Publications by authors named "Ishak D Irwan"

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Activating PKC-ε induces HIV expression with improved tolerability.
Alivelu M Irrinki, Jasmine Kaur, Bally Randhawa, Ryan McFadden, Chelsea Snyder, Ishak Darryl Irwan

PLoS Pathog· February 2025

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The SMC5/6 complex: An emerging antiviral restriction factor that can silence episomal DNA.
Ishak D Irwan, Bryan R Cullen

PLoS Pathog· March 2023

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Epigenetic silencing by the SMC5/6 complex mediates HIV-1 latency.
Ishak D Irwan, Hal P Bogerd, Bryan R Cullen

Nat Microbiol· December 2022

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Tax Induces the Recruitment of NF-κB to Unintegrated HIV-1 DNA To Rescue Viral Gene Expression and Replication.
Ishak D Irwan, Bryan R Cullen

J Virol· June 2021

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Validation study of HLA-B*13:01 as a biomarker of dapsone hypersensitivity syndrome in leprosy patients in Indonesia.
Hana Krismawati, Astrid Irwanto, Arry Pongtiku, Ishak Darryl Irwan, Yustinus Maladan

PLoS Negl Trop Dis· October 2020

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Reversal of Epigenetic Silencing Allows Robust HIV-1 Replication in the Absence of Integrase Function.
Ishak D Irwan, Heather L Karnowski, Hal P Bogerd, Kevin Tsai, Bryan R Cullen

mBio· June 2020

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Insights into the mechanisms underlying the inactivation of HIV-1 proviruses by CRISPR/Cas.
Adam L Mefferd, Hal P Bogerd, Ishak D Irwan, Bryan R Cullen

Virology· July 2018

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Genome-wide association study of Parkinson's disease in East Asians.
Jia Nee Foo, Louis C Tan, Ishak D Irwan, Wing-Lok Au, Hui Qi Low

Hum Mol Genet· January 2017

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Linking a genome-wide association study signal to a LRRK2 coding variant in Parkinson's disease.
Jia Nee Foo, Sun Ju Chung, Louis C Tan, Herty Liany, Ho-Sung Ryu, Ishak D Irwan

Mov Disord· April 2016

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Identification of new susceptibility loci for IgA nephropathy in Han Chinese.
Ming Li, Jia-Nee Foo, Jin-Quan Wang, Hui-Qi Low, Xue-Qing Tang, Ishak D Irwan

Nat Commun· June 2015

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Genome-wide linkage, exome sequencing and functional analyses identify ABCB6 as the pathogenic gene of dyschromatosis universalis hereditaria.
Hong Liu, Yi Li, Ken Kwok Hon Hung, Na Wang, Chuan Wang, Ishak Darryl Irwan

PLoS One· December 2014

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Analysis of non-synonymous-coding variants of Parkinson's disease-related pathogenic and susceptibility genes in East Asian populations.
Jia Nee Foo, Louis C Tan, Herty Liany, Tat Hung Koh, Ishak D Irwan

Hum Mol Genet· July 2014

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Coding variants at hexa-allelic amino acid 13 of HLA-DRB1 explain independent SNP associations with follicular lymphoma risk.
Jia Nee Foo, Karin E Smedby, Nicholas K Akers, Mattias Berglund, Ishak D Irwan

Am J Hum Genet· July 2013

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The association between rare large duplication of 16p11.2 and schizophrenia in the Singaporean Chinese population.
Xuebin Zheng, Jin-Xin Bei, Haiyan Xu, Jimmy Lee, Siow-Ann Chong, Ishak D Irwan

Schizophr Res· May 2013

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GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma.
Karin E Smedby, Jia Nee Foo, Christine F Skibola, Hatef Darabi, Lucia Conde, Ishak D Irwan

PLoS Genet· April 2011

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Isthmin is a novel secreted angiogenesis inhibitor that inhibits tumour growth in mice.
Wei Xiang, Zhiyuan Ke, Yong Zhang, Grace Ho-Yuet Cheng, Ishak Darryl Irwan

J Cell Mol Med· February 2011

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