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Publications by authors named "Issam Senoussi"

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Disruption of protein-protein interaction hotspots in the C-terminal domain of MLH1 confers mismatch repair deficiency.
Keri M Fishwick, Diego Gomez Vieito, Giada Greco, Giulio Collotta, Marco Gatti, Issam Senoussi

NAR Cancer· December 2025


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Mechanism of trinucleotide repeat expansion by MutSβ-MutLγ and contraction by FAN1.
Issam Senoussi, Valentina Mengoli, Arianna Cerana, Andrea Rinaldi, Andrés Marco

Nat Commun· October 2025


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EXO1 promotes the meiotic MLH1-MLH3 endonuclease through conserved interactions with MLH1, MSH4 and DNA.
Megha Roy, Aurore Sanchez, Raphael Guerois, Issam Senoussi, Arianna Cerana

Nat Commun· May 2025


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An E3 ubiquitin ligase localization screen uncovers DTX2 as a novel ADP-ribosylation-dependent regulator of DNA double-strand break repair.
Billel Djerir, Isabelle Marois, Jean-Christophe Dubois, Steven Findlay, Théo Morin, Issam Senoussi

J Biol Chem· August 2024


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