Publications by authors named "JM Spaeth"

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CHD3 and CHD4 coordinate gene expression programs to maintain β-cell function and identity .
Sukrati Kanojia, Avinil Das Sharma, Rajani M George, Abigail G Taylor, Wenting Wu, Jason M Spaeth

Res Sq· November 2025

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The SWI/SNF chromatin remodelling complex regulates pancreatic endocrine cell expansion and differentiation in mice in vivo.
Rebecca K Davidson, Wenting Wu, Sukrati Kanojia, Rajani M George, Kayla Huter, Jason M Spaeth

Diabetologia· October 2024

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Dynamic regulation of pancreatic β cell function and gene expression by the SND1 coregulator .
Sukrati Kanojia, Rebecca K Davidson, Jason M Conley, Jerry Xu, Meredith Osmulski, Jason M Spaeth

Islets· December 2023

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The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for β-Cell Function In Vivo.
Rebecca K Davidson, Sukrati Kanojia, Wenting Wu, Tatsuyoshi Kono, Jerry Xu, Jason M Spaeth

Diabetes· June 2023

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The Yin and Yang of Modulating β-Cell DNA Damage Response and Functional Mass.
Jason M Spaeth, Sangeeta Dhawan

Diabetes· August 2022

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The Chd4 subunit of the NuRD complex regulates Pdx1-controlled genes involved in β-cell function.
Rebecca K Davidson, Staci A Weaver, Nolan Casey, Sukrati Kanojia, Elise Hogarth, Jason M Spaeth

J Mol Endocrinol· June 2022

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The Contribution of Transcriptional Coregulators in the Maintenance of β-cell Function and Identity.
Rebecca K Davidson, Sukrati Kanojia, Jason M Spaeth

Endocrinology· February 2021

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The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function.
Jason M Spaeth, Jin-Hua Liu, Daniel Peters, Min Guo, Anna B Osipovich

Diabetes· September 2019

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HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes.
Mark A Russell, Sambra D Redick, David M Blodgett, Sarah J Richardson, Pia Leete, Jason M Spaeth

Diabetes· May 2019

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B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib.
Christopher S Wilson, Jason M Spaeth, Jay Karp, Blair T Stocks, Emilee M Hoopes

JCI Insight· April 2019

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Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.
Min Ju Park, Hailian Shen, Jason M Spaeth, Jaana H Tolvanen, Courtney Failor

J Biol Chem· March 2018

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Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning.
Jason M Spaeth, Manisha Gupte, Mark Perelis, Yu-Ping Yang, Holly Cyphert

Diabetes· November 2017

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Impact of Pdx1-associated chromatin modifiers on islet β-cells.
J M Spaeth, E M Walker, R Stein

Diabetes Obes Metab· September 2016

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The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice.
Jason M Spaeth, Chad S Hunter, Lauren Bonatakis, Min Guo, Catherine A French

Diabetologia· August 2015

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Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.
Mikko Turunen, Jason M Spaeth, Salla Keskitalo, Min Ju Park, Teemu Kivioja

Cell Rep· May 2014

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MED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signaling.
Haiying Zhou, Jason M Spaeth, Nam Hee Kim, Xuan Xu, Michael J Friez

Proc Natl Acad Sci U S A· November 2012

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Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet.
Philippe Krebs, Weiwei Fan, Yen-Hui Chen, Kimimasa Tobita, Michael R Downes, Jason M Spaeth

Proc Natl Acad Sci U S A· December 2011

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Mediator and human disease.
Jason M Spaeth, Nam Hee Kim, Thomas G Boyer

Semin Cell Dev Biol· September 2011

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Measurement of Cu(II) copper defect dipoles in ferroelectric PbTiO3 using electron-nuclear double resonance.
R R Garipov, J-M Spaeth, D J Keeble

Phys Rev Lett· December 2008

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High-field optically detected EPR and ENDOR of semiconductor defects using W-band microwave Fabry-Pérot resonators.
J-M Spaeth, I Tkach, S Greulich-Weber, H Overhof

Magn Reson Chem· November 2005

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Ni2+ ions in RbCdF3: An EPR study in the cubic and tetragonal phases.
PJ Alonso, R Alcalá, JM Spaeth

Phys Rev B Condens Matter· June 1990

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Arsenic antisite defects in AlxGa1-xAs observed by luminescence-detected electron-spin resonance.
M Fockele, BK Meyer, JM Spaeth, M Heuken, K Heime

Phys Rev B Condens Matter· July 1989

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Unification of the properties of the EL2 defect in GaAs.
M Hoinkis, ER Weber, W Walukiewicz, J Lagowski, M Matsui, JM Spaeth

Phys Rev B Condens Matter· March 1989

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Structure of a (RhCl6)4- defect in AgCl.
MT Olm, JR Niklas, JM Spaeth, MC Symons

Phys Rev B Condens Matter· September 1988

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Theory of indirect hyperfine interactions of oxygen-aluminum defects in ionic crystals.
FJ Adrian, AN Jette, JM Spaeth

Phys Rev B Condens Matter· March 1985

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