Publications by authors named "Isabel Freund"

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Bacterial tRNA 2'-O-methylation is dynamically regulated under stress conditions and modulates innate immune response.
Adeline Galvanin, Lea-Marie Vogt, Antonia Grober, Isabel Freund, Lilia Ayadi

Nucleic Acids Res· December 2020

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Fractionation-Dependent Radiosensitization by Molecular Targeting of Nek1.
Isabel Freund, Stephanie Hehlgans, Daniel Martin, Michael Ensminger, Emmanouil Fokas

Cells· May 2020

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Crucial Role of Nucleic Acid Sensing via Endosomal Toll-Like Receptors for the Defense of and .
Anna Hafner, Ulrike Kolbe, Isabel Freund, Virginia Castiglia, Pavel Kovarik

Front Immunol· January 2020

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2'--methylation within prokaryotic and eukaryotic tRNA inhibits innate immune activation by endosomal Toll-like receptors but does not affect recognition of whole organisms.
Isabel Freund, Daniel K Buhl, Sébastien Boutin, Annika Kotter, Florian Pichot

RNA· July 2019

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RNA Modifications Modulate Activation of Innate Toll-Like Receptors.
Isabel Freund, Tatjana Eigenbrod, Mark Helm, Alexander H Dalpke

Genes (Basel)· January 2019

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Double methylation of tRNA-U54 to 2'-O-methylthymidine (Tm) synergistically decreases immune response by Toll-like receptor 7.
Patrick Keller, Isabel Freund, Virginie Marchand, Guillaume Bec, Raven Huang

Nucleic Acids Res· October 2018

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Identification of an optimized 2'--methylated trinucleotide RNA motif inhibiting Toll-like receptors 7 and 8.
Felix C F Schmitt, Isabel Freund, Markus A Weigand, Mark Helm, Alexander H Dalpke

RNA· September 2017

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Bioconjugation of Small Molecules to RNA Impedes Its Recognition by Toll-Like Receptor 7.
Isabell Hellmuth, Isabel Freund, Janine Schlöder, Salifu Seidu-Larry, Kathrin Thüring

Front Immunol· March 2017

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Next-Generation Sequencing-Based RiboMethSeq  Protocol for Analysis of tRNA 2'-O-Methylation.
Virginie Marchand, Florian Pichot, Kathrin Thüring, Lilia Ayadi, Isabel Freund

Biomolecules· February 2017

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