Publications by authors named "Isabel Espadas"

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Enhanced non-enzymatic HS generation extends lifespan and healthspan in male mice.
María Ángeles Cáliz-Molina, Raúl López-Fernández-Sobrino, Inmaculada Pino-Pérez, Concepción Panadero-Morón, María Del Carmen Vilches-Pérez, Isabel Espadas

Cell Metab· December 2025

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lncRNA ADEPTR loss-of-function elicits sex-specific behavioral and spine deficits.
Kaushik Chanda, Jackson P Carter, Hirofumi Nishizono, Bindu L Raveendra, Alicia Brantley, Isabel Espadas

iScience· August 2025

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Defective Olfactomedin-2 connects adipocyte dysfunction to obesity.
Aina Lluch, Jèssica Latorre, Isabel Espadas, Núria Oliveras-Cañellas, José M Moreno-Navarrete

Nat Commun· August 2025

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Author Correction: Metabolic reprogramming by Acly inhibition using SB-204990 alters glucoregulation and modulates molecular mechanisms associated with aging.
Alejandro Sola-García, María Ángeles Cáliz-Molina, Isabel Espadas, Michael Petr, Concepción Panadero-Morón

Commun Biol· February 2025

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A novel long non-coding RNA connects obesity to impaired adipocyte function.
Aina Lluch, Jèssica Latorre, Núria Oliveras-Cañellas, Ana Fernández-Sánchez, José M Moreno-Navarrete, Isabel Espadas

Mol Metab· December 2024

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Hydroxycitrate delays early mortality in mice and promotes muscle regeneration while inducing a rich hepatic energetic status.
Isabel Espadas, María Ángeles Cáliz-Molina, Raúl López-Fernández-Sobrino, Concepción Panadero-Morón, Alejandro Sola-García

Aging Cell· September 2024

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Synaptically-targeted long non-coding RNA SLAMR promotes structural plasticity by increasing translation and CaMKII activity.
Isabel Espadas, Jenna L Wingfield, Yoshihisa Nakahata, Kaushik Chanda, Eddie Grinman

Nat Commun· March 2024

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Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence.
Aina Lluch, Jessica Latorre, Angela Serena-Maione, Isabel Espadas, Estefanía Caballano-Infantes

Nat Commun· August 2023

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Metabolic reprogramming by Acly inhibition using SB-204990 alters glucoregulation and modulates molecular mechanisms associated with aging.
Alejandro Sola-García, María Ángeles Cáliz-Molina, Isabel Espadas, Michael Petr, Concepción Panadero-Morón

Commun Biol· March 2023

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, a synaptically targeted lncRNA, facilitates the consolidation of contextual fear memory.
Isabel Espadas, Jenna Wingfield, Eddie Grinman, Ilika Ghosh, Kaushik Chanda

Res Sq· March 2023

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Molecular motor KIF3B in the prelimbic cortex constrains the consolidation of contextual fear memory.
Nadine F Joseph, Aya Zucca, Jenna L Wingfield, Isabel Espadas, Damon Page

Mol Brain· November 2021

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Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation.
Supriya Swarnkar, Yosef Avchalumov, Isabel Espadas, Eddie Grinman, Xin-An Liu

Cell Rep· July 2021

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Activity-regulated synaptic targeting of lncRNA ADEPTR mediates structural plasticity by localizing Sptn1 and AnkB in dendrites.
Eddie Grinman, Yoshihisa Nakahata, Yosef Avchalumov, Isabel Espadas, Supriya Swarnkar

Sci Adv· April 2021

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Dopamine D2R is Required for Hippocampal-dependent Memory and Plasticity at the CA3-CA1 Synapse.
Isabel Espadas, Oscar Ortiz, Patricia García-Sanz, Adrián Sanz-Magro, Samuel Alberquilla

Cereb Cortex· March 2021

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Beneficial effects of the phytocannabinoid Δ-THCV in L-DOPA-induced dyskinesia in Parkinson's disease.
Isabel Espadas, Ettel Keifman, Cristina Palomo-Garo, Sonia Burgaz, Concepción García

Neurobiol Dis· July 2020

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Emerging roles for long noncoding RNAs in learning, memory and associated disorders.
Eddie Grinman, Isabel Espadas, Sathyanarayanan V Puthanveettil

Neurobiol Learn Mem· September 2019

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N370S-GBA1 mutation causes lysosomal cholesterol accumulation in Parkinson's disease.
Patricia García-Sanz, Lorena Orgaz, Guillermo Bueno-Gil, Isabel Espadas, Eva Rodríguez-Traver

Mov Disord· October 2017

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Nitric oxide synthase inhibition decreases l-DOPA-induced dyskinesia and the expression of striatal molecular markers in Pitx3(-/-) aphakia mice.
Oscar Solís, Isabel Espadas, Elaine A Del-Bel, Rosario Moratalla

Neurobiol Dis· January 2015

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Methamphetamine causes degeneration of dopamine cell bodies and terminals of the nigrostriatal pathway evidenced by silver staining.
Sara Ares-Santos, Noelia Granado, Isabel Espadas, Ricardo Martinez-Murillo, Rosario Moratalla

Neuropsychopharmacology· April 2014

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L-DOPA-induced increase in TH-immunoreactive striatal neurons in parkinsonian mice: insights into regulation and function.
Isabel Espadas, Sanja Darmopil, Eva Vergaño-Vera, Oskar Ortiz, Idaira Oliva

Neurobiol Dis· December 2012

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Involvement of cannabinoid CB1 receptor in associative learning and in hippocampal CA3-CA1 synaptic plasticity.
Noelia Madroñal, Agnès Gruart, Olga Valverde, Isabel Espadas, Rosario Moratalla

Cereb Cortex· March 2012

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Associative learning and CA3-CA1 synaptic plasticity are impaired in D1R null, Drd1a-/- mice and in hippocampal siRNA silenced Drd1a mice.
Oskar Ortiz, José María Delgado-García, Isabel Espadas, Amine Bahí, Ramón Trullas

J Neurosci· September 2010

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