Publications by authors named "J Apgar"

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A Tutorial on the Development of a Physiologically Inspired PKRO Model for Monoclonal Antibodies.
Georgi I Kapitanov, David Flowers, Diana H Marcantonio, Timothy R Lezon, Josh F Apgar

CPT Pharmacometrics Syst Pharmacol· December 2025

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Towards a platform quantitative systems pharmacology (QSP) model for preclinical to clinical translation of antibody drug conjugates (ADCs).
Bruna Scheuher, Khem Raj Ghusinga, Kimiko McGirr, Maksymilian Nowak, Sheetal Panday, Joshua Apgar

J Pharmacokinet Pharmacodyn· October 2024

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Comparison of dose selection based on target engagement versus inhibition of receptor-ligand interaction for checkpoint inhibitors.
Sarah A Head, Carter Johnson, Saheli Sarkar, Andrew Matteson, Diana H Marcantonio, Joshua F Apgar

CPT Pharmacometrics Syst Pharmacol· June 2024

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Mechanistic PK/PD modeling to address early-stage biotherapeutic dosing feasibility questions.
Joshuaine Grant, Fei Hua, Joshua F Apgar, John M Burke, Diana H Marcantonio

MAbs· March 2023

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Low-data interpretable deep learning prediction of antibody viscosity using a biophysically meaningful representation.
Brajesh K Rai, James R Apgar, Eric M Bennett

Sci Rep· February 2023

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