Publications by authors named "Isabel Lea"

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Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame.
Susan J Borghoff, Sarah S Cohen, Xiaohui Jiang, Isabel A Lea, William D Klaren

Food Chem Toxicol· February 2023

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Assessment of the applicability of the threshold of toxicological concern for per- and polyfluoroalkyl substances.
Isabel A Lea, Ly Ly Pham, Todor Antonijevic, Chad Thompson, Susan J Borghoff

Regul Toxicol Pharmacol· August 2022

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Overall lack of genotoxic activity among five common low- and no-calorie sweeteners: A contemporary review of the collective evidence.
Isabel A Lea, Grace A Chappell, Daniele S Wikoff

Mutat Res Genet Toxicol Environ Mutagen· September 2021

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Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development.
Christine M Palermo, Jennifer E Foreman, Daniele S Wikoff, Isabel Lea

Curr Res Toxicol· July 2021

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RE: Response to the Office of Environmental Health Hazard Assessment on comments related to Gentry et al. (2021).
Robinan Gentry, Joseph Rodricks, Harvey Clewell, Tracy Greene, Grace Chappell, Isabel Lea

Food Chem Toxicol· June 2021

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Integration of evidence to evaluate the potential for neurobehavioral effects following exposure to USFDA-approved food colors.
Robinan Gentry, Tracy Greene, Grace Chappell, Isabel Lea, Susan Borghoff

Food Chem Toxicol· May 2021

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An integrated chemical environment with tools for chemical safety testing.
Shannon Bell, Jaleh Abedini, Patricia Ceger, Xiaoqing Chang, Bethany Cook, Isabel Lea

Toxicol In Vitro· September 2020

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The TGx-28.65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures.
Marcus A Jackson, Longlong Yang, Isabel Lea, Asif Rashid, Byron Kuo

Environ Mol Mutagen· August 2017

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CEBS: a comprehensive annotated database of toxicological data.
Isabel A Lea, Hui Gong, Anand Paleja, Asif Rashid, Jennifer Fostel

Nucleic Acids Res· January 2017

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Mutation spectra of Kras and Tp53 in urethral and lung neoplasms in B6C3F1 mice treated with 3,3',4,4'-tetrachloroazobenzene.
Sachin Bhusari, David E Malarkey, Hue-Hua Hong, Yu Wang, Tiwanda Masinde, Isabel A Lea

Toxicol Pathol· December 2014

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Characterizing and predicting carcinogenicity and mode of action using conventional and toxicogenomics methods.
Michael D Waters, Marcus Jackson, Isabel Lea

Mutat Res· December 2010

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Genetic pathways to colorectal cancer.
Isabel A Lea, Marcus A Jackson, June K Dunnick

Mutat Res· November 2009

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Genetic alterations in cancer knowledge system: analysis of gene mutations in mouse and human liver and lung tumors.
Marcus A Jackson, Isabel Lea, Asif Rashid, Shyamal D Peddada, June K Dunnick

Toxicol Sci· April 2006

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Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella.
Isabel A Lea, Esther E Widgren, Michael G O'Rand

Reprod Biol Endocrinol· July 2004

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Analysis of recombinant mouse zona pellucida protein 2 (ZP2) constructs for immunocontraception.
Isabel A Lea, Esther E Widgren, Michael G O'Rand

Vaccine· February 2002

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