Publications by authors named "Jacinth Naidoo"

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Bacterial ubiquitin ligase engineered for small molecule and protein target identification.
James S Ye, Abir Majumdar, Brenden C Park, Miles H Black, Ting-Sung Hsieh, Jacinth Naidoo

EMBO J· January 2026

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Bacterial ubiquitin ligase engineered for small molecule and protein target identification.
James S Ye, Abir Majumdar, Brenden C Park, Miles H Black, Ting-Sung Hsieh, Jacinth Naidoo

bioRxiv· March 2025

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A male-derived nonribosomal peptide pheromone controls female schistosome development.
Rui Chen, Jipeng Wang, Irina Gradinaru, Hieu S Vu, Sophie Geboers, Jacinth Naidoo

Cell· April 2022

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Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein.
Kris White, Matthew Esparza, Jue Liang, Prasanna Bhat, Jacinth Naidoo

J Med Chem· August 2021

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Tumor-Activated Benzothiazole Inhibitors of Stearoyl-CoA Desaturase.
Noelle S Williams, Stephen Gonzales, Jacinth Naidoo, Giomar Rivera-Cancel, Sukesh Voruganti

J Med Chem· September 2020

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Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses.
Priya Luthra, Jacinth Naidoo, Colette A Pietzsch, Sampriti De, Sudip Khadka

Antiviral Res· October 2018

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Metabolomics of tomato xylem sap during bacterial wilt reveals Ralstonia solanacearum produces abundant putrescine, a metabolite that accelerates wilt disease.
Tiffany M Lowe-Power, Connor G Hendrich, Edda von Roepenack-Lahaye, Bin Li, Dousheng Wu, Jacinth Naidoo

Environ Microbiol· April 2018

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Spermidine promotes biofilm formation by activating expression of the matrix regulator .
Laura Hobley, Bin Li, Jennifer L Wood, Sok Ho Kim, Jacinth Naidoo

J Biol Chem· July 2017

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Inhibitors of 15-Prostaglandin Dehydrogenase To Potentiate Tissue Repair.
Monika I Antczak, Yongyou Zhang, Changguang Wang, Jennifer Doran, Jacinth Naidoo

J Med Chem· May 2017

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Functional Identification of Putrescine C- and N-Hydroxylases.
Bin Li, Tiffany Lowe-Power, Shin Kurihara, Stephen Gonzales, Jacinth Naidoo

ACS Chem Biol· October 2016

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TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration.
Yongyou Zhang, Amar Desai, Sung Yeun Yang, Ki Beom Bae, Monika I Antczak, Jacinth Naidoo

Science· June 2015

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Protective efficacy of P7C3-S243 in the 6-hydroxydopamine model of Parkinson's disease.
Héctor De Jesús-Cortés, Adam D Miller, Jeremiah K Britt, Anthony J DeMarco, Mayralis De Jesús-Cortés, Jacinth Naidoo

NPJ Parkinsons Dis· May 2015

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Early detection of subclinical visual damage after blast-mediated TBI enables prevention of chronic visual deficit by treatment with P7C3-S243.
Laura M Dutca, Steven F Stasheff, Adam Hedberg-Buenz, Danielle S Rudd, Nikhil Batra, Jacinth Naidoo

Invest Ophthalmol Vis Sci· December 2014

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P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage.
Gelin Wang, Ting Han, Deepak Nijhawan, Pano Theodoropoulos, Jacinth Naidoo

Cell· September 2014

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P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury.
Terry C Yin, Jeremiah K Britt, Héctor De Jesús-Cortés, Yuan Lu, Rachel M Genova, Jacinth Naidoo

Cell Rep· September 2014

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Discovery of a neuroprotective chemical, (S)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(-)-P7C3-S243], with improved druglike properties.
Jacinth Naidoo, Hector De Jesus-Cortes, Paula Huntington, Sandi Estill, Lorraine K Morlock

J Med Chem· May 2014

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Neuroprotective efficacy of a proneurogenic compound after traumatic brain injury.
Meghan O Blaya, Helen M Bramlett, Jacinth Naidoo, Andrew A Pieper, W Dalton Dietrich

J Neurotrauma· March 2014

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Allosteric inhibition of hypoxia inducible factor-2 with small molecules.
Thomas H Scheuermann, Qiming Li, He-Wen Ma, Jason Key, Lei Zhang, Jacinth Naidoo

Nat Chem Biol· April 2013

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Small-molecule activation of the TRAIL receptor DR5 in human cancer cells.
Gelin Wang, Xiaoming Wang, Hong Yu, Shuguang Wei, Noelle Williams, Jacinth Naidoo

Nat Chem Biol· February 2013

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Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor.
Jamie L Rogers, Liela Bayeh, Thomas H Scheuermann, Jamie Longgood, Jason Key, Jacinth Naidoo

J Med Chem· February 2013

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Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis.
Rachel Tesla, Hamilton Parker Wolf, Pin Xu, Jordan Drawbridge, Sandi Jo Estill, Jacinth Naidoo

Proc Natl Acad Sci U S A· October 2012

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Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease.
Héctor De Jesús-Cortés, Pin Xu, Jordan Drawbridge, Sandi Jo Estill, Paula Huntington, Jacinth Naidoo

Proc Natl Acad Sci U S A· October 2012

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Development of proneurogenic, neuroprotective small molecules.
Karen S MacMillan, Jacinth Naidoo, Jue Liang, Lisa Melito, Noelle S Williams

J Am Chem Soc· February 2011

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Discovery of a proneurogenic, neuroprotective chemical.
Andrew A Pieper, Shanhai Xie, Emanuela Capota, Sandi Jo Estill, Jeannie Zhong, Jacinth Naidoo

Cell· July 2010

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