Publications by authors named "JR Hughes"

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Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA.
Lauren Murphy, Jeanne Inchauspé, Giampiero Valenzano, Pamela Holland, Nikolaos Sousos, Jim R Hughes

Science· August 2025

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Radiobiological characterisation of a 28 MeV proton beam delivered by the MC-40 cyclotron.
Maria Rita Fabbrizi, Jonathan R Hughes, Leah D Punshon, Laura Hawkins, Vasily Sorokin

Cell Death Discov· July 2025

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Live Attenuated Vaccine Administration in Children Treated With Methotrexate or Dupilumab.
Julia R Hughes, Sino Mehrmal, Sana Habib, Howard L Williams, Elaine C Siegfried

Pediatr Dermatol· April 2025

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Active regulatory elements recruit cohesin to establish cell specific chromatin domains.
Emily Georgiades, Caroline Harrold, Nigel Roberts, Mira Kassouf, Simone G Riva, Jim R Hughes

Sci Rep· April 2025

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Author Correction: The α-globin super-enhancer acts in an orientation-dependent manner.
Mira T Kassouf, Helena S Francis, Matthew Gosden, Maria C Suciu, Damien J Downes, Jim R Hughes

Nat Commun· March 2025

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Ancient genomic linkage of α-globin and Nprl3 couples metabolism with erythropoiesis.
Alexandra E Preston, Joe N Frost, Megan R Teh, Mohsin Badat, Andrew E Armitage, Jim R Hughes

Nat Commun· March 2025

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Does coenzyme Q10 improve semen quality and circulating testosterone level? a systematic review and meta-analysis of randomized controlled trials.
Tunmise M Akhigbe, Fabrael B Fidelis, Adebayo O Adekunle, Victory J Ashonibare, Bolaji A Akorede, Jennifer R Hughes

Front Pharmacol· January 2025

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The α-globin super-enhancer acts in an orientation-dependent manner.
Mira T Kassouf, Helena S Francis, Matthew Gosden, Maria C Suciu, Damien J Downes, Jim R Hughes

Nat Commun· January 2025

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scATAC-seq generates more accurate and complete regulatory maps than bulk ATAC-seq.
E Ravza Gur, Jim R Hughes

Sci Rep· January 2025

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HDAC Inhibitors Can Enhance Radiosensitivity of Head and Neck Cancer Cells Through Suppressing DNA Repair.
Jennifer Antrobus, Bethany Mackinnon, Emma Melia, Jonathan R Hughes, Jason L Parsons

Cancers (Basel)· December 2024

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Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia.
Sunniyat Rahman, Gianna Bloye, Nadine Farah, Jonas Demeulemeester, Joana R Costa, Jim R Hughes

Blood· November 2024

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Chromatin remodeller Chd7 is developmentally regulated in the neural crest by tissue-specific transcription factors.
Ruth M Williams, Guneş Taylor, Irving T C Ling, Ivan Candido-Ferreira, Daniel M Fountain, Jim R Hughes

PLoS Biol· October 2024

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Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes.
Guanjue Xiang, Xi He, Belinda M Giardine, Kathryn J Isaac, Dylan J Taylor, Jim R Hughes

Genome Res· August 2024

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Single-cell technologies meet Hi-C.
Jim R Hughes, James O J Davies

Nat Genet· August 2024

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Inhibition of key DNA double strand break repair protein kinases enhances radiosensitivity of head and neck cancer cells to X-ray and proton irradiation.
Maria Rita Fabbrizi, Thomas J Doggett, Jonathan R Hughes, Emma Melia, Elizabeth R Dufficy

Cell Death Discov· June 2024

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Autophagy is the main driver of radioresistance of HNSCC cells in mild hypoxia.
Rhianna M Hill, Chun Li, Jonathan R Hughes, Sonia Rocha, Gabrielle J Grundy

J Cell Mol Med· June 2024

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Patient satisfaction and outcomes within a free dermatology clinic implemented at an academic medical center.
Julia R Hughes, Brooke McCollum, Rylee Moody, Isra N Taha, Saniya Shaikh

Dermatol Online J· June 2024

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Computed tomographic features of canine intracranial and jugular foraminal masses involving the combined glossopharyngeal, vagus, and accessory nerve roots.
Begoña Lluesma, Nathaniel T Whitley, Jonathan R Hughes

Vet Radiol Ultrasound· May 2024

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Does pyrethroid exposure lower human semen quality? a systematic review and meta-analysis.
Roland Eghoghosoa Akhigbe, Precious Adeoye Oyedokun, Tunmise Maryanne Akhigbe, Suliat Adenike, Ayoola Abimbola Oladipo, Jennifer Rose Hughes

Front Toxicol· May 2024

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A novel abuse liability assessment of e-cigarettes in young adults ii: Reinforcement enhancement and follow-up assessment.
Ari P Kirshenbaum, Virginia Kelsey, Mia Cooper, Anthony E Richardson, John R Hughes

Exp Clin Psychopharmacol· April 2024

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Targeting OGG1 and PARG radiosensitises head and neck cancer cells to high-LET protons through complex DNA damage persistence.
Maria Rita Fabbrizi, Catherine M Nickson, Jonathan R Hughes, Emily A Robinson, Karthik Vaidya

Cell Death Dis· February 2024

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Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases.
Alistair T Pagnamenta, Carme Camps, Edoardo Giacopuzzi, John M Taylor, Mona Hashim, Jim R Hughes

Genome Med· November 2023

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Ancient genomic linkage couples metabolism with erythroid development.
Alexandra E Preston, Joe N Frost, Mohsin Badat, Megan Teh, Andrew E Armitage, Jim R Hughes

bioRxiv· September 2023

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CATCH-UP: A High-Throughput Upstream-Pipeline for Bulk ATAC-Seq and ChIP-Seq Data.
Simone G Riva, Emily Georgiades, E Ravza Gur, Matthew Baxter, Jim R Hughes

J Vis Exp· September 2023

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Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells.
Jason M Torres, Han Sun, Vibe Nylander, Damien J Downes, Martijn van de Bunt, Jim R Hughes

Wellcome Open Res· August 2023

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