Publications by authors named "Jacob A Mayfield"

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Mapping unsolved lipidomes accelerates lipid discovery in major bacterial pathogens.
Yashodhan M Nair, Aruna R Menon, Zonghao Lin, Michiel R L Vossenberg, Vanisha Munsamy-Govender, Jacob A Mayfield

bioRxiv· November 2025

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Sideways lipid presentation by the antigen-presenting molecule CD1c.
Thinh-Phat Cao, Guan-Ru Liao, Tan-Yun Cheng, Yanqiong Chen, Laura Ciacchi, Jacob A Mayfield

bioRxiv· October 2025

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Paired analysis of host and pathogen genomes identifies determinants of human tuberculosis.
Yang Luo, Chuan-Chin Huang, Nicole C Howard, Xin Wang, Qingyun Liu, Jacob A Mayfield

Nat Commun· November 2024

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Mycobacteria that cause tuberculosis have retained ancestrally acquired genes for the biosynthesis of chemically diverse terpene nucleosides.
Jacob A Mayfield, Sahadevan Raman, Alexandrea K Ramnarine, Vivek K Mishra, Annie D Huang

PLoS Biol· September 2024

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CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.
Shouxiong Huang, Adam Shahine, Tan-Yun Cheng, Yi-Ling Chen, Soo Weei Ng, Jacob A Mayfield

Cell· October 2023

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Tuberculostearic Acid Controls Mycobacterial Membrane Compartmentalization.
Malavika Prithviraj, Takehiro Kado, Jacob A Mayfield, David C Young, Annie D Huang

mBio· April 2023

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Biotin-dependent cell envelope remodelling is required for Mycobacterium abscessus survival in lung infection.
Mark R Sullivan, Kerry McGowen, Qiang Liu, Chidiebere Akusobi, David C Young, Jacob A Mayfield

Nat Microbiol· March 2023

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A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages.
Melissa Bedard, Sanne van der Niet, Elliott M Bernard, Gregory Babunovic, Tan-Yun Cheng, Jacob A Mayfield

J Clin Invest· March 2023

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Genetic modifiers regulating DNA replication and double-strand break repair are associated with differences in mammary tumors in mouse models of Li-Fraumeni syndrome.
Prabin Dhangada Majhi, Nicholas B Griner, Jacob A Mayfield, Shannon Compton, Jeffrey J Kane

Oncogene· August 2021

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Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products.
Sarah Nicolai, Marcin Wegrecki, Tan-Yun Cheng, Elvire A Bourgeois, Rachel N Cotton, Jacob A Mayfield

Sci Immunol· January 2020

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Mycobacterium tuberculosis releases an antacid that remodels phagosomes.
Jeffrey Buter, Tan-Yun Cheng, Marwan Ghanem, Anita E Grootemaat, Sahadevan Raman, Jacob A Mayfield

Nat Chem Biol· September 2019

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Gene expression signature of atypical breast hyperplasia and regulation by SFRP1.
Kelly J Gregory, Amy L Roberts, Erin M Conlon, Jacob A Mayfield, Mary J Hagen

Breast Cancer Res· June 2019

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Discovery of trehalose phospholipids reveals functional convergence with mycobacteria.
Peter Reinink, Jeffrey Buter, Vivek K Mishra, Eri Ishikawa, Tan-Yun Cheng, Jacob A Mayfield

J Exp Med· April 2019

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Demethylmenaquinone Methyl Transferase Is a Membrane Domain-Associated Protein Essential for Menaquinone Homeostasis in .
Julia Puffal, Jacob A Mayfield, D Branch Moody, Yasu S Morita

Front Microbiol· December 2018

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T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.
Kwok S Wun, Josephine F Reijneveld, Tan-Yun Cheng, Kristin Ladell, Adam P Uldrich, Jacob A Mayfield

Nat Immunol· April 2018

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Multisystem Analysis of Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface.
Xavier Carette, John Platig, David C Young, Michaela Helmel, Albert T Young, Jacob A Mayfield

mBio· March 2018

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The cell envelope-associated phospholipid-binding protein LmeA is required for mannan polymerization in mycobacteria.
Kathryn C Rahlwes, Stephanie A Ha, Daisuke Motooka, Jacob A Mayfield, Lisa R Baumoel

J Biol Chem· October 2017

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Spatially distinct and metabolically active membrane domain in mycobacteria.
Jennifer M Hayashi, Chu-Yuan Luo, Jacob A Mayfield, Tsungda Hsu, Takeshi Fukuda

Proc Natl Acad Sci U S A· May 2016

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Surrogate genetics and metabolic profiling for characterization of human disease alleles.
Jacob A Mayfield, Meara W Davies, Dago Dimster-Denk, Nick Pleskac, Sean McCarthy

Genetics· April 2012

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Genetic control of immune cell types in fungal disease.
Jacob A Mayfield, Mary F Fontana, Jasper Rine

Proc Natl Acad Sci U S A· December 2010

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Histoplasma requires SID1, a member of an iron-regulated siderophore gene cluster, for host colonization.
Lena H Hwang, Jacob A Mayfield, Jasper Rine, Anita Sil

PLoS Pathog· April 2008

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