Publications by authors named "Jaap Neels"

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CSF1R regulates monocyte subset differentiation and intracellular metabolism.
Alexandre Gallerand, Johanna Merlin, Zakariya Caillot, Chloé Delaby, Elisa Bord, Jaap G Neels

bioRxiv· July 2025

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An exploratory human study investigating the influence of type 2 diabetes on macrophage phenotype after myocardial infarction.
Claudine Moratal, Joseph Murdaca, Coralie Cruzel, Amina Zamiti-Smondel, Nathan Heme, Jaap G Neels

Int J Cardiol Heart Vasc· December 2023

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Trem2 promotes foamy macrophage lipid uptake and survival in atherosclerosis.
Michael T Patterson, Maria M Firulyova, Yingzheng Xu, Hannah Hillman, Courtney Bishop, Jaap G Neels

Nat Cardiovasc Res· November 2023

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Macrophage death in atherosclerosis: potential role in calcification.
Jaap G Neels, Claire Gollentz, Giulia Chinetti

Front Immunol· July 2023

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Atherosclerosis Calcification: Focus on Lipoproteins.
Jaap G Neels, Georges Leftheriotis, Giulia Chinetti

Metabolites· March 2023

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Identification of a circulating immunological signature predictive of response to immune checkpoint inhibitors in patients with advanced non-small cell lung cancer.
Wassila Khatir, Olivier Humbert, Jonathan Benzaquen, Christophe Bontoux, Jaap Neels

Clin Transl Med· August 2022

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Diabetes-Induced Changes in Macrophage Biology Might Lead to Reduced Risk for Abdominal Aortic Aneurysm Development.
Giulia Chinetti, Joseph Carboni, Joseph Murdaca, Claudine Moratal, Brigitte Sibille, Jaap G Neels

Metabolites· January 2022

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Gene Doping with Peroxisome-Proliferator-Activated Receptor Beta/Delta Agonists Alters Immunity but Exercise Training Mitigates the Detection of Effects in Blood Samples.
Brigitte Sibille, Isabelle Mothe-Satney, Gwenaëlle Le Menn, Doriane Lepouse, Sébastien Le Garf, Jaap G Neels

Int J Mol Sci· October 2021

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Regulation of Monocytes/Macrophages by the Renin-Angiotensin System in Diabetic Nephropathy: State of the Art and Results of a Pilot Study.
Claudine Moratal, Audrey Laurain, Mourad Naïmi, Thibault Florin, Vincent Esnault, Jaap G Neels

Int J Mol Sci· June 2021

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Roles of Nuclear Receptors in Vascular Calcification.
Giulia Chinetti, Jaap G Neels

Int J Mol Sci· June 2021

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Alpha-lipoic acid supplementation increases the efficacy of exercise- and diet-induced obesity treatment and induces immunometabolic changes in female mice and women.
Sébastien Le Garf, Brigitte Sibille, Isabelle Mothe-Satney, Cyril Eininger, Philippe Fauque, Jaap G Neels

FASEB J· April 2021

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Invalidation of the Transcriptional Modulator of Lipid Metabolism PPARβ/δ in T Cells Prevents Age-Related Alteration of Body Composition and Loss of Endurance Capacity.
Anne-Sophie Rousseau, Joseph Murdaca, Gwenaëlle Le Menn, Brigitte Sibille, Walter Wahli, Jaap G Neels

Front Physiol· March 2021

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Nuclear receptors in abdominal aortic aneurysms.
Jaap G Neels, Réda Hassen-Khodja, Giulia Chinetti

Atherosclerosis· March 2020

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Complementary Immunometabolic Effects of Exercise and PPARβ/δ Agonist in the Context of Diet-Induced Weight Loss in Obese Female Mice.
Sébastien Le Garf, Joseph Murdaca, Isabelle Mothe-Satney, Brigitte Sibille, Gwenaëlle Le Menn, Jaap G Neels

Int J Mol Sci· October 2019

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GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism.
Laura Mondragón, Rana Mhaidly, Gian Marco De Donatis, Marie Tosolini, Pascal Dao, Jaap G Neels

Cancer Cell· September 2019

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Decrease in αβ/γδ T-cell ratio is accompanied by a reduction in high-fat diet-induced weight gain, insulin resistance, and inflammation.
Gwenaëlle Le Menn, Brigitte Sibille, Joseph Murdaca, Anne-Sophie Rousseau, Raphaëlle Squillace, Jaap G Neels

FASEB J· February 2019

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Investigation of Plasma Inflammatory Profile in Diabetic Patients With Abdominal Aortic Aneurysm: A Pilot Study.
Fabien Lareyre, Claudine Moratal, Julien Chikande, Elixène Jean-Baptiste, Réda Hassen-Khodja, Jaap Neels

Vasc Endovascular Surg· November 2018

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Regulation of Immune Cell Function by PPARs and the Connection with Metabolic and Neurodegenerative Diseases.
Gwenaëlle Le Menn, Jaap G Neels

Int J Mol Sci· May 2018

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Peroxisome Proliferator Activated Receptor Beta (PPARβ) activity increases the immune response and shortens the early phases of skeletal muscle regeneration.
Isabelle Mothe-Satney, Jessica Piquet, Joseph Murdaca, Brigitte Sibille, Paul A Grimaldi, Jaap G Neels

Biochimie· May 2017

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A role for Peroxisome Proliferator-Activated Receptor Beta in T cell development.
Isabelle Mothe-Satney, Joseph Murdaca, Brigitte Sibille, Anne-Sophie Rousseau, Raphaëlle Squillace, Jaap G Neels

Sci Rep· September 2016

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α-Lipoic acid up-regulates expression of peroxisome proliferator-activated receptor β in skeletal muscle: involvement of the JNK signaling pathway.
Anne-Sophie Rousseau, Brigitte Sibille, Joseph Murdaca, Isabelle Mothe-Satney, Paul A Grimaldi, Jaap G Neels

FASEB J· March 2016

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Physiological functions of peroxisome proliferator-activated receptor β.
Jaap G Neels, Paul A Grimaldi

Physiol Rev· July 2014

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A role for 5-lipoxygenase products in obesity-associated inflammation and insulin resistance.
Jaap G Neels

Adipocyte· October 2013

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Adipocytes secrete leukotrienes: contribution to obesity-associated inflammation and insulin resistance in mice.
Isabelle Mothe-Satney, Chantal Filloux, Hind Amghar, Catherine Pons, Virginie Bourlier, Jaap G Neels

Diabetes· September 2012

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Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice.
Justin Chapman, Philip D Miles, Jachelle M Ofrecio, Jaap G Neels, Joseph G Yu

PLoS One· November 2010

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