Publications by authors named "Jacob D Jaffe"

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Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data.
Dušica Vidović, Behrouz Shamsaei, Stephan C Schürer, Phillip Kogan, Szymon Chojnacki, Jacob D Jaffe

Mol Cell Proteomics· July 2025

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Corrigendum to "Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data".
Dušica Vidović, Behrouz Shamsaei, Stephan C Schürer, Phillip Kogan, Szymon Chojnacki, Jacob D Jaffe

Mol Cell Proteomics· July 2025

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KDM4C inhibition blocks tumor growth in basal breast cancer by promoting cathepsin L-mediated histone H3 cleavage.
Zheqi Li, Guillermo Peluffo, Laura E Stevens, Xintao Qiu, Marco Seehawer, Jacob D Jaffe

Nat Genet· June 2025

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Identifying mitigating strategies for endothelial cell dysfunction and hypertension in response to VEGF receptor inhibitors.
Nicholas D Camarda, Qing Lu, Dawn M Meola, Joshua J Man, Zeyuan Song, Jacob D Jaffe, Iris Z Jaffe

Clin Sci (Lond)· September 2024

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Heterogeneity and transcriptional drivers of triple-negative breast cancer.
Bojana Jovanović, Daniel Temko, Laura E Stevens, Marco Seehawer, Anne Fassl, Jacob D Jaffe

Cell Rep· December 2023

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Smooth muscle mineralocorticoid receptor as an epigenetic regulator of vascular ageing.
Jaime Ibarrola, Seung Kyum Kim, Qing Lu, Jennifer J DuPont, Amanda Creech, Jacob D Jaffe, Iris Z Jaffe

Cardiovasc Res· January 2023

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JAK-STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States.
Laura E Stevens, Guillermo Peluffo, Xintao Qiu, Daniel Temko, Anne Fassl, Jacob D Jaffe

Cancer Res· January 2023

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Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors.
Hiruy S Meharena, Asaf Marco, Vishnu Dileep, Elana R Lockshin, Grace Y Akatsu, Jacob D Jaffe

Cell Stem Cell· January 2022

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Proteomic profiling dataset of chemical perturbations in multiple biological backgrounds.
Deborah O Dele-Oni, Karen E Christianson, Shawn B Egri, Alvaro Sebastian Vaca Jacome, Katherine C DeRuff, Jacob D Jaffe

Sci Data· August 2021

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Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity.
Gabriel K Griffin, Jingyi Wu, Arvin Iracheta-Vellve, James C Patti, Jeffrey Hsu, Jacob D Jaffe

Nature· July 2021

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Noncanonical open reading frames encode functional proteins essential for cancer cell survival.
John R Prensner, Oana M Enache, Victor Luria, Karsten Krug, Karl R Clauser, Jacob D Jaffe

Nat Biotechnol· June 2021

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Causal interactions from proteomic profiles: Molecular data meet pathway knowledge.
Özgün Babur, Augustin Luna, Anil Korkut, Funda Durupinar, Metin Can Siper, Jacob D Jaffe

Patterns (N Y)· June 2021

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Author Correction: The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma.
Matthew J McBride, Nazar Mashtalir, Evan B Winter, Hai T Dao, Martin Filipovski, Jacob D Jaffe

Nat Struct Mol Biol· January 2021

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Dual protease type XIII/pepsin digestion offers superior resolution and overlap for the analysis of histone tails by HX-MS.
James Mullahoo, Terry Zhang, Karl Clauser, Steven A Carr, Jacob D Jaffe

Methods· December 2020

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Avant-garde: an automated data-driven DIA data curation tool.
Alvaro Sebastian Vaca Jacome, Ryan Peckner, Nicholas Shulman, Karsten Krug, Katherine C DeRuff, Jacob D Jaffe

Nat Methods· December 2020

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The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma.
Matthew J McBride, Nazar Mashtalir, Evan B Winter, Hai T Dao, Martin Filipovski, Jacob D Jaffe

Nat Struct Mol Biol· September 2020

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Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.
Shaokun Shu, Hua-Jun Wu, Jennifer Y Ge, Rhamy Zeid, Isaac S Harris, Jacob D Jaffe

Mol Cell· June 2020

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Phosphorylation of RAB7 by TBK1/IKKε Regulates Innate Immune Signaling in Triple-Negative Breast Cancer.
Jessica L Ritter, Zehua Zhu, Tran C Thai, Navin R Mahadevan, Philipp Mertins, Jacob D Jaffe

Cancer Res· January 2020

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Chasing Tails: Cathepsin-L Improves Structural Analysis of Histones by HX-MS.
Malvina Papanastasiou, James Mullahoo, Katherine C DeRuff, Besnik Bajrami, Ioannis Karageorgos, Jacob D Jaffe

Mol Cell Proteomics· October 2019

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Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma.
Pratiti Bandopadhayay, Federica Piccioni, Ryan O'Rourke, Patricia Ho, Elizabeth M Gonzalez, Jacob D Jaffe

Nat Commun· June 2019

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Next-generation characterization of the Cancer Cell Line Encyclopedia.
Mahmoud Ghandi, Franklin W Huang, Judit Jané-Valbuena, Gregory V Kryukov, Christopher C Lo, Jacob D Jaffe

Nature· May 2019

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Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.
Abhishek A Chakraborty, Tuomas Laukka, Matti Myllykoski, Alison E Ringel, Matthew A Booker, Jacob D Jaffe

Science· March 2019

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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
Kunihiko Hinohara, Hua-Jun Wu, Sébastien Vigneau, Thomas O McDonald, Kyomi J Igarashi, Jacob D Jaffe

Cancer Cell· February 2019

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Initial Guidelines for Manuscripts Employing Data-independent Acquisition Mass Spectrometry for Proteomic Analysis.
Robert J Chalkley, Michael J MacCoss, Jacob D Jaffe, Hannes L Röst

Mol Cell Proteomics· January 2019

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