Publications by authors named "Jaclyn Hechtman"

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Comparison of breast and gastric HER2 immunohistochemistry (IHC) scoring criteria in the assessment of endometrial carcinoma.
Rachel L Furuya, Whitney Grither, Mark G Evans, Sharon Wu, Jaclyn F Hechtman

Gynecol Oncol· November 2025

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GPSai: A Clinically Validated AI Tool for Tissue of Origin Prediction during Routine Tumor Profiling.
Hassan Ghani, Anthony Helmstetter, Jennifer R Ribeiro, Todd Maney, Stephanie Rock, Jaclyn Hechtman

Cancer Res Commun· September 2025

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Sarcoid-like reactions in patients treated with checkpoint inhibitors for advanced solid tumors.
Ian Nykaza, Yonina R Murciano-Goroff, Antoine Desilets, Guilherme Harada, Michael A Postow, Jaclyn F Hechtman

Oncologist· May 2025

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Evidence for Unified Assessment Criteria of HER2 Immunohistochemistry in Colorectal Carcinoma.
Mark G Evans, Harris B Krause, Joanne Xiu, Andrew Elliott, Emil Lou, Jaclyn F Hechtman

Mod Pathol· February 2025

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Charting the Genomic Frontier: 25 Years of Evolution and Future Prospects in Molecular Diagnostics for Solid Tumors.
Jaclyn F Hechtman, Brett Baskovich, Amber Fussell, Katherine B Geiersbach, J Bryan Iorgulescu

J Mol Diagn· January 2025

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A deep multiple instance learning framework improves microsatellite instability detection from tumor next generation sequencing.
John Ziegler, Jaclyn F Hechtman, Satshil Rana, Ryan N Ptashkin, Gowtham Jayakumaran

Nat Commun· January 2025

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SWI/SNF Complex-Deficient Undifferentiated Carcinoma of the Pancreas: Clinicopathologic and Genomic Analysis.
Aslihan Yavas, Kerem Ozcan, N Volkan Adsay, Serdar Balci, Zeynep C Tarcan, Jaclyn F Hechtman

Mod Pathol· November 2024

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Analysis of Concordance Between Next-Generation Sequencing Assessment of Microsatellite Instability and Immunohistochemistry-Mismatch Repair From Solid Tumors.
Rouba Ali-Fehmi, Harris Benjamin Krause, Robert T Morris, John J Wallbillich, Logan Corey, Jaclyn Hechtman

JCO Precis Oncol· October 2024

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Molecular Approach to Colorectal Carcinoma: Current Evidence and Clinical Application.
Cameron Beech, Jaclyn F Hechtman

Clin Lab Med· June 2024

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Microsatellite Instability and Mismatch Repair Deficiency Define a Distinct Subset of Lung Cancers Characterized by Smoking Exposure, High Tumor Mutational Burden, and Recurrent Somatic MLH1 Inactivation.
Soo-Ryum Yang, Erika Gedvilaite, Ryan Ptashkin, Jason Chang, John Ziegler, Jaclyn F Hechtman

J Thorac Oncol· March 2024

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Her2 low (but not negative): the newest biomarker on the block for gastro-oesophageal adenocarcinoma.
Jaclyn Frances Hechtman

J Clin Pathol· December 2023

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Determinants of Survival with Combined HER2 and PD-1 Blockade in Metastatic Esophagogastric Cancer.
Steven B Maron, Walid Chatila, Henry Walch, Joanne F Chou, Nicholas Ceglia, Jaclyn F Hechtman

Clin Cancer Res· September 2023

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Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers.
Walid K Chatila, Henry Walch, Jaclyn F Hechtman, Sydney M Moyer, Valeria Sgambati

Nat Commun· January 2023

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ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1.
Wenjing Su, Radha Mukherjee, Rona Yaeger, Jieun Son, Jianing Xu, Jaclyn Hechtman

Mol Cell· July 2022

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Recurrent Loss of Heterozygosity in Pancreatic Neuroendocrine Tumors.
Megan Parilla, David Chapel, Jaclyn F Hechtman, Pankhuri Wanjari, Tony El Jabbour

Am J Surg Pathol· June 2022

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NTRK insights: best practices for pathologists.
Jaclyn F Hechtman

Mod Pathol· March 2022

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Same-Cell Co-Occurrence of RAS Hotspot and BRAF V600E Mutations in Treatment-Naive Colorectal Cancer.
Rodrigo Gularte-Mérida, Shaleigh Smith, Anita S Bowman, Arnaud da Cruz Paula, Walid Chatila, Jaclyn F Hechtman

JCO Precis Oncol· March 2022

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Defining and Targeting Esophagogastric Cancer Genomic Subsets With Patient-Derived Xenografts.
Ryan H Moy, Henry S Walch, Marissa Mattar, Walid K Chatila, Daniela Molena, Jaclyn F Hechtman

JCO Precis Oncol· February 2022

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Diagnostic testing approaches for the identification of patients with TRK fusion cancer prior to enrollment in clinical trials investigating larotrectinib.
Erin R Rudzinski, Jaclyn Hechtman, Sinchita Roy-Chowdhuri, Marion Rudolph, Christina M Lockwood

Cancer Genet· January 2022

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Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack.
Zhikai Wang, Philip Moresco, Ran Yan, Jiayun Li, Ya Gao, Jaclyn F Hechtman

Proc Natl Acad Sci U S A· January 2022

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EGFR Amplification in Metastatic Colorectal Cancer.
Giovanni Randon, Rona Yaeger, Jaclyn F Hechtman, Paolo Manca, Giovanni Fucà

J Natl Cancer Inst· November 2021

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Molecular Approach to Colorectal Carcinoma: Current Evidence and Clinical Application.
Cameron Beech, Jaclyn F Hechtman

Surg Pathol Clin· September 2021

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Prevalence of Germline Alterations on Targeted Tumor-Normal Sequencing of Esophagogastric Cancer.
Geoffrey Y Ku, Yelena Kemel, Steve B Maron, Joanne F Chou, Vignesh Ravichandran, Jaclyn F Hechtman

JAMA Netw Open· July 2021

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Next-Generation Sequencing of 487 Esophageal Adenocarcinomas Reveals Independently Prognostic Genomic Driver Alterations and Pathways.
Smita Sihag, Samuel C Nussenzweig, Henry S Walch, Meier Hsu, Kay See Tan, Jaclyn Hechtman

Clin Cancer Res· June 2021

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Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS.
A Rose Brannon, Gowtham Jayakumaran, Monica Diosdado, Juber Patel, Anna Razumova, Jaclyn F Hechtman

Nat Commun· June 2021

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