Publications by authors named "JC Portais"

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Overflow metabolism in bacterial, yeast, and mammalian cells: different names, same game.
Thomas Gosselin-Monplaisir, Brice Enjalbert, Sandrine Uttenweiler-Joseph, Jean-Charles Portais, Stéphanie Heux

Mol Syst Biol· November 2025

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Brown adipose tissue activity impacts systemic lactate clearance in male mice.
Rémi Montané, Yannick Jeanson, Damien Lagarde, Spiro Khoury, Léana Porcher-Bibes, Jean-Charles Portais

J Physiol· November 2025

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The glycosomal ATP-dependent phosphofructokinase of Trypanosoma brucei operates also in the gluconeogenic direction.
Nicolas Plazolles, Hanna Kulyk, Edern Cahoreau, Marc Biran, Marion Wargnies, Jean-Charles Portais

PLoS Biol· May 2025

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PhysioFit: a software to quantify cell growth parameters and extracellular fluxes.
Loïc Le Grégam, Yann Guitton, Floriant Bellvert, Stéphanie Heux, Fabien Jourdan, Jean-Charles Portais

Bioinformatics· August 2024

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Cytidine deaminase-dependent mitochondrial biogenesis as a potential vulnerability in pancreatic cancer cells.
Audrey Frances, Audrey Lumeau, Nicolas Bery, Marion Gayral, Lucille Stuani, Jean-Charles Portais

Commun Biol· August 2024

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Weak neuronal glycolysis sustains cognition and organismal fitness.
Daniel Jimenez-Blasco, Jesús Agulla, Rebeca Lapresa, Marina Garcia-Macia, Veronica Bobo-Jimenez, Jean-Charles Portais

Nat Metab· July 2024

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Integrative Multimodal Metabolomics to Early Predict Cognitive Decline Among Amyloid Positive Community-Dwelling Older Adults.
Marie Tremblay-Franco, Cécile Canlet, Audrey Carriere, Jean Nakhle, Anne Galinier, Jean-Charles Portais

J Gerontol A Biol Sci Med Sci· May 2024

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Lipidomic analysis of differently prepared platelet concentrates in additive solution during storage.
Anne-Claire Duchez, Sébastien Fauteux-Daniel, Theo Ebermeyer, Marco Heestermans, Charles-Antoine Arthaud, Jean-Charles Portais

Blood Transfus· September 2023

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An optimization method for untargeted MS-based isotopic tracing investigations of metabolism.
Noémie Butin, Cécilia Bergès, Jean-Charles Portais, Floriant Bellvert

Metabolomics· June 2022

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GC/MS-based C metabolic flux analysis resolves the parallel and cyclic photomixotrophic metabolism of Synechocystis sp. PCC 6803 and selected deletion mutants including the Entner-Doudoroff and phosphoketolase pathways.
Dennis Schulze, Michael Kohlstedt, Judith Becker, Edern Cahoreau, Lindsay Peyriga, Jean-Charles Portais

Microb Cell Fact· April 2022

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MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle.
Thibaut Molinié, Elodie Cougouilles, Claudine David, Edern Cahoreau, Jean-Charles Portais

Biochim Biophys Acta Bioenerg· March 2022

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The metabolic signaling of the nucleoredoxin-like 2 gene supports brain function.
Céline Jaillard, Farah Ouechtati, Emmanuelle Clérin, Géraldine Millet-Puel, Mariangela Corsi, Jean-Charles Portais

Redox Biol· December 2021

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Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis.
Maria I Matias, Carmen S Yong, Amir Foroushani, Chloe Goldsmith, Cédric Mongellaz, Jean-Charles Portais

Cell Rep· November 2021

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Lactate fluxes mediated by the monocarboxylate transporter-1 are key determinants of the metabolic activity of beige adipocytes.
Damien Lagarde, Yannick Jeanson, Corinne Barreau, Cedric Moro, Lindsay Peyriga, Jean-Charles Portais

J Biol Chem· August 2021

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Glycerol suppresses glucose consumption in trypanosomes through metabolic contest.
Stefan Allmann, Marion Wargnies, Nicolas Plazolles, Edern Cahoreau, Marc Biran, Jean-Charles Portais

PLoS Biol· August 2021

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IsoSolve: An Integrative Framework to Improve Isotopic Coverage and Consolidate Isotopic Measurements by Mass Spectrometry and/or Nuclear Magnetic Resonance.
Pierre Millard, Serguei Sokol, Michael Kohlstedt, Christoph Wittmann, Fabien Létisse, Jean-Charles Portais

Anal Chem· July 2021

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The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place.
Oriana Villafraz, Hélène Baudouin, Muriel Mazet, Hanna Kulyk, Jean-William Dupuy, Jean-Charles Portais

mBio· June 2021

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Lactate Fluxes and Plasticity of Adipose Tissues: A Redox Perspective.
Damien Lagarde, Yannick Jeanson, Jean-Charles Portais, Anne Galinier, Isabelle Ader

Front Physiol· June 2021

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Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia.
Lucille Stuani, Marie Sabatier, Estelle Saland, Guillaume Cognet, Nathalie Poupin, Jean-Charles Portais

J Exp Med· May 2021

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Exploring the Glucose Fluxotype of the y-ome Using High-Resolution Fluxomics.
Cécilia Bergès, Edern Cahoreau, Pierre Millard, Brice Enjalbert, Mickael Dinclaux, Jean-Charles Portais

Metabolites· April 2021

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Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline.
Oriana Villafraz, Marc Biran, Erika Pineda, Nicolas Plazolles, Edern Cahoreau, Jean-Charles Portais

PLoS Pathog· March 2021

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Control and regulation of acetate overflow in .
Pierre Millard, Brice Enjalbert, Sandrine Uttenweiler-Joseph, Jean-Charles Portais, Fabien Létisse

Elife· March 2021

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Extracellular ATP and CD39 Activate cAMP-Mediated Mitochondrial Stress Response to Promote Cytarabine Resistance in Acute Myeloid Leukemia.
Nesrine Aroua, Emeline Boet, Margherita Ghisi, Marie-Laure Nicolau-Travers, Estelle Saland, Jean-Charles Portais

Cancer Discov· October 2020

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Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma.
Madi Y Cissé, Samuel Pyrdziak, Nelly Firmin, Laurie Gayte, Maud Heuillet, Jean-Charles Portais

Sci Transl Med· June 2020

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ScalaFlux: A scalable approach to quantify fluxes in metabolic subnetworks.
Pierre Millard, Uwe Schmitt, Patrick Kiefer, Julia A Vorholt, Stéphanie Heux, Jean-Charles Portais

PLoS Comput Biol· April 2020

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