Publications by authors named "Isabel Lema"

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Visual Function in Alzheimer's Disease: Current Understanding and Potential Mechanisms Behind Visual Impairment.
Tania Alvite-Piñeiro, Maite López-López, Uxía Regueiro, Juan Manuel Pías-Peleteiro, Tomás Sobrino, Isabel Lema

J Clin Med· August 2025

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Serum levels of autotaxin reveal its role as a novel biomarker of migraine.
Alberto Ouro, Mónica Castro-Mosquera, Mariña Rodríguez-Arrizabalaga, Manuel Debasa-Mouce, Daniel Romaus-Sanjurjo, Isabel Lema

Headache· June 2025

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Tear Proteomic Analysis From Offspring of Keratoconus Patients: New Insights Into Corneal Biomechanical Weakness and Disease Risk Stages.
Maite López-López, Uxía Regueiro, Susana Bravo, Carmen Pena, Yaiza Pastoriza, Isabel Lema

Invest Ophthalmol Vis Sci· May 2025

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Elevated Serum Levels of Acid Sphingomyelinase in Female Patients with Episodic and Chronic Migraine.
Alberto Ouro, Mónica Castro-Mosquera, Mariña Rodríguez-Arrizabalaga, Manuel Debasa-Mouce, Antía Custodia, Isabel Lema

Antioxidants (Basel)· January 2025

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Biomedical Applications of Lactoferrin on the Ocular Surface.
Uxía Regueiro, Maite López-López, Rubén Varela-Fernández, Francisco Javier Otero-Espinar, Isabel Lema

Pharmaceutics· March 2023

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Immunomodulatory Effect of Human Lactoferrin on Toll-like Receptors 2 Expression as Therapeutic Approach for Keratoconus.
Uxía Regueiro, Maite López-López, Rubén Varela-Fernández, Tomás Sobrino, Elio Diez-Feijoo, Isabel Lema

Int J Mol Sci· October 2022

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Shotgun Proteomics for the Identification and Profiling of the Tear Proteome of Keratoconus Patients.
Maite López-López, Uxía Regueiro, Susana Belén Bravo, María Del Pilar Chantada-Vázquez, Carmen Pena, Isabel Lema

Invest Ophthalmol Vis Sci· May 2022

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Mucoadhesive PLGA Nanospheres and Nanocapsules for Lactoferrin Controlled Ocular Delivery.
Rubén Varela-Fernández, Xurxo García-Otero, Victoria Díaz-Tomé, Uxía Regueiro, Maite López-López, María Isabel Lema

Pharmaceutics· April 2022

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Lactoferrin-loaded nanostructured lipid carriers (NLCs) as a new formulation for optimized ocular drug delivery.
Rubén Varela-Fernández, Xurxo García-Otero, Victoria Díaz-Tomé, Uxía Regueiro, Maite López-López, María Isabel Lema

Eur J Pharm Biopharm· March 2022

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Alzheimer's Disease Seen through the Eye: Ocular Alterations and Neurodegeneration.
Daniel Romaus-Sanjurjo, Uxía Regueiro, Maite López-López, Laura Vázquez-Vázquez, Alberto Ouro, Isabel Lema

Int J Mol Sci· February 2022

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Tear Proteomics in Keratoconus: A Quantitative SWATH-MS Analysis.
Maite López-López, Uxía Regueiro, Susana B Bravo, María Del Pilar Chantada-Vázquez, Rubén Varela-Fernández, Isabel Lema

Invest Ophthalmol Vis Sci· August 2021

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Corneal and conjunctival alteration of innate immune expression in first-degree relatives of keratoconus patients.
Uxía Regueiro, Maite López-López, Pablo Hervella, Tomás Sobrino, Isabel Lema

Graefes Arch Clin Exp Ophthalmol· February 2021

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Toll-like receptors as diagnostic targets in pellucid marginal degeneration.
Uxía Regueiro, María Pérez-Mato, Pablo Hervella, Francisco Campos, Tomás Sobrino, Isabel Lema

Exp Eye Res· November 2020

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Innate Immunity Biomarkers for Early Detection of Keratoconus.
Mercedes Malfeito, Uxía Regueiro, María Pérez-Mato, Francisco Campos, Tomás Sobrino, Isabel Lema

Ocul Immunol Inflamm· February 2020

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Problems and Barriers during the Process of Clinical Coding: a Focus Group Study of Coders' Perceptions.
Vera Alonso, João Vasco Santos, Marta Pinto, Joana Ferreira, Isabel Lema

J Med Syst· February 2020

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Health records as the basis of clinical coding: Is the quality adequate? A qualitative study of medical coders' perceptions.
Vera Alonso, João Vasco Santos, Marta Pinto, Joana Ferreira, Isabel Lema

Health Inf Manag· January 2020

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Higher Expression of Toll-Like Receptors 2 and 4 in Blood Cells of Keratoconus Patiens.
Tomás Sobrino, Uxía Regueiro, Mercedes Malfeito, Alba Vieites-Prado, María Pérez-Mato, Isabel Lema

Sci Rep· October 2017

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In vivo eye surface residence determination by high-resolution scintigraphy of a novel ion-sensitive hydrogel based on gellan gum and kappa-carrageenan.
Anxo Fernández-Ferreiro, Jesús Silva-Rodríguez, Francisco Javier Otero-Espinar, Miguel González-Barcia, María Jesús Lamas, Isabel Lema

Eur J Pharm Biopharm· May 2017

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In vitro and in vivo ocular safety and eye surface permanence determination by direct and Magnetic Resonance Imaging of ion-sensitive hydrogels based on gellan gum and kappa-carrageenan.
Anxo Fernández-Ferreiro, Miguel González Barcia, María Gil-Martínez, Alba Vieites-Prado, Isabel Lema

Eur J Pharm Biopharm· August 2015

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Vascular retinal, neuroimaging and ultrasonographic markers of lacunar infarcts.
Iria Rodríguez, Isabel Lema, Miguel Blanco, Manuel Rodríguez-Yáñez, Rogelio Leira

Int J Stroke· October 2010

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Proteomic analysis of the tear film in patients with keratoconus.
Isabel Lema, David Brea, Raquel Rodríguez-González, Elío Díez-Feijoo, Tomás Sobrino

Mol Vis· October 2010

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Videokeratoscopic indices in relation to epidemiological exposure to keratoconus.
Jose Luis Mato, Isabel Lema, Elío Díez-Feijoo

Graefes Arch Clin Exp Ophthalmol· July 2010

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Corneal descriptive indices in the fellow eye of unilateral keratoconus.
Isabel Lema, Paloma Romero, Jose L Mato, Elío Díez Feijóo

Eye Contact Lens· March 2009

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Unilateral keratoconus: videokeratography and Orbscan study--optical correction.
Isabel Lema, Ana Isabel Suárez, Elío Díez-Feijoo

Eye Contact Lens· January 2009

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Inflammatory markers in the tears of patients with ocular surface disease.
Arantxa Acera, Germán Rocha, Elena Vecino, Isabel Lema, Juan A Durán

Ophthalmic Res· October 2008

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