Publications by authors named "Isabelle Ader"

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Brown adipose tissue activity impacts systemic lactate clearance in male mice.
Rémi Montané, Yannick Jeanson, Damien Lagarde, Spiro Khoury, Léana Porcher-Bibes, Isabelle Ader

J Physiol· November 2025

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Identification of Functional Cellular Markers Related to Human Health, Frailty and Chronological Age.
Chloé Brodeau, Camille Joly, Anaïs Chekroun, Jean Nakhle, Vincent Blase, Isabelle Ader

Aging Cell· September 2025

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Integrative Multimodal Metabolomics to Early Predict Cognitive Decline Among Amyloid Positive Community-Dwelling Older Adults.
Marie Tremblay-Franco, Cécile Canlet, Audrey Carriere, Jean Nakhle, Anne Galinier, Isabelle Ader

J Gerontol A Biol Sci Med Sci· May 2024

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A locally optimised machine learning approach to early prognostication of long-term neurological outcomes after out-of-hospital cardiac arrest.
Vincent Pey, Emmanuel Doumard, Matthieu Komorowski, Antoine Rouget, Clément Delmas, Isabelle Ader

Digit Health· April 2024

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CD36 Drives Metastasis and Relapse in Acute Myeloid Leukemia.
Thomas Farge, Jean Nakhle, Damien Lagarde, Guillaume Cognet, Nathaniel Polley, Isabelle Ader

Cancer Res· September 2023

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Explainable machine learning framework to predict personalized physiological aging.
David Bernard, Emmanuel Doumard, Isabelle Ader, Philippe Kemoun, Jean-Christophe Pagès

Aging Cell· August 2023

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Periostin Plasma Levels and Changes on Physical and Cognitive Capacities in Community-Dwelling Older Adults.
Juan Luis Sánchez-Sánchez, Isabelle Ader, Yannick Jeanson, Valérie Planat-Benard, Bruno Vellas

J Gerontol A Biol Sci Med Sci· March 2023

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Long non-coding RNA and paraspeckle components are translational regulators in hypoxia.
Anne-Claire Godet, Emilie Roussel, Florian David, Fransky Hantelys, Florent Morfoisse, Isabelle Ader

Elife· December 2022

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Lactate fluxes mediated by the monocarboxylate transporter-1 are key determinants of the metabolic activity of beige adipocytes.
Damien Lagarde, Yannick Jeanson, Corinne Barreau, Cedric Moro, Lindsay Peyriga, Isabelle Ader

J Biol Chem· August 2021

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Lactate Fluxes and Plasticity of Adipose Tissues: A Redox Perspective.
Damien Lagarde, Yannick Jeanson, Jean-Charles Portais, Anne Galinier, Isabelle Ader

Front Physiol· June 2021

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The emerging roles of lactate as a redox substrate and signaling molecule in adipose tissues.
Audrey Carrière, Damien Lagarde, Yannick Jeanson, Jean-Charles Portais, Anne Galinier, Isabelle Ader

J Physiol Biochem· May 2020

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Vasohibin1, a new mouse cardiomyocyte IRES trans-acting factor that regulates translation in early hypoxia.
Fransky Hantelys, Anne-Claire Godet, Florian David, Florence Tatin, Edith Renaud-Gabardos, Isabelle Ader

Elife· December 2019

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Human adipose stromal-vascular fraction self-organizes to form vascularized adipose tissue in 3D cultures.
Sandra Muller, Isabelle Ader, Justine Creff, Hélène Leménager, Pauline Achard

Sci Rep· May 2019

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Mass Spectrometry-based Absolute Quantification of 20S Proteasome Status for Controlled Expansion of Human Adipose-derived Mesenchymal Stromal/Stem Cells.
Thomas Menneteau, Bertrand Fabre, Luc Garrigues, Alexandre Stella, Dusan Zivkovic, Isabelle Ader

Mol Cell Proteomics· April 2019

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FTY720 (Fingolimod) Inhibits HIF1 and HIF2 Signaling, Promotes Vascular Remodeling, and Chemosensitizes in Renal Cell Carcinoma Animal Model.
Cécile Gstalder, Isabelle Ader, Olivier Cuvillier

Mol Cancer Ther· October 2016

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Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer.
Isabelle Ader, Cécile Gstalder, Pierre Bouquerel, Muriel Golzio, Guillaume Andrieu

Oncotarget· May 2015

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Inhibition of the GTPase Rac1 mediates the antimigratory effects of metformin in prostate cancer cells.
Béatrice Dirat, Isabelle Ader, Muriel Golzio, Fabienne Massa, Amel Mettouchi

Mol Cancer Ther· February 2015

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Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells.
Leyre Brizuela, Claire Martin, Pauline Jeannot, Isabelle Ader, Cécile Gstalder

Mol Oncol· October 2014

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Synthesis, structures, and selective toxicity to cancer cells of gold(I) complexes involving N-heterocyclic carbene ligands.
Luca Boselli, Isabelle Ader, Maëlle Carraz, Catherine Hemmert, Olivier Cuvillier

Eur J Med Chem· October 2014

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Preclinical evidence that SSR128129E--a novel small-molecule multi-fibroblast growth factor receptor blocker--radiosensitises human glioblastoma.
Isabelle Ader, Caroline Delmas, Nicolas Skuli, Jacques Bonnet, Paul Schaeffer

Eur J Cancer· September 2014

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Hypoxia, therapeutic resistance, and sphingosine 1-phosphate.
Olivier Cuvillier, Isabelle Ader, Pierre Bouquerel, Leyre Brizuela, Cécile Gstalder

Adv Cancer Res· June 2013

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First evidence of sphingosine 1-phosphate lyase protein expression and activity downregulation in human neoplasm: implication for resistance to therapeutics in prostate cancer.
Leyre Brizuela, Isabelle Ader, Catherine Mazerolles, Magalie Bocquet, Bernard Malavaud

Mol Cancer Ther· September 2012

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Hypoxia-inducible factors and sphingosine 1-phosphate signaling.
Olivier Cuvillier, Isabelle Ader

Anticancer Agents Med Chem· November 2011

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The sphingosine kinase-1 survival pathway is a molecular target for the tumor-suppressive tea and wine polyphenols in prostate cancer.
Leyre Brizuela, Audrey Dayon, Nicolas Doumerc, Isabelle Ader, Muriel Golzio

FASEB J· October 2010

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Activation of sphingosine kinase-1 in cancer: implications for therapeutic targeting.
Olivier Cuvillier, Isabelle Ader, Pierre Bouquerel, Leyre Brizuela, Bernard Malavaud

Curr Mol Pharmacol· June 2010

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