Publications by authors named "Jack Shepherd"

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Invention, innovation, and commercialisation in British biophysics.
Jack Shepherd, Mark C Leake

Biophys Rev· August 2025

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Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers such as DNA.
Jack W Shepherd, Sebastien Guilbaud, Zhaokun Zhou, Jamieson A L Howard, Matthew Burman

Nat Commun· March 2024

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Correlating viscosity and molecular crowding with fluorescent nanobeads and molecular probes: and .
Sarah Lecinski, Jack W Shepherd, Kate Bunting, Lara Dresser, Steven D Quinn

Interface Focus· December 2022

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Crowding-induced morphological changes in synthetic lipid vesicles determined using smFRET.
Steven D Quinn, Lara Dresser, Sarah Graham, Donato Conteduca, Jack Shepherd

Front Bioeng Biotechnol· October 2022

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RecA and RecB: probing complexes of DNA repair proteins with mitomycin C in live with single-molecule sensitivity.
Alex L Payne-Dwyer, Aisha H Syeda, Jack W Shepherd, Lewis Frame, Mark C Leake

J R Soc Interface· August 2022

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The End Restraint Method for Mechanically Perturbing Nucleic Acids In Silico.
Jack W Shepherd, Mark C Leake

Methods Mol Biol· June 2022

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The Effect of Lithium on the Budding Yeast upon Stress Adaptation.
Patrick Reith, Svenja Braam, Niek Welkenhuysen, Sarah Lecinski, Jack Shepherd

Microorganisms· March 2022

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Investigating molecular crowding during cell division and hyperosmotic stress in budding yeast with FRET.
Sarah Lecinski, Jack W Shepherd, Lewis Frame, Imogen Hayton, Chris MacDonald

Curr Top Membr· December 2021

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Molecular crowding in single eukaryotic cells: Using cell environment biosensing and single-molecule optical microscopy to probe dependence on extracellular ionic strength, local glucose conditions, and sensor copy number.
Jack W Shepherd, Sarah Lecinski, Jasmine Wragg, Sviatlana Shashkova, Chris MacDonald

Methods· September 2021

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Elucidating the Role of Topological Constraint on the Structure of Overstretched DNA Using Fluorescence Polarization Microscopy.
Adam S Backer, Graeme A King, Andreas S Biebricher, Jack W Shepherd, Agnes Noy

J Phys Chem B· August 2021

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PySTACHIO: Python Single-molecule TrAcking stoiCHiometry Intensity and simulatiOn, a flexible, extensible, beginner-friendly and optimized program for analysis of single-molecule microscopy data.
Jack W Shepherd, Ed J Higgins, Adam J M Wollman, Mark C Leake

Comput Struct Biotechnol J· July 2021

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SerraNA: a program to determine nucleic acids elasticity from simulation data.
Victor Velasco-Berrelleza, Matthew Burman, Jack W Shepherd, Mark C Leake, Ramin Golestanian

Phys Chem Chem Phys· September 2020

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The emergence of sequence-dependent structural motifs in stretched, torsionally constrained DNA.
Jack W Shepherd, Robert J Greenall, Matt I J Probert, Agnes Noy, Mark C Leake

Nucleic Acids Res· February 2020

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Single-molecule techniques in biophysics: a review of the progress in methods and applications.
Helen Miller, Zhaokun Zhou, Jack Shepherd, Adam J M Wollman, Mark C Leake

Rep Prog Phys· February 2018

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Patient-centric? Third-party payers interfere.
Jack Shepherd

J Fam Pract· April 2012

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