Publications by authors named "Jaap Rip"

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In vitro and in vivo delivery of mRNA to joint cells using polymeric nanoparticles.
Adriano P Pontes, Jaqueline Lourdes Rios, Mattie Rijker, Kelly Warmink, Shreya Gudi, Jaap Rip

Acta Biomater· August 2025

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Improved tendon repair with optimized chemically modified mRNAs: Combined delivery of Pdgf-BB and IL-1Ra using injectable nanoparticles.
Bettina Faustini, Thomas Lettner, Andrea Wagner, Herbert Tempfer, Nevra Pelin Cesur, Jaap Rip

Acta Biomater· March 2025

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Polymeric nanoparticle-based mRNA vaccine is protective against influenza virus infection in ferrets.
Gijs Hardenberg, Chantal Brouwer, Rachelle van Gemerden, Nicola J Jones, Anthony C Marriott, Jaap Rip

Mol Ther Nucleic Acids· March 2024

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Polymeric Nanoparticles Enable mRNA Transfection and Its Translation in Intervertebral Disc and Human Joint Cells, Except for M1 Macrophages.
Katrin Agnes Muenzebrock, Fiona Y W Ho, Adriano P Pontes, Carla Jorquera-Cordero, Lizette Utomo, Jaap Rip

Pharmaceutics· March 2024

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A poly(amidoamine)-based polymeric nanoparticle platform for efficient in vivo delivery of mRNA.
Adriano P Pontes, Steffen van der Wal, Karin Roelofs, Anne Grobbink, Laura B Creemers, Jaap Rip

Biomater Adv· January 2024

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Cell uptake and intracellular trafficking of bioreducible poly(amidoamine) nanoparticles for efficient mRNA translation in chondrocytes.
Adriano P Pontes, Steffen van der Wal, Saketh R Ranamalla, Karin Roelofs, Ioan Tomuta, Jaap Rip

Front Bioeng Biotechnol· November 2023

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Polymeric Nanoparticles for Drug Delivery in Osteoarthritis.
Adriano P Pontes, Tim J M Welting, Jaap Rip, Laura B Creemers

Pharmaceutics· November 2022

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In Vitro Evaluation of a Nanoparticle-Based mRNA Delivery System for Cells in the Joint.
Lisa Sturm, Bettina Schwemberger, Ursula Menzel, Sonja Häckel, Christoph E Albers, Jaap Rip

Biomedicines· July 2021

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In Vivo Quantitative Understanding of PEGylated Liposome's Influence on Brain Delivery of Diphenhydramine.
Yang Hu, Pieter J Gaillard, Jaap Rip, Elizabeth C M de Lange, Margareta Hammarlund-Udenaes

Mol Pharm· December 2018

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The Impact of Liposomal Formulations on the Release and Brain Delivery of Methotrexate: An In Vivo Microdialysis Study.
Yang Hu, Jaap Rip, Pieter J Gaillard, Elizabeth C M de Lange, Margareta Hammarlund-Udenaes

J Pharm Sci· September 2017

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Liposome technologies and drug delivery to the CNS.
Jaap Rip

Drug Discov Today Technol· June 2016

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Glutathione conjugation dose-dependently increases brain-specific liposomal drug delivery in vitro and in vivo.
David Maussang, Jaap Rip, Joan van Kregten, Angelique van den Heuvel, Susanne van der Pol

Drug Discov Today Technol· June 2016

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In vivo Functional Evaluation of Increased Brain Delivery of the Opioid Peptide DAMGO by Glutathione-PEGylated Liposomes.
Annika Lindqvist, Jaap Rip, Joan van Kregten, Pieter J Gaillard, Margareta Hammarlund-Udenaes

Pharm Res· January 2016

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Enhanced glutathione PEGylated liposomal brain delivery of an anti-amyloid single domain antibody fragment in a mouse model for Alzheimer's disease.
Maarten Rotman, Mick M Welling, Anton Bunschoten, Maaike E de Backer, Jaap Rip

J Control Release· April 2015

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Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood-brain barrier in rats.
Jaap Rip, Linda Chen, Robin Hartman, Angelique van den Heuvel, Arie Reijerkerk

J Drug Target· June 2014

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Systemic treatment with glutathione PEGylated liposomal methylprednisolone (2B3-201) improves therapeutic efficacy in a model of ocular inflammation.
Arie Reijerkerk, Chantal C M Appeldoorn, Jaap Rip, Marco de Boer, Pieter J Gaillard

Invest Ophthalmol Vis Sci· April 2014

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Enhanced brain delivery of the opioid peptide DAMGO in glutathione pegylated liposomes: a microdialysis study.
Annika Lindqvist, Jaap Rip, Pieter J Gaillard, Sven Björkman, Margareta Hammarlund-Udenaes

Mol Pharm· May 2013

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Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation.
Pieter J Gaillard, Chantal C M Appeldoorn, Jaap Rip, Rick Dorland, Susanne M A van der Pol

J Control Release· December 2012

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Targeted blood-to-brain drug delivery --10 key development criteria.
Pieter J Gaillard, Corine C Visser, Chantal C M Appeldoorn, Jaap Rip

Curr Pharm Biotechnol· September 2012

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Efficient CRM197-mediated drug targeting to monocytes.
Geert J Schenk, P C Joost Haasnoot, Mireille Centlivre, Nicolas Legrand, Jaap Rip

J Control Release· February 2012

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Enhanced apoB48 metabolism in lipoprotein lipase X447 homozygotes.
Melchior C Nierman, Jaap Rip, Jan Albert Kuivenhoven, Naohiko Sakai, John J P Kastelein

Atherosclerosis· October 2007

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Adeno-associated virus LPL(S447X) gene therapy in LDL receptor knockout mice.
Jaap Rip, Jeroen A Sierts, Stefan F C Vaessen, John J P Kastelein, Jaap Twisk

Atherosclerosis· September 2007

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AAV1-LPL(S447X) gene therapy reduces hypertriglyceridemia in apoE2 knock in mice.
Jaap Rip, Ko Willems van Dijk, Jeroen A Sierts, John J P Kastelein, Jaap Twisk

Biochim Biophys Acta· October 2006

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Lipoprotein lipase S447X: a naturally occurring gain-of-function mutation.
Jaap Rip, Melchior C Nierman, Colin J Ross, Jan Wouter Jukema, Michael R Hayden

Arterioscler Thromb Vasc Biol· June 2006

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Correction of feline lipoprotein lipase deficiency with adeno-associated virus serotype 1-mediated gene transfer of the lipoprotein lipase S447X beneficial mutation.
Colin J D Ross, Jaap Twisk, Andrew C Bakker, Fudan Miao, Dennis Verbart, Jaap Rip

Hum Gene Ther· May 2006

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