Publications by authors named "Isabelle Deschenes"

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Regulation of atrial and ventricular cardiomyocyte identity.
Shuliang Guo, Yingwei Liu, Angela Ryan, Ana Laura Lopez Serrano, Isabelle Deschenes

J Mol Cell Cardiol· November 2025

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The two-pore K channel TREK-1 regulates pressure overload-induced cardiac remodeling.
Cemantha M L Johnson, Drew M Nassal, Alexander J Winkle, Benjamin Buck, Xianyao Xu

Am J Physiol Heart Circ Physiol· July 2025

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Pharmacological Enhancement of Small Conductance Ca-Activated K Channels Suppresses Cardiac Arrhythmias in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia.
Roland Veress, Radmila Terentyeva, Andriy E Belevych, Fruzsina Perger, Zuzana Nichtova, Isabelle Deschenes

Circ Res· July 2025

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Structural and Functional Mechanisms Underlying Activation Gate Dynamics and IFM Motif Accessibility in Human Na1.5.
Rupam Biswas, Ana Laura López-Serrano, Apoorva Purohit, Angelina Ramirez-Navarro, Hsiang-Ling Huang

bioRxiv· July 2025

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Advanced 4-chamber echocardiography techniques enable clinically matched precise characterization of heart disease progression in mice.
Ege Kacira, Mariam F Oueis, Nawal H Tamimi, Sarah L Sturgill, Xianyao Xu

Commun Med (Lond)· July 2025

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The Role of Global Longitudinal Strain in Detecting Early Left Ventricular Dysfunction in Pediatric Bicuspid Aortic Valve Patients.
Mohammed A Mashali, Isabelle Deschênes, Carl V Leier, Nancy S Saad

Children (Basel)· June 2025

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Age-Associated Perinexal Narrowing Masks Consequences of Sodium Channel Gain of Function in Guinea Pig Hearts.
Xiaobo Wu, David Ryan King, Gregory S Hoeker, Xiaoping Wan, Isabelle Deschenes

JACC Clin Electrophysiol· May 2025

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Structural basis of human Na1.5 gating mechanisms.
Rupam Biswas, Ana Laura López-Serrano, Apoorva Purohit, Angelina Ramirez-Navarro, Hsiang-Ling Huang

Proc Natl Acad Sci U S A· May 2025

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Transformative Potential of Induced Pluripotent Stem Cells in Congenital Heart Disease Research and Treatment.
Mohammed A Mashali, Isabelle Deschênes, Nancy S Saad

Children (Basel)· May 2025

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Isolated Cardiac Ryanodine Receptor Function Varies Between Mammals.
Catherine Carvajal, Jiajie Yan, Alma Nani, Jaime DeSantiago, Xiaoping Wan, Isabelle Deschenes

J Membr Biol· April 2024

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Structural basis of human Na1.5 gating mechanisms.
Rupam Biswas, Ana López-Serrano, Hsiang-Ling Huang, Angelina Ramirez-Navarro, Giovanna Grandinetti

Res Sq· April 2024

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Persistent PKA activation redistributes NaV1.5 to the cell surface of adult rat ventricular myocytes.
Tytus Bernas, John Seo, Zachary T Wilson, Bi-Hua Tan, Isabelle Deschenes

J Gen Physiol· February 2024

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Long-Axis Biplane Echocardiography Sensitively Detects the Progressing Functional Deterioration of Mouse Heart.
Ege Kacira, Mitchell Pittman, Dandan Yang, Sarah L Sturgill, Mark T Ziolo

Circ Heart Fail· January 2024

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MicroRNA-1 Deficiency Is a Primary Etiological Factor Disrupting Cardiac Contractility and Electrophysiological Homeostasis.
Dandan Yang, Xiaoping Wan, Neill Schwieterman, Omer Cavus, Ege Kacira

Circ Arrhythm Electrophysiol· January 2024

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Advances in understanding of cardiac sodium channel structure/function and their relation to disease pathogenesis and treatment.
Isabelle Deschênes, Rupam Biswas, Krishna Chinthalapudi

Heart Rhythm· January 2024

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Biophysical characterization of chloride intracellular channel 6 (CLIC6).
Veronica Loyo-Celis, Devendra Patel, Shridhar Sanghvi, Kamalpreet Kaur, Devasena Ponnalagu, Isabelle Deschenes

J Biol Chem· November 2023

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Extracellular Perinexal Separation Is a Principal Determinant of Cardiac Conduction.
William P Adams, Tristan B Raisch, Yajun Zhao, Rafael Davalos, Sarah Barrett, Isabelle Deschenes

Circ Res· September 2023

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Protein 14-3-3 Influences the Response of the Cardiac Sodium Channel Na1.5 to Antiarrhythmic Drugs.
Yang Zheng, Isabelle Deschênes

J Pharmacol Exp Ther· March 2023

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Impaired Human Cardiac Cell Development due to NOTCH1 Deficiency.
Shiqiao Ye, Cankun Wang, Zhaohui Xu, Hui Lin, Xiaoping Wan, Isabelle Deschenes

Circ Res· January 2023

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Precision medicine for long QT syndrome: patient-specific iPSCs take the lead.
Yang Yu, Isabelle Deschenes, Ming-Tao Zhao

Expert Rev Mol Med· January 2023

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Trafficking and Gating Cooperation Between Deficient Na1.5-mutant Channels to Rescue I.
Jérôme Clatot, Alain Coulombe, Isabelle Deschênes, Pascale Guicheney, Nathalie Neyroud

Front Biosci (Landmark Ed)· June 2022

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Multilayer control of cardiac electrophysiology by microRNAs.
Dandan Yang, Isabelle Deschênes, Ji-Dong Fu

J Mol Cell Cardiol· May 2022

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Inhibition of CREB-CBP Signaling Improves Fibroblast Plasticity for Direct Cardiac Reprogramming.
Emre Bektik, Yu Sun, Adrienne T Dennis, Phraew Sakon, Dandan Yang

Cells· June 2021

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A Heart Failure-Associated Splice Variant Leads to a Reduction in Sodium Current Through Coupled-Gating With the Wild-Type Channel.
Yang Zheng, Xiaoping Wan, Dandan Yang, Angelina Ramirez-Navarro, Haiyan Liu

Front Physiol· March 2021

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Long QT syndrome - Bench to bedside.
Daniela Ponce-Balbuena, Isabelle Deschênes

Heart Rhythm O2· February 2021

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