Publications by authors named "Ivars Silamikelis"

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Dual-approach analysis of gut microbiome in patients with type 1 diabetes and diabetic kidney disease.
Laura Bunka, Maija Rozenberga, Ivars Silamiķelis, Rihards Saksis, Līga Birzniece

Ann Med· December 2025

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Bacterial targets of fecal host miRNAs in high-fat diet-fed mice.
Laila Silamiķele, Ivars Silamiķelis, Patrīcija Paulīne Kotoviča, Jānis Kloviņš

PLoS One· May 2025

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Gut microbiome encoded purine and amino acid pathways present prospective biomarkers for predicting metformin therapy efficacy in newly diagnosed T2D patients.
Ilze Elbere, Zigmunds Orlovskis, Laura Ansone, Ivars Silamikelis, Lauma Jagare

Gut Microbes· June 2024

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Gut Microbiome Composition and Dynamics in Hospitalized COVID-19 Patients and Patients with Post-Acute COVID-19 Syndrome.
Monta Brīvība, Laila Silamiķele, Līga Birzniece, Laura Ansone, Kaspars Megnis

Int J Mol Sci· January 2024

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Evaluating the Efficacy of Type 2 Diabetes Polygenic Risk Scores in an Independent European Population.
Monta Brīvība, Ivanna Atava, Raitis Pečulis, Ilze Elbere, Laura Ansone

Int J Mol Sci· January 2024

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Ryegrass mottle virus complete genome determination and development of infectious cDNA by combining two methods- 3' RACE and RNA-Seq.
Ina Balke, Ivars Silamikelis, Ilze Radovica-Spalvina, Vilija Zeltina, Gunta Resevica

PLoS One· December 2023

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Metformin targets intestinal immune system signaling pathways in a high-fat diet-induced mouse model of obesity and insulin resistance.
Monta Brīvība, Laila Silamiķele, Ineta Kalniņa, Ivars Silamiķelis, Līga Birzniece

Front Endocrinol (Lausanne)· November 2023

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Whole-Genome Sequencing of 502 Individuals from Latvia: The First Step towards a Population-Specific Reference of Genetic Variation.
Raimonds Reščenko, Monta Brīvība, Ivanna Atava, Vita Rovīte, Raitis Pečulis

Int J Mol Sci· October 2023

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Variations in the Relative Abundance of Gut Bacteria Correlate with Lipid Profiles in Healthy Adults.
Ineta Kalnina, Dita Gudra, Ivars Silamikelis, Kristine Viksne, Ance Roga

Microorganisms· October 2023

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Abundance and prevalence of ESBL coding genes in patients undergoing first line eradication therapy for Helicobacter pylori.
Dita Gudra, Ivars Silamikelis, Janis Pjalkovskis, Ilva Danenberga, Darta Pupola

PLoS One· August 2023

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Metatranscriptome analysis of blood in healthy individuals and irritable bowel syndrome patients.
Lauma Jagare, Maija Rozenberga, Ivars Silamikelis, Laura Ansone, Ilze Elbere

J Med Microbiol· June 2023

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Spatial variation of the gut microbiome in response to long-term metformin treatment in high-fat diet-induced type 2 diabetes mouse model of both sexes.
Laila Silamiķele, Rihards Saksis, Ivars Silamiķelis, Patrīcija Paulīne Kotoviča, Monta Brīvība

Gut Microbes· March 2023

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OverFlap PCR: A reliable approach for generating plasmid DNA libraries containing random sequences without a template bias.
Artis Linars, Ivars Silamikelis, Dita Gudra, Ance Roga, Davids Fridmanis

PLoS One· August 2022

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Metformin Strongly Affects Gut Microbiome Composition in High-Fat Diet-Induced Type 2 Diabetes Mouse Model of Both Sexes.
Laila Silamiķele, Ivars Silamiķelis, Monta Ustinova, Zane Kalniņa, Ilze Elbere

Front Endocrinol (Lausanne)· December 2021

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Amino Acid Metabolism is Significantly Altered at the Time of Admission in Hospital for Severe COVID-19 Patients: Findings from Longitudinal Targeted Metabolomics Analysis.
Laura Ansone, Monta Briviba, Ivars Silamikelis, Anna Terentjeva, Ingus Perkons

Microbiol Spectr· December 2021

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First Report on the Latvian SARS-CoV-2 Isolate Genetic Diversity.
Nikita Zrelovs, Monta Ustinova, Ivars Silamikelis, Liga Birzniece, Kaspars Megnis

Front Med (Lausanne)· April 2021

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Medication for Acromegaly Reduces Expression of MUC16, MACC1 and GRHL2 in Pituitary Neuroendocrine Tumour Tissue.
Rihards Saksis, Ivars Silamikelis, Pola Laksa, Kaspars Megnis, Raitis Peculis

Front Oncol· February 2021

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Baseline gut microbiome composition predicts metformin therapy short-term efficacy in newly diagnosed type 2 diabetes patients.
Ilze Elbere, Ivars Silamikelis, Ilze Izabella Dindune, Ineta Kalnina, Monta Briviba

PLoS One· December 2020

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Whole-blood transcriptome profiling reveals signatures of metformin and its therapeutic response.
Monta Briviba, Laura Ansone, Ivars Silamikelis, Vita Rovite, Ilze Elbere

PLoS One· October 2020

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Metformin strongly affects transcriptome of peripheral blood cells in healthy individuals.
Monta Briviba, Ivars Silamikelis, Ineta Kalnina, Laura Ansone, Vita Rovite

PLoS One· March 2020

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Case report: recurrent pituitary adenoma has increased load of somatic variants.
Raitis Peculis, Inga Balcere, Ilze Radovica-Spalvina, Ilze Konrade, Olivija Caune, Ivars Silamikelis

BMC Endocr Disord· January 2020

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A widely used sampling device in colorectal cancer screening programmes allows for large-scale microbiome studies.
Dita Gudra, Saeed Shoaie, Davids Fridmanis, Janis Klovins, Hugo Wefer, Ivars Silamikelis

Gut· September 2019

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Association of metformin administration with gut microbiome dysbiosis in healthy volunteers.
Ilze Elbere, Ineta Kalnina, Ivars Silamikelis, Ilze Konrade, Linda Zaharenko

PLoS One· March 2019

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Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals.
Ilze Elbere, Ivars Silamikelis, Monta Ustinova, Ineta Kalnina, Linda Zaharenko

Clin Epigenetics· December 2018

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Gene expression profiling of fast- and slow-growing non-functioning gonadotroph pituitary adenomas.
Camilla Maria Falch, Arvind Y M Sundaram, Kristin Astrid Øystese, Kjersti Ringvoll Normann, Tove Lekva, Ivars Silamikelis

Eur J Endocrinol· March 2018

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