Publications by authors named "Isabelle Gerin"

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A missing enzyme-rescue metabolite as cause of a rare skeletal dysplasia.
Jean Jacobs, Hristiana Lyubenova, Sven Potelle, Johannes Kopp, Isabelle Gerin

Nature· October 2025

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PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma.
Valentin Van den Bossche, Julie Vignau, Engy Vigneron, Isabella Rizzi, Hannah Zaryouh, Isabelle Gerin

Nat Commun· February 2025

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ACAD10 and ACAD11 allow entry of 4-hydroxy fatty acids into β-oxidation.
Stéphanie Paquay, Julia Duraffourd, Marina Bury, Isaac P Heremans, Francesco Caligiore, Isabelle Gerin

Cell Mol Life Sci· August 2024

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SUZ domain-containing proteins have multiple effects on nonsense-mediated decay target transcripts.
Mathias Halbout, Marina Bury, Aoife Hanet, Isabelle Gerin, Julie Graff

J Biol Chem· September 2023

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Parkinson's disease protein PARK7 prevents metabolite and protein damage caused by a glycolytic metabolite.
Isaac P Heremans, Francesco Caligiore, Isabelle Gerin, Marina Bury, Marilena Lutz

Proc Natl Acad Sci U S A· January 2022

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Brief O uploading during continuous hypothermic machine perfusion is simple yet effective oxygenation method to improve initial kidney function in a porcine autotransplant model.
Tom Darius, Martial Vergauwen, Thomas Smith, Isabelle Gerin, Virginie Joris

Am J Transplant· August 2020

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The synthesis of branched-chain fatty acids is limited by enzymatic decarboxylation of ethyl- and methylmalonyl-CoA.
Joseph P Dewulf, Isabelle Gerin, Mark H Rider, Maria Veiga-da-Cunha, Emile Van Schaftingen

Biochem J· August 2019

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Phosphoglycolate has profound metabolic effects but most likely no role in a metabolic DNA response in cancer cell lines.
Isabelle Gerin, Marina Bury, Francesca Baldin, Julie Graff, Emile Van Schaftingen

Biochem J· February 2019

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A conserved phosphatase destroys toxic glycolytic side products in mammals and yeast.
François Collard, Francesca Baldin, Isabelle Gerin, Jennifer Bolsée, Gaëtane Noël

Nat Chem Biol· August 2016

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ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycan.
Isabelle Gerin, Benoît Ury, Isabelle Breloy, Céline Bouchet-Seraphin, Jennifer Bolsée

Nat Commun· May 2016

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SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling.
Shannon Liu, Ruichuan Xu, Isabelle Gerin, William P Cawthorn, Ormond A Macdougald

PLoS One· June 2015

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Identification of TP53-induced glycolysis and apoptosis regulator (TIGAR) as the phosphoglycolate-independent 2,3-bisphosphoglycerate phosphatase.
Isabelle Gerin, Gaëtane Noël, Jennifer Bolsée, Olivier Haumont, Emile Van Schaftingen

Biochem J· March 2014

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Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition.
Hiroyuki Mori, Tyler C Prestwich, Michael A Reid, Kenneth A Longo, Isabelle Gerin

J Clin Invest· July 2012

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Multiple roles for the non-coding RNA SRA in regulation of adipogenesis and insulin sensitivity.
Bin Xu, Isabelle Gerin, Hongzhi Miao, Dang Vu-Phan, Craig N Johnson

PLoS One· December 2010

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Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation.
Isabelle Gerin, Laure-Alix Clerbaux, Olivier Haumont, Nicolas Lanthier, Arun K Das

J Biol Chem· October 2010

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Roles for miRNA-378/378* in adipocyte gene expression and lipogenesis.
Isabelle Gerin, Guido T Bommer, Colin S McCoin, Kyle M Sousa, Venkatesh Krishnan

Am J Physiol Endocrinol Metab· August 2010

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Hyperphagia and obesity in female mice lacking tissue inhibitor of metalloproteinase-1.
Isabelle Gerin, Gwendolyn W Louis, Xuan Zhang, Tyler C Prestwich, T Rajendra Kumar

Endocrinology· April 2009

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Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis.
Bin Xu, Wei-Hsiung Yang, Isabelle Gerin, Chang-Deng Hu, Gary D Hammer

Mol Cell Biol· April 2009

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On the role of FOX transcription factors in adipocyte differentiation and insulin-stimulated glucose uptake.
Isabelle Gerin, Guido T Bommer, Martin E Lidell, Anna Cederberg, Sven Enerback

J Biol Chem· April 2009

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The microRNA miR-8 is a conserved negative regulator of Wnt signaling.
Jennifer A Kennell, Isabelle Gerin, Ormond A MacDougald, Ken M Cadigan

Proc Natl Acad Sci U S A· October 2008

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Fat-specific protein 27 regulates storage of triacylglycerol.
Pernille Keller, John T Petrie, Paul De Rose, Isabelle Gerin, Wendy S Wright

J Biol Chem· May 2008

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Resistance to diet-induced obesity and improved insulin sensitivity in mice with a regulator of G protein signaling-insensitive G184S Gnai2 allele.
Xinyan Huang, Raelene A Charbeneau, Ying Fu, Kuljeet Kaur, Isabelle Gerin

Diabetes· January 2008

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Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation.
Christina N Bennett, Hongjiao Ouyang, Yanfei L Ma, Qingqiang Zeng, Isabelle Gerin

J Bone Miner Res· December 2007

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p53-mediated activation of miRNA34 candidate tumor-suppressor genes.
Guido T Bommer, Isabelle Gerin, Ying Feng, Andrew J Kaczorowski, Rork Kuick

Curr Biol· August 2007

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Wnt signaling stimulates osteoblastogenesis of mesenchymal precursors by suppressing CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma.
Sona Kang, Christina N Bennett, Isabelle Gerin, Lauren A Rapp, Kurt D Hankenson

J Biol Chem· May 2007

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