Publications by authors named "Ivan Rusyn"

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An in vitro-in silico workflow for predicting renal clearance of environmental chemicals and drugs.
Courtney Sakolish, Hsing-Chieh Lin, Haley L Moyer, Lucie C Ford, Charles H Christen, Ivan Rusyn

Toxicology· January 2026

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Exploring the potential of liver microphysiological systems of varied configurations to model cholestatic chemical effects.
Katharina S Nitsche, Courtney Sakolish, Paul L Carmichael, Philip Hewitt, Piyush Bajaj, Ivan Rusyn

Arch Toxicol· December 2025

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Mediation analysis of the molecular phenotypes in a severe MASH-like liver injury mouse model.
Zhuolin Song, Volodymyr P Tryndyak, Rose A Willett, Igor P Pogribny, Ivan Rusyn

Toxicol Sci· November 2025

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Fetal response to maternal exposures of environmental chemicals: Utility of a four-cell human feto-maternal interface organ-on-chip.
Haley L Moyer, SungJin Kim, Bowie P Lam, Lauren S Richardson, Han-Hsuan D Tsai, Ivan Rusyn

Chem Biol Interact· November 2025

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Comparative Analysis of Species-Specific Hepatocyte Function and Drug Effects in a Liver Microphysiological System PhysioMimix LC12 and 96-Well Plates.
Chander K Negi, Courtney Sakolish, Han-Hsuan D Tsai, Katharina Nitsche, Han Gang, Ivan Rusyn

ACS Pharmacol Transl Sci· November 2025

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Strain and Sex Variability in Liver, Kidney and Lung Levels of DNA Adducts EB-GII and -N7G-BD Following Inhalation Exposure to 1,3-Butadiene in Collaborative Cross Mice.
Erik Moran, Samantha Goodman, Fred A Wright, Richard Evans, Natalia Y Tretyakova, Ivan Rusyn

Toxics· October 2025

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ToxPoint: Of hammers and nails-understanding academic challenges with "context of use" and "fit for purpose".
Ivan Rusyn

Toxicol Sci· September 2025

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Signature gene expression model for quantitative evaluation of MASH-like liver injury in mice.
Volodymyr P Tryndyak, Rose A Willett, Zhuolin Song, Kostiantyn Dreval, Jennifer M Hughes Hanks, Ivan Rusyn

Toxicol Appl Pharmacol· September 2025

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Derivation of ultrasound and electrocardiogram cardiac reference ranges for Mus musculus using the collaborative cross and identification of new cardiac models.
Julia L Popp, Krishna Patel, Danila Cuomo, Rachel M Lynch, Steve W Leung, Ivan Rusyn

BMC Cardiovasc Disord· September 2025

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Reference library for suspect screening of environmental toxicants using ion mobility spectrometry-mass spectrometry.
Devin Teri, Noor A Aly, James N Dodds, Jian Zhang, Paul A Thiessen, Ivan Rusyn

Commun Chem· August 2025

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Design and Enzyme-Targeted Assessment of 1,2,4-Triazole-1,8-Naphthalimide Hybrids in Drug Discovery.
Nataliya Korol, Mykhailo Slyvka, Ivan Rusyn, Oleksandra Pallah, Svitlana Burmei

Biomed Res Int· August 2025

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Evaluating Ion Mobility Data Acquisition, Calibration, and Processing for Small Molecules: A Cross-Platform Assessment of Drift Tube and Traveling Wave Methodologies.
James N Dodds, Lucie C Ford, Jack P Ryan, Amie M Solosky, Ivan Rusyn

J Am Soc Mass Spectrom· July 2025

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An approach to uncover significant direct and mediated relationships in multi-dimensional new approach methods (NAMs) data: A case study of hazard evaluation of petroleum UVCBs.
Yi-Hui Zhou, Paul J Gallins, Ivan Rusyn, Fred A Wright

Sci Total Environ· July 2025

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What does "success" look like in compliance check decisions by the European Chemicals Agency? The curious cases of accepted read-across adaptations.
Hannah M Roe, Han-Hsuan D Tsai, Nicholas Ball, King D Oware, Gang Han, Ivan Rusyn

ALTEX· July 2025

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Human Small Intestinal Tissue Models to Assess Barrier Permeability: Comparative Analysis of Caco-2 Cells, Jejunal and Duodenal Enteroid-Derived Cells, and EpiIntestinal Tissues in Membrane-Based Cultures with and Without Flow.
Haley L Moyer, Leoncio Vergara, Clifford Stephan, Courtney Sakolish, Hsing-Chieh Lin, Ivan Rusyn

Bioengineering (Basel)· July 2025

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A workflow for human health hazard evaluation using transcriptomic data and Key Characteristics-based gene sets.
Han-Hsuan D Tsai, King D Oware, Fred A Wright, Weihsueh A Chiu, Ivan Rusyn

Toxicol Sci· June 2025

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MyEcoReporter: a prototype for artificial intelligence-facilitated pollution reporting.
Weihsueh A Chiu, Galen Newman, Garett Sansom, Xinyue Ye, Andriy Rusyn, Ivan Rusyn

J Expo Sci Environ Epidemiol· May 2025

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Comparative Analysis of Chemical Distribution Models for Quantitative In Vitro to In Vivo Extrapolation.
Hsing-Chieh Lin, Lucie C Ford, Ivan Rusyn, Weihsueh A Chiu

Toxics· May 2025

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Examining risk assessment implications of genetic and dose-dependent dynamics of lead exposure in breastfeeding using the collaborative cross mouse population.
Danila Cuomo, Zhuolin Song, Megan Nitcher, Rachel Lynch, Estefania Barba, Ivan Rusyn

Toxicol Sci· April 2025

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Comparative analysis of Caco-2 cells and human jejunal and duodenal enteroid-derived cells in gel- and membrane-based barrier models of intestinal permeability.
Haley L Moyer, Leoncio Vergara, Clifford Stephan, Courtney Sakolish, Lucie C Ford, Ivan Rusyn

Toxicol Sci· April 2025

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Mobile air monitoring to identify volatile organic compound distributions and potential hazard during the remediation of the East Palestine, Ohio train derailment.
Mariana Saitas, Toriq Mustapha, Eva Vitucci, Oladayo Oladeji, Han-Hsuan D Tsai, Ivan Rusyn

Environ Monit Assess· April 2025

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Reference Library for Suspect Non-targeted Screening of Environmental Toxicants Using Ion Mobility Spectrometry-Mass Spectrometry.
Devin Teri, Noor A Aly, James N Dodds, Jian Zhang, Paul A Thiessen, Ivan Rusyn

bioRxiv· February 2025

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Comparative Analysis of Proximal Tubule Cell Sources for In Vitro Studies of Renal Proximal Tubule Toxicity.
Courtney Sakolish, Han-Hsuan D Tsai, Hsing-Chieh Lin, Piyush Bajaj, Remi Villenave, Ivan Rusyn

Biomedicines· February 2025

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Multidimensional library for the improved identification of per- and polyfluoroalkyl substances (PFAS).
Kara M Joseph, Anna K Boatman, James N Dodds, Kaylie I Kirkwood-Donelson, Jack P Ryan, Ivan Rusyn

Sci Data· January 2025

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Comparative analysis of the physiological and transport functions of various sources of renal proximal tubule cells under static and fluidic conditions in PhysioMimix T12 platform.
Courtney Sakolish, Haley L Moyer, Han-Hsuan D Tsai, Lucie C Ford, Allison N Dickey, Ivan Rusyn

Drug Metab Dispos· January 2025

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