations or Mutations in Non-BRCA1/2, DNA Damage Repair Genes.
Elaine M Walsh, Neha Mangini, John Fetting, Deborah Armstrong, Isaac S Chan

Clin Breast Cancer· June 2022

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Improving the odds together: a framework for breast cancer research scientists to include patient advocates in their research.
Hillary Stires, Igor Bado, Thelma Brown, Martha Carlson, Isaac S Chan

NPJ Breast Cancer· June 2022

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Organoid Co-culture Methods to Capture Cancer Cell-Natural Killer Cell Interactions.
Isaac S Chan, Andrew J Ewald

Methods Mol Biol· April 2022

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The changing role of natural killer cells in cancer metastasis.
Isaac S Chan, Andrew J Ewald

J Clin Invest· March 2022

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Population-based targeted sequencing of 54 candidate genes identifies as a susceptibility gene for high-grade serous ovarian cancer.
Honglin Song, Ed M Dicks, Jonathan Tyrer, Maria Intermaggio, Georgia Chenevix-Trench, Isaac Chan

J Med Genet· May 2021

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Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level.
Helen R Clark, Connor McKenney, Nathan M Livingston, Ariel Gershman, Seema Sajjan, Isaac S Chan

Nat Commun· March 2021

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Rare Germline Genetic Variants and the Risks of Epithelial Ovarian Cancer.
Marina Pavanello, Isaac Hy Chan, Amir Ariff, Paul Dp Pharoah, Simon A Gayther

Cancers (Basel)· October 2020

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Cancer cells educate natural killer cells to a metastasis-promoting cell state.
Isaac S Chan, Hildur Knútsdóttir, Gayathri Ramakrishnan, Veena Padmanaban, Manisha Warrier

J Cell Biol· September 2020

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Diabetes as a risk factor for incident peripheral arterial disease in women compared to men: a systematic review and meta-analysis.
Alyssa Z Chase-Vilchez, Isaac H Y Chan, Sanne A E Peters, Mark Woodward

Cardiovasc Diabetol· September 2020

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Impact of the Current US Preventive Services Task Force Recommendations for Cervical Cancer Screening in Young Women 21 to 29 Years Old.
C Paul Morris, Sayanan Chowsilpa, Sara Mustafa, Isaac Chan, Daniel Miller

Am J Clin Pathol· May 2020

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Immunotherapy for Merkel cell carcinoma: a turning point in patient care.
Isaac S Chan, Shailender Bhatia, Howard L Kaufman, Evan J Lipson

J Immunother Cancer· March 2018

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Post-migration follow-up of migrants identified to be at increased risk of developing tuberculosis at pre-migration screening: a systematic review and meta-analysis.
Isaac H Y Chan, Nishta Kaushik, Claudia C Dobler

Lancet Infect Dis· July 2017

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