Publications by authors named "Isaac P Forquer"

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Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria.
Lisa Frueh, Yuexin Li, Michael W Mather, Qigui Li, Sovitj Pou, Isaac P Forquer

ACS Infect Dis· October 2017

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Atovaquone and ELQ-300 Combination Therapy as a Novel Dual-Site Cytochrome bc1 Inhibition Strategy for Malaria.
Allison M Stickles, Martin J Smilkstein, Joanne M Morrisey, Yuexin Li, Isaac P Forquer

Antimicrob Agents Chemother· August 2016

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Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone.
Lauren A Lawres, Aprajita Garg, Vidya Kumar, Igor Bruzual, Isaac P Forquer

J Exp Med· June 2016

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ELQ-300 prodrugs for enhanced delivery and single-dose cure of malaria.
Galen P Miley, Sovitj Pou, Rolf Winter, Aaron Nilsen, Yuexin Li, Isaac P Forquer

Antimicrob Agents Chemother· September 2015

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Inhibition of cytochrome bc1 as a strategy for single-dose, multi-stage antimalarial therapy.
Allison M Stickles, Li-Min Ting, Joanne M Morrisey, Yuexin Li, Michael W Mather, Isaac P Forquer

Am J Trop Med Hyg· June 2015

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Subtle changes in endochin-like quinolone structure alter the site of inhibition within the cytochrome bc1 complex of Plasmodium falciparum.
Allison M Stickles, Mariana Justino de Almeida, Joanne M Morrisey, Kayla A Sheridan, Isaac P Forquer

Antimicrob Agents Chemother· April 2015

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Discovery, synthesis, and optimization of antimalarial 4(1H)-quinolone-3-diarylethers.
Aaron Nilsen, Galen P Miley, Isaac P Forquer, Michael W Mather, Kasiram Katneni

J Med Chem· May 2014

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Quinolone-3-diarylethers: a new class of antimalarial drug.
Aaron Nilsen, Alexis N LaCrue, Karen L White, Isaac P Forquer, Richard M Cross

Sci Transl Med· March 2013

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