Publications by authors named "Jacob Boyer"

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PAX3-FOXO1 Drives Targetable Cell State-Dependent Metabolic Vulnerabilities in Rhabdomyosarcoma.
Katrina I Paras, Julia S Brunner, Angela M Montero, Jacob A Boyer, Benjamin T Jackson

Cancer Res· December 2025

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Oxidative pentose phosphate pathway is required for T cell activation and antitumor immunity.
Zihong Chen, Kellen L Olszewski, Rolf-Peter Ryseck, Xincheng Xu, Jacob A Boyer

Proc Natl Acad Sci U S A· December 2025

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Anti-uPAR CAR T cells reverse and prevent aging-associated defects in intestinal regeneration and fitness.
Onur Eskiocak, Joseph Gewolb, Vyom Shah, James A Rouse, Saria Chowdhury, Jacob A Boyer

Nat Aging· November 2025

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eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer.
Jacob A Boyer, Ezra Y Rosen, Malvika Sharma, Madeline A Dorso, Nicholas Mai

Proc Natl Acad Sci U S A· July 2025

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Metabolism of epigenetic ribonucleosides leads to nucleolar stress and cytotoxicity.
Xuemeng Sun, Anita Donlic, Jacob A Boyer, Neal Reddy, Clifford P Brangwynne

bioRxiv· June 2025

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Micromapping (μMap) of HER2 Across Human Breast Cancers: Photocatalytic Proximity Labeling Identifies Primary Resistance Mechanisms and Functional Interactors.
Steve D Knutson, Jacob A Boyer, Danielle C Morgan, Johannes Großkopf, Joshua D Rabinowitz

bioRxiv· June 2025

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Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration.
Sunyana Gadal, Jacob A Boyer, Simon F Roy, Noah A Outmezguine, Malvika Sharma

Cancer Res· May 2025

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Microbiome metabolism of dietary phytochemicals controls the anticancer activity of PI3K inhibitors.
Asael Roichman, Qianying Zuo, Sunghoon Hwang, Wenyun Lu, Ricardo A Cordova, Jacob A Boyer

Cell· May 2025

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GaAs Solar Cells Grown Directly on V-Groove Si Substrates.
Theresa E Saenz, Jacob Boyer, John S Mangum, Anica N Neumann, Jennifer Selvidge

ACS Appl Mater Interfaces· January 2025

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PAX3-FOXO1 drives targetable cell state-dependent metabolic vulnerabilities in rhabdomyosarcoma.
Katrina I Paras, Julia S Brunner, Jacob A Boyer, Angela M Montero, Benjamin T Jackson

bioRxiv· January 2025

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Integrative Computational Framework, , Links Mutated Driver Genes to Expression Dysregulation Across 19 Cancer Types.
Sara Geraghty, Jacob A Boyer, Mahya Fazel-Zarandi, Nibal Arzouni, Rolf-Peter Ryseck

bioRxiv· November 2024

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Combined inhibition of KRAS and mTORC1 kinase is synergistic in non-small cell lung cancer.
Hidenori Kitai, Philip H Choi, Yu C Yang, Jacob A Boyer, Adele Whaley

Nat Commun· July 2024

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A Ketogenic Diet Sensitizes Pancreatic Cancer to Inhibition of Glutamine Metabolism.
Omid Hajihassani, Mehrdad Zarei, Asael Roichman, Alexander Loftus, Christina S Boutros, Jacob Boyer

bioRxiv· July 2024

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eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer.
Jacob A Boyer, Malvika Sharma, Madeline A Dorso, Nicholas Mai, Corina Amor

bioRxiv· May 2024

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In Situ Smoothing of Facets on Spalled GaAs(100) Substrates during OMVPE Growth of III-V Epilayers, Solar Cells, and Other Devices: The Impact of Surface Impurities/Dopants.
William E McMahon, Anna K Braun, Allison N Perna, Pablo G Coll, Kevin L Schulte, Jacob T Boyer

Cryst Growth Des· April 2024

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Tumorigenesis driven by the BRAF oncoprotein requires secondary mutations that overcome its feedback inhibition of migration and invasion.
Sunyana Gadal, Jacob A Boyer, Simon F Roy, Noah A Outmezguine, Malvika Sharma

bioRxiv· April 2024

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Author Correction: Senolytic CAR T cells reverse senescence-associated pathologies.
Corina Amor, Judith Feucht, Josef Leibold, Yu-Jui Ho, Changyu Zhu, Jacob A Boyer

Nature· March 2024

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Senolytic CAR T cells reverse aging-associated defects in intestinal regeneration and fitness.
Onur Eskiocak, Saria Chowdhury, Vyom Shah, Emmanuella Nnuji-John, Charlie Chung, Jacob A Boyer

bioRxiv· March 2024

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A Druggable FOXA1-Glucocorticoid Receptor Transcriptional Axis Drives Tumor Growth in a Subset of Non-Small Cell Lung Cancer.
M Dorso, Payal T Patel, Aleksandr Pankov, Jacob A Boyer, Rajesh K Soni

Cancer Res Commun· September 2023

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Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction.
Corina Amor, Inés Fernández-Maestre, Saria Chowdhury, Yu-Jui Ho, Sandeep Nadella, Jacob A Boyer

Res Sq· September 2023

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P-selectin-targeted nanocarriers induce active crossing of the blood-brain barrier via caveolin-1-dependent transcytosis.
Daniel E Tylawsky, Hiroto Kiguchi, Jake Vaynshteyn, Jeffrey Gerwin, Janki Shah, Jacob A Boyer

Nat Mater· March 2023

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Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth.
Bianca J Lee, Jacob A Boyer, G Leslie Burnett, Arun P Thottumkara, Nidhi Tibrewal

Nat Chem Biol· November 2021

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Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth.
Bianca J Lee, Jacob A Boyer, G Leslie Burnett, Arun P Thottumkara, Nidhi Tibrewal

Nat Chem Biol· October 2021

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Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth.
Bianca J Lee, Jacob A Boyer, G Leslie Burnett, Arun P Thottumkara, Nidhi Tibrewal

Nat Chem Biol· August 2021

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