Publications by authors named "Iwen Fu"

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Peptide Sequence and Cross-Link Structure Influence Translesion Synthesis Polymerase Bypass of 5-Formylcytosine-Mediated DNA-Peptide Cross-Links.
Qi Zhang, Iwen Fu, Suse Broyde, Natalia Y Tretyakova

Chem Res Toxicol· October 2025

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Variable Inhibition of DNA Unwinding Rates Catalyzed by the SARS-CoV-2 Helicase Nsp13 by Structurally Distinct Single DNA Lesions.
Ana H Sales, Iwen Fu, Alexander Durandin, Sam Ciervo, Tania J Lupoli

Int J Mol Sci· July 2024

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Differing structures and dynamics of two photolesions portray verification differences by the human XPD helicase.
Iwen Fu, Nicholas E Geacintov, Suse Broyde

Nucleic Acids Res· December 2023

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Mechanism of lesion verification by the human XPD helicase in nucleotide excision repair.
Iwen Fu, Hong Mu, Nicholas E Geacintov, Suse Broyde

Nucleic Acids Res· July 2022

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Molecular dynamics simulations reveal how H3K56 acetylation impacts nucleosome structure to promote DNA exposure for lesion sensing.
Iwen Fu, Nicholas E Geacintov, Suse Broyde

DNA Repair (Amst)· November 2021

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Translesion Synthesis Past 5-Formylcytosine-Mediated DNA-Peptide Cross-Links by hPolη Is Dependent on the Local DNA Sequence.
Jenna Thomforde, Iwen Fu, Freddys Rodriguez, Suresh S Pujari, Suse Broyde

Biochemistry· June 2021

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Transcriptional Bypass of DNA-Protein and DNA-Peptide Conjugates by T7 RNA Polymerase.
Shaofei Ji, Jenna Thomforde, Colette Rogers, Iwen Fu, Suse Broyde

ACS Chem Biol· December 2019

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5-Formylcytosine-induced DNA-peptide cross-links reduce transcription efficiency, but do not cause transcription errors in human cells.
Shaofei Ji, Daeyoon Park, Konstantin Kropachev, Marina Kolbanovskiy, Iwen Fu

J Biol Chem· November 2019

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Rotational and translational positions determine the structural and dynamic impact of a single ribonucleotide incorporated in the nucleosome.
Iwen Fu, Duncan J Smith, Suse Broyde

DNA Repair (Amst)· January 2019

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Corrigendum: 5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce mutations in human cells.
Shaofei Ji, Iwen Fu, Spandana Naldiga, Hongzhao Shao, Ashis K Basu

Nucleic Acids Res· October 2018

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5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce mutations in human cells.
Shaofei Ji, Iwen Fu, Spandana Naldiga, Hongzhao Shao, Ashis K Basu

Nucleic Acids Res· July 2018

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Synergistic effects of H3 and H4 nucleosome tails on structure and dynamics of a lesion-containing DNA: Binding of a displaced lesion partner base to the H3 tail for GG-NER recognition.
Yuqin Cai, Iwen Fu, Nicholas E Geacintov, Yingkai Zhang, Suse Broyde

DNA Repair (Amst)· May 2018

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Nucleosome Histone Tail Conformation and Dynamics: Impacts of Lysine Acetylation and a Nearby Minor Groove Benzo[a]pyrene-Derived Lesion.
Iwen Fu, Yuqin Cai, Nicholas E Geacintov, Yingkai Zhang, Suse Broyde

Biochemistry· April 2017

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Bypass of DNA-Protein Cross-links Conjugated to the 7-Deazaguanine Position of DNA by Translesion Synthesis Polymerases.
Susith Wickramaratne, Shaofei Ji, Shivam Mukherjee, Yan Su, Matthew G Pence, Iwen Fu

J Biol Chem· November 2016

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Entrapment of a Histone Tail by a DNA Lesion in a Nucleosome Suggests the Lesion Impacts Epigenetic Marking: A Molecular Dynamics Study.
Iwen Fu, Yuqin Cai, Yingkai Zhang, Nicholas E Geacintov, Suse Broyde

Biochemistry· January 2016

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Dynamic Water-Mediated Hydrogen Bonding in a Collagen Model Peptide.
Iwen Fu, David A Case, Jean Baum

Biochemistry· October 2015

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