Publications by authors named "Isobel D Stewart"

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Plasma Metabolite N-Formylmethionine Is Associated With Higher Blood Pressure in the Multiethnic HELIUS Cohort and Triggers Vascular Dysfunction.
Barbara J H Verhaar, Nadia Romp, Charlotte M Mosterd, Tien T Nguyen, Vanasa Nageswaran, Isobel D Stewart

Hypertension· November 2025

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Testing for a causal role of thyroid hormone measurements within the normal range on human metabolism and diseases: a systematic Mendelian randomization.
Heba Alwan, Jian'an Luan, Alice Williamson, Julia Carrasco-Zanini, Isobel D Stewart

EBioMedicine· September 2024

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Plasma Metabolites Related to the Consumption of Different Types of Dairy Products and Their Association with New-Onset Type 2 Diabetes: Analyses in the Fenland and EPIC-Norfolk Studies, United Kingdom.
Eirini Trichia, Albert Koulman, Isobel D Stewart, Soren Brage, Simon J Griffin

Mol Nutr Food Res· January 2024

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Circulating metabolites modulated by diet are associated with depression.
Ashley van der Spek, Isobel D Stewart, Brigitte Kühnel, Maik Pietzner, Tahani Alshehri

Mol Psychiatry· September 2023

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Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation study.
Jian Zhao, Isobel D Stewart, Denis Baird, Dan Mason, John Wright

EBioMedicine· February 2023

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Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.
Yiheng Chen, Tianyuan Lu, Ulrika Pettersson-Kymmer, Isobel D Stewart, Guillaume Butler-Laporte

Nat Genet· January 2023

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Rare and common genetic determinants of metabolic individuality and their effects on human health.
Praveen Surendran, Isobel D Stewart, Victoria P W Au Yeung, Maik Pietzner, Johannes Raffler

Nat Med· November 2022

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Metabolomic differences in lung function metrics: evidence from two cohorts.
Rachel S Kelly, Isobel D Stewart, Haley Bayne, Priyadarshini Kachroo, Avron Spiro

Thorax· September 2022

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Development and validation of a metabolite score for red meat intake: an observational cohort study and randomized controlled dietary intervention.
Chunxiao Li, Fumiaki Imamura, Roland Wedekind, Isobel D Stewart, Maik Pietzner

Am J Clin Nutr· August 2022

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Author Correction: Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma.
Priyadarshini Kachroo, Isobel D Stewart, Rachel S Kelly, Meryl Stav, Kevin Mendez

Nat Med· August 2022

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The Relationship of Maternal Gestational Mass Spectrometry-Derived Metabolites with Offspring Congenital Heart Disease: Results from Multivariable and Mendelian Randomization Analyses.
Kurt Taylor, Nancy McBride, Jian Zhao, Sam Oddie, Rafaq Azad, Isobel D Stewart

J Cardiovasc Dev Dis· July 2022

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Whole-exome sequencing identifies rare genetic variants associated with human plasma metabolites.
Lorenzo Bomba, Klaudia Walter, Qi Guo, Praveen Surendran, Kousik Kundu, Isobel D Stewart

Am J Hum Genet· June 2022

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Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma.
Priyadarshini Kachroo, Isobel D Stewart, Rachel S Kelly, Meryl Stav, Kevin Mendez

Nat Med· April 2022

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Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution.
Mine Koprulu, Yajie Zhao, Eleanor Wheeler, Liang Dong, Nuno Rocha, Isobel D Stewart

J Clin Endocrinol Metab· March 2022

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Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the Region.
Nicholas Bowker, Robert Hansford, Stephen Burgess, Christopher N Foley, Victoria P W Auyeung, Isobel D Stewart

Diabetes· November 2021

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Mapping the proteo-genomic convergence of human diseases.
Maik Pietzner, Eleanor Wheeler, Julia Carrasco-Zanini, Adrian Cortes, Mine Koprulu, Isobel D Stewart

Science· November 2021

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Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study.
Aayah Nounu, Rebecca C Richmond, Isobel D Stewart, Praveen Surendran, Nicholas J Wareham

Nutrients· November 2021

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Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases.
Na Cai, Aurora Gomez-Duran, Ekaterina Yonova-Doing, Kousik Kundu, Annette I Burgess, Isobel D Stewart

Nat Med· September 2021

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The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium.
Florence Guida, Vanessa Y Tan, Laura J Corbin, Karl Smith-Byrne, Karine Alcala, Isobel D Stewart

PLoS Med· September 2021

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The trans-ancestral genomic architecture of glycemic traits.
Ji Chen, Cassandra N Spracklen, Gaëlle Marenne, Arushi Varshney, Laura J Corbin, Isobel D Stewart

Nat Genet· June 2021

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Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.
Praveen Surendran, Elena V Feofanova, Najim Lahrouchi, Ioanna Ntalla, Savita Karthikeyan, Isobel D Stewart

Nat Genet· May 2021

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Plasma metabolites to profile pathways in noncommunicable disease multimorbidity.
Maik Pietzner, Isobel D Stewart, Johannes Raffler, Kay-Tee Khaw, Gregory A Michelotti

Nat Med· March 2021

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Plasma Vitamin C and Type 2 Diabetes: Genome-Wide Association Study and Mendelian Randomization Analysis in European Populations.
Ju-Sheng Zheng, Jian'an Luan, Eleni Sofianopoulou, Fumiaki Imamura, Isobel D Stewart

Diabetes Care· January 2021

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A cross-platform approach identifies genetic regulators of human metabolism and health.
Luca A Lotta, Maik Pietzner, Isobel D Stewart, Laura B L Wittemans, Chen Li

Nat Genet· January 2021

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Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.
Praveen Surendran, Elena V Feofanova, Najim Lahrouchi, Ioanna Ntalla, Savita Karthikeyan, Isobel D Stewart

Nat Genet· December 2020

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