Publications by authors named "Isabelle Rubera"

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The eIF5A hypusination inhibitor GC7 improves tolerance of pancreatic beta cells to ischemia/reperfusion.
Hajar Ouahmi, Filippo Massa, Marc Cougnon, Isabelle Rubera, Gisèle Jarretou

Am J Physiol Cell Physiol· January 2026

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Targeting seryl-tRNA synthetase to unlock ischemic resilience in stroke - Insights from a proof-of-concept study.
Miled Bourourou, Nicolas Melis, Marc Cougnon, Gilbert Laffet, Christophe Duranton, Isabelle Rubera

J Cereb Blood Flow Metab· November 2025

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Inhibition of eIF5A hypusination enhances antioxidant defense to prevent kidney Ischemia/Reperfusion injury.
Marc Cougnon, Sébastien Giraud, Maria Materozzi, Elisa Allart, Isabelle Rubera

Redox Biol· October 2025

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Proximal tubular deletion of superoxide dismutase-2 reveals disparate effects on kidney function in diabetes.
Inez A Trambas, Lilliana Bowen, Vicki Thallas-Bonke, Matthew Snelson, Karly C Sourris, Isabelle Rubera

Redox Biol· May 2025

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Correction: The PROPHECI trial: a phase II, double-blind, placebo-controlled, randomized clinical trial for the treatment of pseudoxanthoma elasticum with oral pyrophosphate.
Laetitia Clotaire, Isabelle Rubera, Christophe Duranton, Jocelyn Gal, Emmanuel Chamorey

Trials· April 2025

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The 33 Ion Channels Meeting, September 2024, Sète, France.
Valérie Coronas, Marie Demion, Ines El Bini, Adèle Faucherre, Alban Girault, Isabelle Rubera

Bioelectricity· March 2025

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The PROPHECI trial: a phase II, double-blind, placebo-controlled, randomized clinical trial for the treatment of pseudoxanthoma elasticum with oral pyrophosphate.
Laetitia Clotaire, Isabelle Rubera, Christophe Duranton, Jocelyn Gal, Emmanuel Chamorey

Trials· January 2025

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Oral pyrophosphate protects Abcc6 mice against vascular calcification induced by chronic kidney disease.
Elise Bouderlique, Jennifer Kervadec, Ellie Tang, Jeremy Zaworski, Amélie Coudert, Isabelle Rubera

J Mol Med (Berl)· October 2024

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Activation of osmo-sensitive LRRC8 anion channels in macrophages is important for micro-crystallin joint inflammation.
Twinu Wilson Chirayath, Matthias Ollivier, Mete Kayatekin, Isabelle Rubera, Chinh Nghia Pham

Nat Commun· September 2024

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A Plasma Pyrophosphate Cutoff Value for Diagnosing Pseudoxanthoma Elasticum.
Isabelle Rubera, Laetitia Clotaire, Audrey Laurain, Alexandre Destere, Ludovic Martin

Int J Mol Sci· June 2024

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The 32nd Ion Channels Meeting, 17th-20th September 2023, Sète, France.
Fabien Brette, Anna Rita Cantelmo, Valérie Coronas, Marie Demion, Ines El Bini, Isabelle Rubera

Bioelectricity· June 2024

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Renal Ischemia Tolerance Mediated by eIF5A Hypusination Inhibition Is Regulated by a Specific Modulation of the Endoplasmic Reticulum Stress.
Nicolas Melis, Isabelle Rubera, Sebastien Giraud, Marc Cougnon, Christophe Duranton

Cells· January 2023

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Arterial Calcifications in Patients with Liver Cirrhosis Are Linked to Hepatic Deficiency of Pyrophosphate Production Restored by Liver Transplantation.
Audrey Laurain, Isabelle Rubera, Micheline Razzouk-Cadet, Stéphanie Bonnafous, Miguel Albuquerque

Biomedicines· June 2022

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Relationships between Plasma Pyrophosphate, Vascular Calcification and Clinical Severity in Patients Affected by Pseudoxanthoma Elasticum.
Georges Leftheriotis, Nastassia Navasiolava, Laetitia Clotaire, Christophe Duranton, Olivier Le Saux, Isabelle Rubera

J Clin Med· May 2022

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Akt Inhibition as Preconditioning Treatment to Protect Kidney Cells against Anoxia.
Nicolas Melis, Romain Carcy, Isabelle Rubera, Marc Cougnon, Christophe Duranton

Int J Mol Sci· December 2021

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Targeted deletion of nicotinamide adenine dinucleotide phosphate oxidase 4 from proximal tubules is dispensable for diabetic kidney disease development.
Vicki Thallas-Bonke, Sih Min Tan, Runa S Lindblom, Matthew Snelson, Cesare Granata, Isabelle Rubera

Nephrol Dial Transplant· May 2021

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Proximal Tubule-Specific Deletion of Angiotensin II Type 1a Receptors in the Kidney Attenuates Circulating and Intratubular Angiotensin II-Induced Hypertension in PT- Mice.
Xiao Chun Li, Ana Paula Oliveira Leite, Xiaowen Zheng, Chunling Zhao, Xu Chen, Isabelle Rubera

Hypertension· April 2021

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LRRC8/VRAC Channels and the Redox Balance: A Complex Relationship.
Jonas Friard, Audrey Laurain, Isabelle Rubera, Christophe Duranton

Cell Physiol Biochem· March 2021

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Inhibition of eIF5A hypusination reprogrammes metabolism and glucose handling in mouse kidney.
Marc Cougnon, Romain Carcy, Nicolas Melis, Isabelle Rubera, Christophe Duranton

Cell Death Dis· March 2021

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Proximal tubular epithelial insulin receptor mediates high-fat diet-induced kidney injury.
Hak Joo Lee, Meenalakshmi M Mariappan, Luke Norton, Terry Bakewell, Denis Feliers, Isabelle Rubera

JCI Insight· February 2021

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Alkaline Phosphatases Account for Low Plasma Levels of Inorganic Pyrophosphate in Chronic Kidney Disease.
Audrey Laurain, Isabelle Rubera, Christophe Duranton, Frank Rutsch, Yvonne Nitschke

Front Cell Dev Biol· December 2020

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LRRC8/VRAC channels exhibit a noncanonical permeability to glutathione, which modulates epithelial-to-mesenchymal transition (EMT).
Jonas Friard, Alain Corinus, Marc Cougnon, Michel Tauc, Didier F Pisani, Isabelle Rubera

Cell Death Dis· December 2019

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Vitamin D and Calcium Supplementation Accelerates Randall's Plaque Formation in a Murine Model.
Elise Bouderlique, Ellie Tang, Joëlle Perez, Amélie Coudert, Dominique Bazin, Isabelle Rubera

Am J Pathol· November 2019

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Proximal Tubule-Specific Deletion of the NHE3 (Na/H Exchanger 3) in the Kidney Attenuates Ang II (Angiotensin II)-Induced Hypertension in Mice.
Xiao C Li, Dongmin Zhu, Xu Chen, Xiaowen Zheng, Chunling Zhao, Isabelle Rubera

Hypertension· September 2019

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TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells.
Malika Arhatte, Gihan S Gunaratne, Charbel El Boustany, Ivana Y Kuo, Céline Moro, Isabelle Rubera

Nat Commun· May 2019

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