Publications by authors named "Isabel English"

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The Prolyl Isomerase PIN1 Affects Fibroblast Differentiation States and Cross-talk in Pancreatic Cancer.
Chloe L Bowman, Colin J Daniel, Eric J Carlson, Vidhi M Shah, Amy S Farrell, Isabel A English

Cancer Res· December 2025

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Nuclear cGAS mediated replication stress and mitotic catastrophe can overcome gemcitabine resistance.
Soon Young Park, Kang Jin Jeong, Alfonso Poire, Bo Young Jeong, Yuhan Sheng, Isabel A English

Cancer Lett· September 2025

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Myc and Kras cooperate in adult acinar cells to drive phenotypic heterogeneity, metastasis, and therapeutic resistance in a novel pancreatic cancer mouse model.
Isabel A English, Patrick J Worth, Kevin Alexander MacPherson-Hawthorne, Macarena Vergara, Katherine Pelz

bioRxiv· July 2025

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Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancer.
Jason M Link, Jennifer R Eng, Carl Pelz, Kevin MacPherson-Hawthorne, Patrick J Worth, Isabel A English

Nat Cancer· January 2025

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KRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development.
Samantha L Tinsley, Ella Rose D Chianis, Rebecca A Shelley, Gaganpreet K Mall, Alisha Dhiman, Isabel A English

Oncogene· December 2024

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Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.
Daniel Bottomly, Nicola Long, Anna Reister Schultz, Stephen E Kurtz, Cristina E Tognon, Isabel English

Cancer Cell· August 2022

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Select Stabilization of a Tumor-Suppressive PP2A Heterotrimer.
Vidhi M Shah, Isabel A English, Rosalie C Sears

Trends Pharmacol Sci· September 2020

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Deconstructing Pancreatic Adenocarcinoma by Targeting the Conductor, MYC.
Isabel A English, Rosalie C Sears

Cancer Discov· April 2020

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Correction: FGF2-FGFR1 signaling regulates release of leukemia-protective exosomes from bone marrow stromal cells.
Nathalie Javidi-Sharifi, Jacqueline Martinez, Isabel English, Sunil K Joshi, Renata Scopim-Ribeiro

Elife· March 2019

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FGF2-FGFR1 signaling regulates release of Leukemia-Protective exosomes from bone marrow stromal cells.
Nathalie Javidi-Sharifi, Jacqueline Martinez, Isabel English, Sunil K Joshi, Renata Scopim-Ribeiro

Elife· February 2019

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Functional genomic landscape of acute myeloid leukaemia.
Jeffrey W Tyner, Cristina E Tognon, Daniel Bottomly, Beth Wilmot, Stephen E Kurtz, Isabel English

Nature· October 2018

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Molecularly targeted drug combinations demonstrate selective effectiveness for myeloid- and lymphoid-derived hematologic malignancies.
Stephen E Kurtz, Christopher A Eide, Andy Kaempf, Vishesh Khanna, Samantha L Savage, Isabel English

Proc Natl Acad Sci U S A· September 2017

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FGF2 from Marrow Microenvironment Promotes Resistance to FLT3 Inhibitors in Acute Myeloid Leukemia.
Elie Traer, Jacqueline Martinez, Nathalie Javidi-Sharifi, Anupriya Agarwal, Jennifer Dunlap, Isabel English

Cancer Res· November 2016

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Sympathetic Innervation Promotes Arterial Fate by Enhancing Endothelial ERK Activity.
Luc Pardanaud, Laurence Pibouin-Fragner, Alexandre Dubrac, Thomas Mathivet, Isabel English

Circ Res· August 2016

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Ponatinib overcomes FGF2-mediated resistance in CML patients without kinase domain mutations.
Elie Traer, Nathalie Javidi-Sharifi, Anupriya Agarwal, Jennifer Dunlap, Isabel English

Blood· March 2014

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