Publications by authors named "Sarah A Head"

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In silico RNA isoform screening to identify potential cancer driver exons with therapeutic applications.
Miquel Anglada-Girotto, Ludovica Ciampi, Sophie Bonnal, Sarah A Head, Samuel Miravet-Verde

Nat Commun· August 2024

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Insights into the structure-activity relationship of the anticancer compound ZJ-101: A role played by the amide moiety.
Haibo Qiu, Shan Qian, Sarah A Head, Phillip R Sanchez, Jun O Liu

Bioorg Med Chem Lett· June 2024

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Comparison of dose selection based on target engagement versus inhibition of receptor-ligand interaction for checkpoint inhibitors.
Sarah A Head, Carter Johnson, Saheli Sarkar, Andrew Matteson, Diana H Marcantonio

CPT Pharmacometrics Syst Pharmacol· June 2024

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Synthesis and biological evaluation of biotinylated ZJ-101.
Shan Qian, Sarah A Head, Phillip R Sanchez, Jun O Liu, Zhendong Jin

Bioorg Med Chem Lett· July 2023

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Modulation of the Endomembrane System by the Anticancer Natural Product Superstolide/ZJ-101.
Phillip R Sanchez, Sarah A Head, Shan Qian, Haibo Qiu, Avishek Roy

Int J Mol Sci· May 2023

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robustica: customizable robust independent component analysis.
Miquel Anglada-Girotto, Samuel Miravet-Verde, Luis Serrano, Sarah A Head

BMC Bioinformatics· December 2022

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Specialization of the photoreceptor transcriptome by -dependent microexons is required for outer segment maintenance and vision.
Ludovica Ciampi, Federica Mantica, Laura López-Blanch, Jon Permanyer, Cristina Rodriguez-Marín, Sarah A Head

Proc Natl Acad Sci U S A· July 2022

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Silencing of SRRM4 suppresses microexon inclusion and promotes tumor growth across cancers.
Sarah A Head, Xavier Hernandez-Alias, Jae-Seong Yang, Ludovica Ciampi, Violeta Beltran-Sastre

PLoS Biol· February 2021

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ProteinFishing: a protein complex generator within the ModelX toolsuite.
Damiano Cianferoni, Leandro G Radusky, Sarah A Head, Luis Serrano, Javier Delgado

Bioinformatics· August 2020

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Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors.
Yingjun Li, Kalyan Kumar Pasunooti, Hanjing Peng, Ruo-Jing Li, Wei Q Shi, Sarah A Head

ACS Med Chem Lett· June 2020

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Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking.
Junfang Lyu, Eun Ju Yang, Sarah A Head, Nana Ai, Baoyuan Zhang

Int J Biol Sci· August 2019

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Novel Tetrazole-Containing Analogues of Itraconazole as Potent Antiangiogenic Agents with Reduced Cytochrome P450 3A4 Inhibition.
Yingjun Li, Kalyan Kumar Pasunooti, Ruo-Jing Li, Wukun Liu, Sarah A Head

J Med Chem· December 2018

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Clofoctol and sorafenib inhibit prostate cancer growth via synergistic induction of endoplasmic reticulum stress and UPR pathways.
Lixia Fan, Zhenglei He, Sarah A Head, Yinghui Zhou, Ting Lu

Cancer Manag Res· October 2018

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Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP).
Lisa Bauer, Salvatore Ferla, Sarah A Head, Shridhar Bhat, Kalyan K Pasunooti

Antiviral Res· August 2018

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Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth.
Junfang Lyu, Eun Ju Yang, Sarah A Head, Nana Ai, Baoyuan Zhang

Cancer Lett· November 2017

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Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis.
Sarah A Head, Wei Q Shi, Eun Ju Yang, Benjamin A Nacev, Sam Y Hong

ACS Chem Biol· January 2017

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Insights into the structure-activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A role played by the lactone moiety.
Haibo Qiu, Shan Qian, Sarah A Head, Jun O Liu, Zhendong Jin

Bioorg Med Chem Lett· October 2016

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Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation.
Qing-Li He, Il Minn, Qiaoling Wang, Peng Xu, Sarah A Head

Angew Chem Int Ed Engl· September 2016

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Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling.
Sarah A Head, Jun O Liu

J Vis Exp· September 2016

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Insights into the structure-activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A critical role played by the conjugated trienyl lactone moiety.
Shan Qian, Aashay K Shah, Sarah A Head, Jun O Liu, Zhendong Jin

Bioorg Med Chem Lett· August 2016

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Divergence of Antiangiogenic Activity and Hepatotoxicity of Different Stereoisomers of Itraconazole.
Joong Sup Shim, Ruo-Jing Li, Namandje N Bumpus, Sarah A Head, Kalyan Kumar Pasunooti

Clin Cancer Res· June 2016

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Insights into the structure-activity relationship of the anticancer compound ZJ-101: A critical role played by the cyclohexene ring.
Aashay K Shah, Shan Qian, Dawei Zhang, Sarah A Head, Jun O Liu

Bioorg Med Chem Lett· June 2016

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Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells.
Sarah A Head, Wei Shi, Liang Zhao, Kirill Gorshkov, Kalyan Pasunooti

Proc Natl Acad Sci U S A· December 2015

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Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonism.
Joong Sup Shim, Ruo-Jing Li, Junfang Lv, Sarah A Head, Eun Ju Yang

Cancer Lett· June 2015

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Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein.
Jeroen R P M Strating, Lonneke van der Linden, Lucian Albulescu, Joëlle Bigay, Minetaro Arita, Sarah A Head

Cell Rep· February 2015

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