Publications by authors named "Isabelle Gallais"

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Key role of extracellular vesicles in the induction of necroptosis and apoptosis by a mixture of polycyclic aromatic hydrocarbons in the context of a steatohepatitis-like state.
Florian Barathon, Paul-Henri Graindorge, Maelle Bescher, Isabelle Gallais, Agnès Burel

Toxicology· September 2025

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Early stage of metabolic dysfunction associated steatotic liver disease disrupts circadian rhythm and induces neuroinflammation in rats.
Paul-Henri Graindorge, Justine Paoli, Berivan Yildirim, Chloe Morel, Ameziane Herzine, Isabelle Gallais

Sci Rep· March 2025

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Deciphering the Role of PIG1 and DHN-Melanin in Conidia.
Hélène Guegan, Wilfried Poirier, Kevin Ravenel, Sarah Dion, Aymeric Delabarre, Isabelle Gallais

J Fungi (Basel)· January 2023

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HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent gene repression in murine erythroleukaemia.
Sebastian Gregoricchio, Lélia Polit, Michela Esposito, Jérémy Berthelet, Laure Delestré, Isabelle Gallais

Nucleic Acids Res· August 2022

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TRIM21, a New Component of the TRAIL-Induced Endogenous Necrosome Complex.
Mélanie Simoes Eugénio, Florence Faurez, Ghania H Kara-Ali, Mélanie Lagarrigue, Perrine Uhart, Isabelle Gallais

Front Mol Biosci· April 2021

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MEHP/ethanol co-exposure favors the death of steatotic hepatocytes, possibly through CYP4A and ADH involvement.
Arnaud Tête, Isabelle Gallais, Muhammad Imran, Louis Legoff, Corinne Martin-Chouly

Food Chem Toxicol· December 2020

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Extracellular vesicles released by polycyclic aromatic hydrocarbons-treated hepatocytes trigger oxidative stress in recipient hepatocytes by delivering iron.
Nettie van Meteren, Dominique Lagadic-Gossmann, Normand Podechard, Dimitri Gobart, Isabelle Gallais

Free Radic Biol Med· November 2020

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Polycyclic Aromatic Hydrocarbons Can Trigger Hepatocyte Release of Extracellular Vesicles by Various Mechanisms of Action Depending on Their Affinity for the Aryl Hydrocarbon Receptor.
Nettie van Meteren, Dominique Lagadic-Gossmann, Martine Chevanne, Isabelle Gallais, Dimitri Gobart

Toxicol Sci· October 2019

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Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene.
Bendik C Brinchmann, Eric Le Ferrec, William H Bisson, Normand Podechard, Henrik S Huitfeldt, Isabelle Gallais

Biochem Pharmacol· December 2018

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Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide.
Arnaud Tête, Isabelle Gallais, Muhammad Imran, Martine Chevanne, Marie Liamin

Free Radic Biol Med· December 2018

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Membrane Remodeling as a Key Player of the Hepatotoxicity Induced by Co-Exposure to Benzo[a]pyrene and Ethanol of Obese Zebrafish Larvae.
Muhammad Imran, Odile Sergent, Arnaud Tête, Isabelle Gallais, Martine Chevanne

Biomolecules· May 2018

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Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo.
Simon Bucher, Arnaud Tête, Normand Podechard, Marie Liamin, Dounia Le Guillou, Isabelle Gallais

Sci Rep· April 2018

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Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis.
Fabienne Le Cann, Claire Delehouzé, Sabrina Leverrier-Penna, Aveline Filliol, Arnaud Comte, Isabelle Gallais

FEBS J· September 2017

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Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype.
Kévin Hardonnière, Morgane Fernier, Isabelle Gallais, Baharia Mograbi, Normand Podechard

Sci Rep· March 2017

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The environmental carcinogen benzo[a]pyrene induces a Warburg-like metabolic reprogramming dependent on NHE1 and associated with cell survival.
Kévin Hardonnière, Elise Saunier, Anthony Lemarié, Morgane Fernier, Isabelle Gallais

Sci Rep· August 2016

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Benzo[a]pyrene-induced nitric oxide production acts as a survival signal targeting mitochondrial membrane potential.
Kévin Hardonnière, Laurence Huc, Normand Podechard, Morgane Fernier, Xavier Tekpli, Isabelle Gallais

Toxicol In Vitro· October 2015

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Oncogenic kit triggers Shp2/Erk1/2 pathway to down-regulate the pro-apoptotic protein Bim and to promote apoptosis resistance in leukemic cells.
Dorothée Selimoglu-Buet, Isabelle Gallais, Nicole Denis, Christel Guillouf, Françoise Moreau-Gachelin

PLoS One· July 2013

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Spi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemia.
Maya Ridinger-Saison, Valentina Boeva, Pauline Rimmelé, Ivan Kulakovskiy, Isabelle Gallais

Nucleic Acids Res· October 2012

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Cotargeting signaling pathways driving survival and cell cycle circumvents resistance to Kit inhibitors in leukemia.
Dorothée Buet, Isabelle Gallais, Evelyne Lauret, Nicole Denis, Bérangère Lombard

Blood· May 2012

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Erythropoietin down-regulates stem cell factor receptor (Kit) expression in the leukemic proerythroblast: role of Lyn kinase.
Olivier Kosmider, Dorothée Buet, Isabelle Gallais, Nicole Denis, Françoise Moreau-Gachelin

PLoS One· May 2009

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Ezrin is a target for oncogenic Kit mutants in murine erythroleukemia.
Richard Monni, Lamya Haddaoui, Alexandra Naba, Isabelle Gallais, Monique Arpin

Blood· March 2008

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Spi-1/PU.1 oncoprotein affects splicing decisions in a promoter binding-dependent manner.
Christel Guillouf, Isabelle Gallais, Françoise Moreau-Gachelin

J Biol Chem· July 2006

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Multiple functional domains of the oncoproteins Spi-1/PU.1 and TLS are involved in their opposite splicing effects in erythroleukemic cells.
Laurent Delva, Isabelle Gallais, Christel Guillouf, Nicole Denis, Christophe Orvain

Oncogene· May 2004

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