Publications by authors named "JOHN RANDELL"

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The Human Cell Atlas from a cell census to a unified foundation model.
Jennifer E Rood, Samantha Wynne, Lucia Robson, Anna Hupalowska, John Randell

Nature· January 2025

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Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7.
John C W Randell, Andy Fan, Clara Chan, Laura I Francis, Ryan C Heller

Mol Cell· November 2010

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Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation.
Laura I Francis, John C W Randell, Thomas J Takara, Lilen Uchima, Stephen P Bell

Genes Dev· March 2009

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Herpes simplex virus mutants with multiple substitutions affecting DNA binding of UL42 are impaired for viral replication and DNA synthesis.
Changying Jiang, Ying T Hwang, Guangliang Wang, John C W Randell, Donald M Coen

J Virol· November 2007

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Mutations that decrease DNA binding of the processivity factor of the herpes simplex virus DNA polymerase reduce viral yield, alter the kinetics of viral DNA replication, and decrease the fidelity of DNA replication.
Changying Jiang, Ying T Hwang, John C W Randell, Donald M Coen, Charles B C Hwang

J Virol· April 2007

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Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase.
John C W Randell, Jayson L Bowers, Heather K Rodríguez, Stephen P Bell

Mol Cell· January 2006

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Effects of substitutions of arginine residues on the basic surface of herpes simplex virus UL42 support a role for DNA binding in processive DNA synthesis.
John C W Randell, Gloria Komazin, Changying Jiang, Charles B C Hwang, Donald M Coen

J Virol· September 2005

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ATP hydrolysis by ORC catalyzes reiterative Mcm2-7 assembly at a defined origin of replication.
Jayson L Bowers, John C W Randell, Shuyan Chen, Stephen P Bell

Mol Cell· December 2004

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The herpes simplex virus processivity factor, UL42, binds DNA as a monomer.
John C W Randell, Donald M Coen

J Mol Biol· January 2004

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COMBINING THE ANTIDEPRESSANT DRUGS.
JOHN RANDELL

Br Med J· February 1965

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