October 2023 PMID 37642274

Platelet extracellular vesicles and their mitochondrial content improve the mitochondrial bioenergetics of cellular immune recipients.

Martin Pelletier, Yann Breton, Isabelle Allaeys, Yann Becker, Tom Benson, Eric Boilard

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Mentions

43
Peak: 19 in Sep 2023
across 3 sources since Aug 2023

Extended reach

290,438
potential audience

Total likes

1,288

Video views

51,504

Mentions per month

Aug 2023 – Sep 2025

Where it's discussed

  • X / Twitter39 posts
  • Bluesky2 posts
  • YouTube2 videos

AI synopsis

What people are saying

Several posts praise the research for its potential to revolutionize immune therapies, with phrases like 'game changer' and 'robust concept,' and mention detailed experimental references, demonstrating both enthusiasm and a deep understanding of the topic.

AgreementStrong agreement

Most discussions emphasize the positive effects of platelet vesicles and mitochondrial transfer, indicating strong support for the study's findings.

InterestHigh interest

Posts highlight various applications, methods, and implications, reflecting high curiosity and engagement with the topic.

EngagementHigh engagement

Many comments reference multiple related papers, share experimental results, and discuss potential therapies, showing deep involvement.

ImpactHigh impact

The widespread praise for mitochondrial transplantation and its potential to reverse aging or treat diseases underscores perceived high impact.

Abstract in brief

  • Platelet-derived extracellular vesicles contain functional mitochondria that can produce energy, and these vesicles can be taken up by immune cells like neutrophils and monocytes, enhancing their mitochondrial function.
  • The presence of mitochondria in these vesicles relies on active mitochondria in the donor platelets, as inactivating them prevents the energy boost in recipient cells.
  • Overall, this study suggests that platelets release mitochondria within vesicles that may help boost the energy and metabolic functions of immune cells, potentially influencing immune responses.]

Top posts

Most liked on X and Bluesky
Mitrix Bio
@PathfinderEq · X

Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength of an immune system weakened by age or mitochondrial mutation. https://t.co/8tFHo99lFj https://t.co/OzxkOqb3X2 @MitoPsychoBio @Madam_Mito @ChrisPalmerMD

Sep 20, 2023 · 48 likes · 15 shares · 4,884 followers View post →
Mitrix Bio
@PathfinderEq · X

@ImmunoFever @dysclinic @MitoPsychoBio @BrestoffLab @vijayiyer312 @rjhomer57 @susan_mecfs Let us humbly suggest our papers from last year (in-vivo tests and in-vitro tests, read them together...) https://t.co/8tFHo99lFj https://t.co/5KcrTpwjdv In essence, we showed that blood mitochondrial from young mice, transplanted in massive amounts into elderly mice with sepsis

May 11, 2024 · 15 likes · 2 shares · 4,884 followers View post →
Taiki Baba
@babataiki326 · X

Platelet extracellular vesicles and their mitochondrial content improve the mitochondrial bioenergetics of cellular immune recipients. (2023) Transfusion https://t.co/6YdXHizkkH

Aug 29, 2023 · 8 likes · 2,719 followers View post →
Mitrix Bio
@PathfinderEq · X

@agingdoc1 Congratulations to @CoCo_Headley and team We recently found the same effect in other types of immune cells + rescue of aged mice from Sepsis and H1N1. This is a very robust concept! "Platelet extracellular vesicles and their mitochondrial content improve the mitochondrial

Nov 25, 2023 · 5 likes · 4,884 followers View post →
Exosome RNA
@ExosomeRNA · X

Researchers at the @crchuqc characterized #mitochondrial functions in platelet-derived #extracellularvesicles, and examined whether they could impact the #bioenergetics of cellular immune recipients using an extracellular flux analyzer to measure... https://t.co/hpKuBVWLrh

Sep 1, 2023 · 4 likes · 3,386 followers View post →
Mitrix Bio
@PathfinderEq · X

@stanete @Madam_Mito @paulg Here's our 3 publications on the topic (2 just published last week) Transfusion:  https://t.co/OzxkOqb3X2 BioRxiv (should be read with Transfusion paper):  https://t.co/ziOG1VSOOd Alzheimer's results from last year: https://t.co/jLjHJdt1IG Google "mitochondrial

Sep 28, 2023 · 3 likes · 4,884 followers View post →

All mentions

Rene Sugar
@renesugar · X

@AndrewG76201347 eg. Platelet extracellular vesicles and their mitochondrial content improve the mitochondrial bioenergetics of cellular immune recipients https://t.co/MBmyu1JL1L https://t.co/zZMtiWhyi1

Sep 19, 2025 · 3,974 followers View post →
Rene Sugar
@renesugar · X

@Sabrina_Poirier @sunsopeningband The mitochondria can be from someone else (eg. platelet donation) to change immune response. Platelet extracellular vesicles and their mitochondrial content improve the mitochondrial bioenergetics of cellular immune recipients https://t.co/MBmyu1KiRj https://t.co/zZMtiWi67z

Mar 30, 2025 · 3,974 followers View post →
luis hernan graffe
@hernangraffe · X

RT @hernangraffe: https://t.co/5QQoTmYqLS

Sep 17, 2024 · 1 share · 3,150 followers View post →
luis hernan graffe
@hernangraffe · X

https://t.co/5QQoTmYqLS

Sep 13, 2024 · 1 share · 3,150 followers View post →
Rene Sugar
@renesugar · X

RT @PathfinderEq: @ImmunoFever @dysclinic @MitoPsychoBio @BrestoffLab @vijayiyer312 @rjhomer57 @susan_mecfs Let us humbly suggest our paper…

May 11, 2024 · 2 shares · 3,974 followers View post →
Michal Tal, PhD
@ImmunoFever · X

RT @PathfinderEq: @ImmunoFever @dysclinic @MitoPsychoBio @BrestoffLab @vijayiyer312 @rjhomer57 @susan_mecfs Let us humbly suggest our paper…

May 11, 2024 · 2 shares · 14,301 followers View post →
Mitrix Bio
@PathfinderEq · X

@ImmunoFever @dysclinic @MitoPsychoBio @BrestoffLab @vijayiyer312 @rjhomer57 @susan_mecfs Let us humbly suggest our papers from last year (in-vivo tests and in-vitro tests, read them together...) https://t.co/8tFHo99lFj https://t.co/5KcrTpwjdv In essence, we showed that blood mitochondrial from young mice, transplanted in massive amounts into elderly mice with sepsis

May 11, 2024 · 15 likes · 2 shares · 4,884 followers View post →
Danny Flinker
@FlinkerDanny · X

https://t.co/3AgCL6AZ18

Feb 8, 2024 · 149 followers View post →
George Tsimpedes
@GTsimpedes71310 · X

AGE REVERSAL Through Replacing MITOCHONDRIA https://t.co/WjmJU2cHcP via @YouTube

Jan 20, 2024 · 104 followers View post →
Eugene
@eugediana · X

https://t.co/6SQBsbQMWq In mice but…

Jan 15, 2024 · 220 followers View post →
Fitness Fervor
@FitnessFervor · X

Jan 11, 2024 · 2,130 followers View post →
luis hernan graffe
@hernangraffe · X

https://t.co/ju73o3kNvh

Jan 10, 2024 · 3,150 followers View post →
Paola De Gennaro
@PaolaDeGennar10 · X

https://t.co/LpDBVQcw4m

Jan 10, 2024 · 1 like · 211 followers View post →
Gary D
@horizon1685 · X

RT @wdmorgan2: AGE REVERSAL Through Replacing MITOCHONDRIA https://t.co/HnzC7PC2qW

Jan 9, 2024 · 1 share · 203 followers View post →
Copy&Paste©️
@wdmorgan2 · X

AGE REVERSAL Through Replacing MITOCHONDRIA https://t.co/HnzC7PC2qW

Jan 9, 2024 · 1 like · 1 share · 3,236 followers View post →
Hak Wan
@wan88super · X

AGE REVERSAL Through Replacing MITOCHONDRIA https://t.co/0JdPg4ERlj via @YouTube

Jan 9, 2024 · 1,094 followers View post →
BEAST magazine
@beast_media_net · X

AGE REVERSAL Through Replacing MITOCHONDRIA https://t.co/ZxiI9l1P66 via @YouTube

Jan 9, 2024 · 1,202 followers View post →
homer60
@homer604 · X

AGE REVERSAL Through Replacing MITOCHONDRIA https://t.co/YCOaOgH8dD via @YouTube

Jan 8, 2024 · 114 followers View post →
Mitrix Bio
@PathfinderEq · X

@agingdoc1 Congratulations to @CoCo_Headley and team We recently found the same effect in other types of immune cells + rescue of aged mice from Sepsis and H1N1. This is a very robust concept! "Platelet extracellular vesicles and their mitochondrial content improve the mitochondrial

Nov 25, 2023 · 5 likes · 4,884 followers View post →
Mind Your Science!
@MindYourSci · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Oct 2, 2023 · 15 shares · 132 followers View post →
Mitrix Bio
@PathfinderEq · X

@stanete @Madam_Mito @paulg Here's our 3 publications on the topic (2 just published last week) Transfusion:  https://t.co/OzxkOqb3X2 BioRxiv (should be read with Transfusion paper):  https://t.co/ziOG1VSOOd Alzheimer's results from last year: https://t.co/jLjHJdt1IG Google "mitochondrial

Sep 28, 2023 · 3 likes · 4,884 followers View post →
ARThrite-UL - Arthrite, Recherche et Traitements
@CentreARThrite · X

Un nouvel article du Dr. Martin Pelletier et du Dr. Eric Boilard éclaire certains des mécanismes fascinants des mitlets, des vésicules extracellulaires sécrétées par les plaquettes et transportant des mitochondries !

Sep 21, 2023 · 2 likes · 36 followers View post →
Michele
@michele_mattea · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Sep 20, 2023 · 15 shares · 971 followers View post →
Aneta Molenda
@a_m_molenda · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Sep 20, 2023 · 15 shares · 592 followers View post →
Flor
@lugaresxcomunes · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Sep 20, 2023 · 15 shares · 1,573 followers View post →
PostX #UniteToFight2024
@TeamPostX · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Sep 20, 2023 · 15 shares · 2,070 followers View post →
Tarik Fehmi
@Tarik_Fehmi · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Sep 20, 2023 · 15 shares · 816 followers View post →
Rene Sugar
@renesugar · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Sep 20, 2023 · 15 shares · 3,974 followers View post →
Xanthi
@Xanthi00164319 · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Sep 20, 2023 · 15 shares · 125 followers View post →
HotelLasVegas.com(TM)
@hotellasvegas_ · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Sep 20, 2023 · 15 shares · 2,732 followers View post →
WJW Mental Health Legal Fund
@wjwmhlf · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Sep 20, 2023 · 15 shares · 1,296 followers View post →
Christoph Bammer
@CBammerMD · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Sep 20, 2023 · 15 shares · 1,351 followers View post →
Ernest Lancaster
@ErnestLancaste7 · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Sep 20, 2023 · 15 shares · 1,246 followers View post →
Chris Palmer, MD
@ChrisPalmerMD · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Sep 20, 2023 · 15 shares · 136,059 followers View post →
Madam Mitochondria
@Madam_Mito · X

RT @PathfinderEq: Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength o…

Sep 20, 2023 · 15 shares · 10,630 followers View post →
Mitrix Bio
@PathfinderEq · X

Proud to announce 2 new papers from Mitrix, describing the use of mitochondrial transplantation to restore the strength of an immune system weakened by age or mitochondrial mutation. https://t.co/8tFHo99lFj https://t.co/OzxkOqb3X2 @MitoPsychoBio @Madam_Mito @ChrisPalmerMD

Sep 20, 2023 · 48 likes · 15 shares · 4,884 followers View post →
bioRxiv Molecular Biology
@biorxiv-molbio.bsky.social · Bluesky

Platelet extracellular vesicles and their mitochondrial content significantly improve survival and cytokine levels when transfused into mice with sepsis or H1N1 infections https://www.biorxiv.org/content/10.1101/2023.09.08.556161v1

Sep 12, 2023 View post →
bioRxivpreprint
@biorxivpreprint.bsky.social · Bluesky

Platelet extracellular vesicles and their mitochondrial content significantly improve survival and cytokine levels when transfused into mice with sepsis or H1N1 infections https://www.biorxiv.org/content/10.1101/2023.09.08.556161v1

Sep 12, 2023 · 1 like View post →
Exosome RNA
@ExosomeRNA · X

Researchers at the @crchuqc characterized #mitochondrial functions in platelet-derived #extracellularvesicles, and examined whether they could impact the #bioenergetics of cellular immune recipients using an extracellular flux analyzer to measure... https://t.co/hpKuBVWLrh

Sep 1, 2023 · 4 likes · 3,386 followers View post →
Mitrix Bio
@PathfinderEq · X

@Ketogenic_EU @catsocialintel @cure_mito @PutrinoLab The roadblock is the same for anybody in the entire biotech industry. Almost total collapse of funding for 18 months. Good companies developing lifesaving treatments unable to continue at all By the way, just published a new paper: https://t.co/OzxkOqb3X2 A bit on the

Aug 30, 2023 · 1 like · 4,884 followers View post →
Taiki Baba
@babataiki326 · X

Platelet extracellular vesicles and their mitochondrial content improve the mitochondrial bioenergetics of cellular immune recipients. (2023) Transfusion https://t.co/6YdXHizkkH

Aug 29, 2023 · 8 likes · 2,719 followers View post →