Publications by authors named "Isaac P Witte"

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Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase.
Isaac P Witte, George D Lampe, Simon Eitzinger, Shannon M Miller, Kiara N Berríos

Science· May 2025

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Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors.
Jessie R Davis, Xiao Wang, Isaac P Witte, Tony P Huang, Jonathan M Levy

Nat Biomed Eng· November 2022

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Publisher Correction: Efficient in vivo base editing via single adenoassociated viruses with size-optimized genomes encoding compact adenine base editors.
Jessie R Davis, Xiao Wang, Isaac P Witte, Tony P Huang, Jonathan M Levy

Nat Biomed Eng· November 2022

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Site-Specific Lipidation Enhances IFITM3 Membrane Interactions and Antiviral Activity.
Emma H Garst, Hwayoung Lee, Tandrila Das, Shibani Bhattacharya, Avital Percher, Isaac P Witte

ACS Chem Biol· May 2021

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A scoutRNA Is Required for Some Type V CRISPR-Cas Systems.
Lucas B Harrington, Enbo Ma, Janice S Chen, Isaac P Witte, Dov Gertz

Mol Cell· August 2020

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CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks.
Joshua C Cofsky, Deepti Karandur, Carolyn J Huang, Isaac P Witte, John Kuriyan

Elife· June 2020

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Programmed DNA destruction by miniature CRISPR-Cas14 enzymes.
Lucas B Harrington, David Burstein, Janice S Chen, David Paez-Espino, Enbo Ma, Isaac P Witte

Science· November 2018

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