Publications by authors named "Issei Shimada"

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Validation of the European Society of Cardiology 0/1-hour algorithm for chest pain triage in Asian emergency departments: a multinational stepped-wedge cluster-randomised trial.
Kenji Inoue, Raphael Twerenbold, Sazzli Kasim, Farina Mohd Salleh, Ahmad Suhailan Mohamed, Issei Shimada

Heart· November 2025

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Aberrant activation of IL-6/JAK/STAT3/FOSL1 signaling induces renal abnormalities in a Xenopus model of Joubert syndrome-related disorders.
Udval Uuganbayar, Hiromasa Ninomiya, Issei S Shimada, Chisato Yamada, Mayu Kanie

J Biol Chem· August 2025

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Biallelic null variants in PNPLA8 cause microcephaly by reducing the number of basal radial glia.
Yuji Nakamura, Issei S Shimada, Reza Maroofian, Micol Falabella, Maha S Zaki

Brain· November 2024

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Transcription Factor 23 is an Essential Determinant of Murine Term Parturition.
Fatma M Minisy, Hossam H Shawki, Tsubasa Fujita, Ahmed M Moustafa, Rumeysa Sener, Issei S Shimada

Mol Cell Biol· July 2024

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The binding of LARP6 and DNAAF6 in biomolecular condensates influences ciliogenesis of multiciliated cells.
Ryan Earwood, Hiromasa Ninomiya, Hao Wang, Issei S Shimada, Mia Stroud

J Biol Chem· June 2024

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Phagocytosis model of calcium oxalate monohydrate crystals generated using human induced pluripotent stem cell-derived macrophages.
Tomoki Okada, Atsushi Okada, Hiromasa Aoki, Daichi Onozato, Taiki Kato, Issei S Shimada

Urolithiasis· March 2024

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Correction: An international, stepped wedge, cluster-randomized trial investigating the 0/1-h algorithm in suspected acute coronary syndrome in Asia: the rational of the DROP-Asian ACS study.
Kenji Inoue, Jack Tan Wei Chieh, Lim Chiw Yeh, Shuo-Ju Chiang, Arintaya Phrommintikul, Issei Shimada

Trials· May 2023

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Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia.
Vivek Reddy Palicharla, Sun-Hee Hwang, Bandarigoda N Somatilaka, Emilie Legué, Issei S Shimada

Mol Biol Cell· March 2023

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An international, stepped wedge, cluster-randomized trial investigating the 0/1-h algorithm in suspected acute coronary syndrome in Asia: the rational of the DROP-Asian ACS study.
Kenji Inoue, Jack Tan Wei Chieh, Lim Chiw Yeh, Shuo-Ju Chiang, Arintaya Phrommintikul, Issei Shimada

Trials· December 2022

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Ciliary signaling in stem cells in health and disease: Hedgehog pathway and beyond.
Issei S Shimada, Yoichi Kato

Semin Cell Dev Biol· September 2022

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Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities.
Issei S Shimada, Bandarigoda N Somatilaka, Sun-Hee Hwang, Ashley G Anderson, John M Shelton

Dev Biol· June 2019

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Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.
Issei S Shimada, Sun-Hee Hwang, Bandarigoda N Somatilaka, Xin Wang, Patryk Skowron

Cell Rep· January 2018

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Prdm16 is required for the maintenance of neural stem cells in the postnatal forebrain and their differentiation into ependymal cells.
Issei S Shimada, Melih Acar, Rebecca J Burgess, Zhiyu Zhao, Sean J Morrison

Genes Dev· June 2017

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Using Primary Neurosphere Cultures to Study Primary Cilia.
Issei S Shimada, Hemant Badgandi, Bandarigoda N Somatilaka, Saikat Mukhopadhyay

J Vis Exp· April 2017

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Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.
Hemant B Badgandi, Sun-Hee Hwang, Issei S Shimada, Evan Loriot, Saikat Mukhopadhyay

J Cell Biol· March 2017

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G-protein-coupled receptor signaling and neural tube closure defects.
Issei S Shimada, Saikat Mukhopadhyay

Birth Defects Res· January 2017

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Trafficking to the primary cilium membrane.
Saikat Mukhopadhyay, Hemant B Badgandi, Sun-Hee Hwang, Bandarigoda Somatilaka, Issei S Shimada

Mol Biol Cell· January 2017

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Leptin Receptor Promotes Adipogenesis and Reduces Osteogenesis by Regulating Mesenchymal Stromal Cells in Adult Bone Marrow.
Rui Yue, Bo O Zhou, Issei S Shimada, Zhiyu Zhao, Sean J Morrison

Cell Stem Cell· June 2016

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Notch1-STAT3-ETBR signaling axis controls reactive astrocyte proliferation after brain injury.
Matthew D LeComte, Issei S Shimada, Casey Sherwin, Jeffrey L Spees

Proc Natl Acad Sci U S A· July 2015

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Self-renewal and differentiation of reactive astrocyte-derived neural stem/progenitor cells isolated from the cortical peri-infarct area after stroke.
Issei S Shimada, Matthew D LeComte, Jerrica C Granger, Noah J Quinlan, Jeffrey L Spees

J Neurosci· June 2012

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Proliferating reactive astrocytes are regulated by Notch-1 in the peri-infarct area after stroke.
Issei S Shimada, Alyssa Borders, Alexander Aronshtam, Jeffrey L Spees

Stroke· November 2011

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SDF-1α secreted by human CD133-derived multipotent stromal cells promotes neural progenitor cell survival through CXCR7.
Benjamin Bakondi, Issei S Shimada, Brittni M Peterson, Jeffrey L Spees

Stem Cells Dev· June 2011

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Stem and progenitor cells for neurological repair: minor issues, major hurdles, and exciting opportunities for paracrine-based therapeutics.
Issei S Shimada, Jeffrey L Spees

J Cell Biochem· February 2011

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Isolation of locally derived stem/progenitor cells from the peri-infarct area that do not migrate from the lateral ventricle after cortical stroke.
Issei S Shimada, Brittni M Peterson, Jeffrey L Spees

Stroke· September 2010

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CD133 identifies a human bone marrow stem/progenitor cell sub-population with a repertoire of secreted factors that protect against stroke.
Benjamin Bakondi, Issei S Shimada, Anthony Perry, James R Munoz, Joni Ylostalo

Mol Ther· November 2009

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