Publications by authors named "Issam Hamadeh"

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Plasma cell identity escape drives resistance to anti-BCMA T-cell-redirecting therapy in multiple myeloma.
Francesco Maura, Ciara L Freeman, Kylee H Maclachlan, Marta Larrayoz Ilundain, Bachisio Ziccheddu, Issam Hamadeh

bioRxiv· December 2025

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Cytomegalovirus reactivation during treatment with bispecific antibodies for relapsed/refractory multiple myeloma.
Eric Jurgens, Tala Shekarkhand, Colin Rueda, David Nemirovsky, Andriy Derkach, Issam Hamadeh

Blood Cancer J· November 2025

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Defining the Rates of Cytokine Release Syndrome Associated With Talquetamab Step-up Doses.
Issam S Hamadeh, Lisa Modelevsky, Amelia Chan, Aaron Mitchell, Ross S Firestone

JCO Oncol Pract· September 2025

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Outcomes in frail patients receiving BCMA-directed bispecific antibodies for relapsed/refractory multiple myeloma.
Benjamin Adegbite, Carlyn Rose Tan, Tala Shekarkhand, Ross S Firestone, Eric M Jurgens, Issam S Hamadeh

Blood Adv· August 2025

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Restarting teclistamab and talquetamab after prolonged dose delay may not require re-step-up dosing.
Carlyn Rose Tan, Alice Wang, David Nemirovsky, Andriy Derkach, Tala Shekarkhand, Issam Hamadeh

Blood Adv· July 2025

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Perspectives on Talquetamab and its Utility in the Treatment of Multiple Myeloma: Safety, Efficacy and Place in Therapy.
Kevin C Miller, Issam Hamadeh, Carlyn Rose Tan

Cancer Manag Res· April 2025

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Hematocrit control and thrombotic risk in patients with polycythemia vera treated with ruxolitinib in clinical practice.
Aleksander Chojecki, Danielle Boselli, Allison Dortilus, Issam Hamadeh, Stephanie Begley

Ann Hematol· August 2024

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Chimeric antigen receptor T-cells: a review on current status and future directions for relapsed/refractory multiple myeloma.
Issam S Hamadeh, Reed Friend, Sham Mailankody, Shebli Atrash

Front Oncol· August 2024

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Patterns of CRS with teclistamab in relapsed/refractory multiple myeloma with or without prior T-cell redirection therapy.
Issam S Hamadeh, Tala Shekarkhand, Colin Rueda, Ross S Firestone, Alice X Wang

Blood Adv· June 2024

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Unscheduled health care interactions in patients with multiple myeloma receiving T-cell redirection therapies.
Anna J Howard, Isabel Concepcion, Alice X Wang, Issam S Hamadeh, Malin Hultcrantz

Blood Adv· June 2024

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CD8 effector T cells enhance teclistamab response in BCMA-exposed and -naïve multiple myeloma.
Ross S Firestone, Devin McAvoy, Tala Shekarkhand, Edith Serrano, Issam Hamadeh

Blood Adv· April 2024

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Genetic Predictors of Ibrutinib-related Cardiovascular Side Effects in Patients with Chronic Lymphocytic Leukemia.
Issam S Hamadeh, Jai N Patel, Ryan Jacobs, Hang Zeng, Jiaxian He

Clin Cancer Res· December 2023

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Genome-wide Association Study Identified Chromosome 8 Locus Associated with Medication-Related Osteonecrosis of the Jaw.
Guang Yang, Sonal Singh, Caitrin W McDonough, Jatinder K Lamba, Issam Hamadeh

Clin Pharmacol Ther· December 2021

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Potentially actionable pharmacogenetic variants and symptom control medications in oncology.
Jai N Patel, Danielle Boselli, Elizabeth J Jandrisevits, Issam S Hamadeh, Ahmed Salem

Support Care Cancer· October 2021

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Transition from Intravenous to Subcutaneous Daratumumab Formulation in Clinical Practice.
Issam S Hamadeh, Donald C Moore, Allison Martin, Allison Karabinos, Hailey Hill

Clin Lymphoma Myeloma Leuk· July 2021

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Phase 2 study of the safety and efficacy of umbralisib in patients with CLL who are intolerant to BTK or PI3Kδ inhibitor therapy.
Anthony R Mato, Nilanjan Ghosh, Stephen J Schuster, Nicole Lamanna, John M Pagel, Issam S Hamadeh

Blood· May 2021

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Single-center experience with use of letermovir for treatment of CMV infection in stem cell transplant recipients.
Ekaterina Kachur, Danya Roshdy, Issam Hamadeh, Brandy Dodd, Zainab Shahid

Transpl Infect Dis· April 2021

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Implications of Polymorphisms in the BCKDK and GATA-4 Gene Regions on Stable Warfarin Dose in African Americans.
Salma A Bargal, Jennifer N Kight, Felipe Augusto de Oliveira, Mohamed H Shahin, Taimour Langaee, Issam S Hamadeh

Clin Transl Sci· March 2021

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North Carolina's multi-institutional pharmacogenomics efforts with the North Carolina Precision Health Collaborative.
Jai N Patel, Deepak Voora, Gillian Bell, Jill Bates, Amber Cipriani, Issam Hamadeh

Pharmacogenomics· January 2021

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Pharmacogenomics-guided opioid management.
Jai N Patel, Issam S Hamadeh

BMJ Support Palliat Care· December 2020

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Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype-Derived Activity Scores.
Cameron D Thomas, Scott A Mosley, Sarah Kim, Karthik Lingineni, Nihal El Rouby, Issam S Hamadeh

CPT Pharmacometrics Syst Pharmacol· December 2020

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Daratumumab subcutaneous formulation for the treatment of multiple myeloma.
Barry Paul, Issam Hamadeh, Shebli Atrash, Manisha Bhutani, Peter Voorhees

Expert Opin Biol Ther· November 2020

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Safety and Cost Benefits of the Rapid Daratumumab Infusion Protocol.
Issam S Hamadeh, Emily S Reese, Justin R Arnall, Ekaterina Kachur, Allison L Martin

Clin Lymphoma Myeloma Leuk· August 2020

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An evaluation of subcutaneous daratumumab for the treatment of multiple myeloma.
Barry Paul, Shebli Atrash, Manisha Bhutani, Peter Voorhees, Issam Hamadeh

Expert Rev Hematol· August 2020

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Pharmacogenetics and tacrolimus administration in stem cell transplantation.
Jai N Patel, Issam S Hamadeh

Pharmacogenomics· April 2020

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