Publications by authors named "Isabelle Allaeys"

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Platelet extracellular vesicles and their mitochondrial content improve the mitochondrial bioenergetics of cellular immune recipients.
Martin Pelletier, Yann Breton, Isabelle Allaeys, Yann Becker, Tom Benson, Eric Boilard

October 2023

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Immobilized IgG-containing immune complexes require platelets to recruit neutrophils during inflammation.
Marie Bellio, Isabelle Allaeys, Etienne Doré, Myriam Vaillancourt, Tania Lévesque

J Clin Invest· December 2025

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Antimitochondrial antibodies in systemic lupus erythematosus are associated with and predict nephritis, arterial vascular events, and mortality.
Yann L C Becker, Éric Boilard, Emmanuelle Rollet-Labelle, Christian Lood, Anne-Sophie Julien, Isabelle Allaeys

Ann Rheum Dis· December 2025

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Secretory phospholipase A-IIA targets bacterial extracellular vesicles to modulate immune signaling.
Etienne Doré, Ève Bérubé, Karine Greffard, Satoshi Morozumi, Valérie Chénard, Isabelle Allaeys

Commun Biol· November 2025

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Deficiency in platelet 12-lipoxygenase exacerbates inflammation and disease severity during SARS-CoV-2 infection.
Ana Claudia Dos S P Andrade, Emile Lacasse, Isabelle Dubuc, Leslie Gudimard, Annie Gravel, Isabelle Allaeys

Proc Natl Acad Sci U S A· March 2025

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Targeting Cytokines: Evaluating the Potential of Mesenchymal Stem Cell Derived Extracellular Vesicles in the Management of COVID-19.
Iago Carvalho Schultz, Ana Claudia Dos Santos Pereira Andrade, Isabelle Dubuc, Audrée Laroche, Isabelle Allaeys

Stem Cell Rev Rep· February 2025

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SARS-CoV-2 infection modifies the transcriptome of the megakaryocytes in the bone marrow.
Isabelle Allaeys, Guillaume Lemaire, Mickaël Leclercq, Emile Lacasse, Maude Fleury

Blood Adv· June 2024

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Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36.
Maria N Barrachina, Gerard Pernes, Isabelle C Becker, Isabelle Allaeys, Thomas I Hirsch

Nat Cardiovasc Res· August 2023

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Thermoneutrality and severe malaria: investigating the effect of warmer environmental temperatures on the inflammatory response and disease progression.
Fiorella Vialard, Isabelle Allaeys, George Dong, Minh Phuong Phan, Urvashi Singh

Front Immunol· June 2023

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Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36.
Maria N Barrachina, Gerard Pernes, Isabelle C Becker, Isabelle Allaeys, Thomas I Hirsch

bioRxiv· February 2023

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SARS-CoV-2 Nsp2 Contributes to Inflammation by Activating NF-κB.
Émile Lacasse, Leslie Gudimard, Isabelle Dubuc, Annie Gravel, Isabelle Allaeys

Viruses· January 2023

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Identification of Mitofusin 1 and Complement Component 1q Subcomponent Binding Protein as Mitochondrial Targets in Systemic Lupus Erythematosus.
Yann L C Becker, Jean-Philippe Gagné, Anne-Sophie Julien, Tania Lévesque, Isabelle Allaeys

Arthritis Rheumatol· July 2022

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Cytokines and Lipid Mediators of Inflammation in Lungs of SARS-CoV-2 Infected Mice.
Isabelle Dubuc, Julien Prunier, Émile Lacasse, Annie Gravel, Florian Puhm, Isabelle Allaeys

Front Immunol· July 2022

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Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cells.
Florian Puhm, Isabelle Allaeys, Emile Lacasse, Isabelle Dubuc, Yannick Galipeau

Blood Adv· June 2022

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Live imaging of platelets and neutrophils during antibody-mediated neurovascular thrombosis.
Audree Laroche, Denis Soulet, Marc Bazin, Tania Levesque, Isabelle Allaeys

Blood Adv· June 2022

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The interaction of secreted phospholipase A2-IIA with the microbiota alters its lipidome and promotes inflammation.
Etienne Doré, Charles Joly-Beauparlant, Satoshi Morozumi, Alban Mathieu, Tania Lévesque, Isabelle Allaeys

JCI Insight· January 2022

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Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules.
Genevieve Marcoux, Audrée Laroche, Stephan Hasse, Marie Bellio, Maroua Mbarik, Isabelle Allaeys

Blood· December 2021

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Human Inflammatory Neutrophils Express Genes Encoding Peptidase Inhibitors: Production of Elafin Mediated by NF-κB and CCAAT/Enhancer-Binding Protein β.
Isabelle Allaeys, Flavia Ribeiro de Vargas, Sylvain G Bourgoin, Patrice E Poubelle

J Immunol· April 2021

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Platelets release mitochondrial antigens in systemic lupus erythematosus.
Imene Melki, Isabelle Allaeys, Nicolas Tessandier, Tania Lévesque, Nathalie Cloutier

Sci Transl Med· February 2021

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FcγRIIA expression accelerates nephritis and increases platelet activation in systemic lupus erythematosus.
Imene Melki, Isabelle Allaeys, Nicolas Tessandier, Benoit Mailhot, Nathalie Cloutier

Blood· December 2020

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Platelets Can Associate with SARS-Cov-2 RNA and Are Hyperactivated in COVID-19.
Younes Zaid, Florian Puhm, Isabelle Allaeys, Abdallah Naya, Mounia Oudghiri

Circ Res· September 2020

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Platelet-derived extracellular vesicles infiltrate and modify the bone marrow during inflammation.
Shauna L French, Kirill R Butov, Isabelle Allaeys, Jorge Canas, Golnaz Morad

Blood Adv· July 2020

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Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNA.
Yann Becker, Geneviève Marcoux, Isabelle Allaeys, Anne-Sophie Julien, Renée-Claude Loignon

Front Immunol· June 2020

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Platelets Disseminate Extracellular Vesicles in Lymph in Rheumatoid Arthritis.
Nicolas Tessandier, Imene Melki, Nathalie Cloutier, Isabelle Allaeys, Adam Miszta

Arterioscler Thromb Vasc Biol· April 2020

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Platelet-derived extracellular vesicles convey mitochondrial DAMPs in platelet concentrates and their levels are associated with adverse reactions.
Genevieve Marcoux, Audrey Magron, Caroline Sut, Audree Laroche, Sandrine Laradi, Isabelle Allaeys

Transfusion· July 2019

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