Publications by authors named "Isabelle Mercier"

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Targeting cell-surface VISTA expression on allospecific naïve T cells promotes tolerance.
Brent H Koehn, Elizabeth C Nowak, Sladjana Skopelja-Gardner, Asim Saha, Michael C Zaiken, Isabelle Le Mercier

Blood· April 2025

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Rational design of a SOCS1-edited tumor-infiltrating lymphocyte therapy using CRISPR/Cas9 screens.
Michael R Schlabach, Sharon Lin, Zachary R Collester, Christopher Wrocklage, Sol Shenker, Isabelle Le Mercier

J Clin Invest· December 2023

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Defects in Emerin-Nucleoskeleton Binding Disrupt Nuclear Structure and Promote Breast Cancer Cell Motility and Metastasis.
Alexandra G Liddane, Chelsea A McNamara, Mallory C Campbell, Isabelle Mercier, James M Holaska

Mol Cancer Res· July 2021

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Essential role of STAT5a in DCIS formation and invasion following estrogen treatment.
Sundee Dees, Laura Pontiggia, Jean-Francois Jasmin, Federica Sotgia, Michael P Lisanti, Isabelle Mercier

Aging (Albany NY)· August 2020

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Phosphorylated STAT3 (Tyr705) as a biomarker of response to pimozide treatment in triple-negative breast cancer.
Sundee Dees, Laura Pontiggia, Jean-Francois Jasmin, Isabelle Mercier

Cancer Biol Ther· June 2020

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Development of CAPER peptides for the treatment of triple negative breast cancer.
Shannon D Chilewski, Devyani Bhosale, Sundee Dees, Isaac Hutchinson, Rachel Trimble, Isabelle Mercier

Cell Cycle· February 2020

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VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance.
Mohamed A ElTanbouly, Yanding Zhao, Elizabeth Nowak, Jiannan Li, Evelien Schaafsma, Isabelle Le Mercier

Science· January 2020

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Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment.
Jie Deng, Jiannan Li, Aurelien Sarde, J Louise Lines, Yu-Chi Lee, Isabelle Le Mercier

Cancer Immunol Res· July 2019

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CAPER as a therapeutic target for triple negative breast cancer.
Mallory C Campbell, Laura Pontiggia, Ashley Y Russell, Roland Schwarting, Jeanette Camacho, Isabelle Mercier

Oncotarget· July 2018

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Immunoregulatory functions of VISTA.
Elizabeth C Nowak, J Louise Lines, Frederick S Varn, Jie Deng, Aurelien Sarde, Isabelle Le Mercier

Immunol Rev· March 2017

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A New VISTA on combination therapy for negative checkpoint regulator blockade.
Jie Deng, Isabelle Le Mercier, Anna Kuta, Randolph J Noelle

J Immunother Cancer· December 2016

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Beyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint Regulators.
Isabelle Le Mercier, J Louise Lines, Randolph J Noelle

Front Immunol· September 2015

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CAPER, a novel regulator of human breast cancer progression.
Isabelle Mercier, Donna M Gonzales, Kevin Quann, Timothy G Pestell, Alexander Molchansky

Cell Cycle· August 2015

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Studying mast cells in peripheral tolerance by using a skin transplantation model.
Victor C de Vries, Isabelle Le Mercier, Elizabeth C Nowak, Randolph J Noelle

Methods Mol Biol· June 2015

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Caveolin-1 regulates the anti-atherogenic properties of macrophages.
Stephanos Pavlides, Jorge L Gutierrez-Pajares, Sanjay Katiyar, Jean-François Jasmin, Isabelle Mercier

Cell Tissue Res· December 2014

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Disruption of the immune-checkpoint VISTA gene imparts a proinflammatory phenotype with predisposition to the development of autoimmunity.
Li Wang, Isabelle Le Mercier, Juan Putra, Wenna Chen, Jun Liu

Proc Natl Acad Sci U S A· October 2014

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Scavenger receptor class B type I regulates cellular cholesterol metabolism and cell signaling associated with breast cancer development.
Christiane Danilo, Jorge L Gutierrez-Pajares, Maria Antonietta Mainieri, Isabelle Mercier, Michael P Lisanti

Breast Cancer Res· September 2014

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VISTA Regulates the Development of Protective Antitumor Immunity.
Isabelle Le Mercier, Wenna Chen, Janet L Lines, Maria Day, Jiannan Li

Cancer Res· April 2014

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Tumor promotion by intratumoral plasmacytoid dendritic cells is reversed by TLR7 ligand treatment.
Isabelle Le Mercier, Dominique Poujol, Amélien Sanlaville, Vanja Sisirak, Michael Gobert

Cancer Res· August 2013

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Caveolin-1 is a negative regulator of tumor growth in glioblastoma and modulates chemosensitivity to temozolomide.
Kevin Quann, Donna M Gonzales, Isabelle Mercier, Chenguang Wang, Federica Sotgia

Cell Cycle· May 2013

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Impaired IFN-α production by plasmacytoid dendritic cells favors regulatory T-cell expansion that may contribute to breast cancer progression.
Vanja Sisirak, Julien Faget, Michael Gobert, Nadège Goutagny, Nelly Vey, Isabelle Le Mercier

Cancer Res· October 2012

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Tryptophan hydroxylase-1 regulates immune tolerance and inflammation.
Elizabeth C Nowak, Victor C de Vries, Anna Wasiuk, Cory Ahonen, Kathryn A Bennett, Isabelle Le Mercier

J Exp Med· October 2012

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Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drug.
Isabelle Mercier, Jeanette Camacho, Kanani Titchen, Donna M Gonzales, Kevin Quann

Am J Pathol· July 2012

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Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis.
Stephanos Pavlides, Iset Vera, Ricardo Gandara, Sharon Sneddon, Richard G Pestell, Isabelle Mercier

Antioxid Redox Signal· June 2012

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Caveolin-1 and breast cancer: a new clinical perspective.
Isabelle Mercier, Michael P Lisanti

Adv Exp Med Biol· May 2012

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