Publications by authors named "Isabelle Girault"

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ChemR23 activation reprograms macrophages toward a less inflammatory phenotype and dampens carcinoma progression.
Margot Lavy, Vanessa Gauttier, Alison Dumont, Florian Chocteau, Sophie Deshayes, Isabelle Girault

Front Immunol· August 2023

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First-in-Human Study in Healthy Subjects with the Noncytotoxic Monoclonal Antibody OSE-127, a Strict Antagonist of IL-7Rα.
Nicolas Poirier, Irène Baccelli, Lyssia Belarif, Riad Abès, Géraldine Teppaz, Isabelle Girault

J Immunol· March 2023

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CLEC-1 is a death sensor that limits antigen cross-presentation by dendritic cells and represents a target for cancer immunotherapy.
Marion Drouin, Javier Saenz, Vanessa Gauttier, Berangere Evrard, Geraldine Teppaz, Isabelle Girault

Sci Adv· November 2022

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Neuropilin-1 cooperates with PD-1 in CD8 T cells predicting outcomes in melanoma patients treated with anti-PD1.
Julien Rossignol, Zakia Belaid, Guillemette Fouquet, Flavia Guillem, Rachel Rignault, Isabelle Girault

iScience· June 2022

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Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy.
Assia Asrir, Claire Tardiveau, Juliette Coudert, Robin Laffont, Lucas Blanchard, Isabelle Girault

Cancer Cell· March 2022

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A PD-1/PD-L1 Proximity Assay as a Theranostic Marker for PD-1 Blockade in Patients with Metastatic Melanoma.
Isabelle Girault, Julien Adam, Shensi Shen, Séverine Roy, Caroline Brard

Clin Cancer Res· February 2022

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detection of the eIF4F translation initiation complex in mammalian cells and tissues.
Shensi Shen, Isabelle Girault, Hélène Malka-Mahieu, Caroline Robert, Stéphan Vagner

STAR Protoc· September 2021

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Selective SIRPα blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance.
Vanessa Gauttier, Sabrina Pengam, Justine Durand, Kevin Biteau, Caroline Mary, Isabelle Girault

J Clin Invest· November 2020

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Evaluation of the efficacy of immunotherapy for non-resectable mucosal melanoma.
Antoine Moya-Plana, Ruth Gabriela Herrera Gómez, Caroline Rossoni, Laurent Dercle, Samy Ammari, Isabelle Girault

Cancer Immunol Immunother· July 2019

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Translational control of tumor immune escape via the eIF4F-STAT1-PD-L1 axis in melanoma.
Michaël Cerezo, Ramdane Guemiri, Sabine Druillennec, Isabelle Girault, Hélène Malka-Mahieu

Nat Med· December 2018

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Synergistic effects of eIF4A and MEK inhibitors on proliferation of NRAS-mutant melanoma cell lines.
Hélène Malka-Mahieu, Isabelle Girault, Margot Rubington, Melissa Leriche, Caroline Welsch

Cell Cycle· September 2016

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Secondary Tumors Arising in Patients Undergoing BRAF Inhibitor Therapy Exhibit Increased BRAF-CRAF Heterodimerization.
Lise Boussemart, Isabelle Girault, Hélène Malka-Mahieu, Christine Mateus, Emilie Routier

Cancer Res· March 2016

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Potential role for HIV-specific CD38-/HLA-DR+ CD8+ T cells in viral suppression and cytotoxicity in HIV controllers.
Stéphane Hua, Camille Lécuroux, Asier Sáez-Cirión, Gianfranco Pancino, Isabelle Girault

PLoS One· December 2015

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eIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies.
Lise Boussemart, Hélène Malka-Mahieu, Isabelle Girault, Delphine Allard, Oskar Hemmingsson

Nature· September 2014

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CD8 T-cells from most HIV-infected patients lack ex vivo HIV-suppressive capacity during acute and early infection.
Camille Lécuroux, Isabelle Girault, Antoine Chéret, Pierre Versmisse, Georges Nembot

PLoS One· January 2014

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Both HLA-B*57 and plasma HIV RNA levels contribute to the HIV-specific CD8+ T cell response in HIV controllers.
Camille Lécuroux, Asier Sáez-Cirión, Isabelle Girault, Pierre Versmisse, Faroudy Boufassa

J Virol· January 2014

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Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection.
Anne-Sophie Liovat, Marie-Anne Rey-Cuillé, Camille Lécuroux, Béatrice Jacquelin, Isabelle Girault

PLoS One· April 2013

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Targeting the deregulated spliceosome core machinery in cancer cells triggers mTOR blockade and autophagy.
Virginie Quidville, Samar Alsafadi, Aïcha Goubar, Frédéric Commo, Véronique Scott, Isabelle Girault

Cancer Res· April 2013

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Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study.
Asier Sáez-Cirión, Charline Bacchus, Laurent Hocqueloux, Véronique Avettand-Fenoel, Isabelle Girault

PLoS Pathog· March 2013

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HIV-1 control after transient antiretroviral treatment initiated in primary infection: role of patient characteristics and effect of therapy.
Cécile Goujard, Isabelle Girault, Christine Rouzioux, Camille Lécuroux, Christiane Deveau

Antivir Ther· January 2013

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NKG2D expression on HIV-specific CD8+ T cells is reduced in viremic HIV-1-infected patients but maintained in HIV controllers.
Camille Lecuroux, Asier Saez-Cirion, Nicolas Noel, Lilia Ben-Lamine, Isabelle Girault

J Acquir Immune Defic Syndr· January 2013

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Early and long-lasting alteration of effector CD45RA(-)Foxp3(high) regulatory T-cell homeostasis during HIV infection.
Federico Simonetta, Camille Lecuroux, Isabelle Girault, Cécile Goujard, Martine Sinet

J Infect Dis· May 2012

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Increased CD127 expression on activated FOXP3+CD4+ regulatory T cells.
Federico Simonetta, Amel Chiali, Corinne Cordier, Alejandra Urrutia, Isabelle Girault

Eur J Immunol· September 2010

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Antiretroviral therapy initiation during primary HIV infection enhances both CD127 expression and the proliferative capacity of HIV-specific CD8+ T cells.
Camille Lécuroux, Isabelle Girault, François Boutboul, Alejandra Urrutia, Cécile Goujard

AIDS· August 2009

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Identification of a particular HIV-specific CD8+ T-cell subset with a CD27+ CD45RO-/RA+ phenotype and memory characteristics after initiation of HAART during acute primary HIV infection.
Camille Lécuroux, Isabelle Girault, Alejandra Urrutia, Jean-Marc Doisne, Christiane Deveau

Blood· April 2009

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