Publications by authors named "Jacob Fredsoe"

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Training and validation of a novel 14-gene expression signature associated with prostate cancer metastasis and postoperative recurrence.
Eva F Jensby, Søren Klingenberg, Jacob Fredsøe, Kia E Fonfara, Benedicte P Ulhøi

Int J Cancer· March 2026

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Up-regulation of intra-tumour LDLR gene expression is associated with statin treatment and better prostate cancer prognosis.
Kia Eistrup Fonfara, Jacob Fredsøe, Benedicte Ulhøi, Signe Borgquist, Michael Borre

Acta Oncol· October 2025

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Deep targeted sequencing of circulating tumor DNA to inform treatment in patients with metastatic castration-resistant prostate cancer.
Maibritt Nørgaard, Maria Rusan, Karoline Kondrup, Ea Marie Givskov Sørensen, Simone Weiss

J Exp Clin Cancer Res· April 2025

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Stroma-specific gene expression signature identifies prostate cancer subtype with high recurrence risk.
Martin Rasmussen, Jacob Fredsøe, Paul Vinu Salachan, Marcus Pii Lunau Blanke, Stine Hesselby Larsen

NPJ Precis Oncol· February 2024

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Danish Prostate Cancer Consortium Study 1 (DPCC-1) protocol: Multicentre prospective validation of the urine-based three-microRNA biomarker model uCaP.
Jacob Fredsøe, Eske Glud, Lars Boesen, Vibeke Løgager, Mads Hvid Poulsen

BMJ Open· November 2023

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Results from the PRIMA Trial: Comparison of the STHLM3 Test and Prostate-specific Antigen in General Practice for Detection of Prostate Cancer in a Biopsy-naïve Population.
Jacob Fredsøe, Mads Sandahl, Peter Vedsted, Jørgen Bjerggaard Jensen, Benedicte Parm Ulhøi

Eur Urol Oncol· October 2023

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Prognostic Value of Low-Pass Whole Genome Sequencing of Circulating Tumor DNA in Metastatic Castration-Resistant Prostate Cancer.
Maibritt Nørgaard, Marianne T Bjerre, Jacob Fredsøe, Søren Vang, Jørgen B Jensen

Clin Chem· April 2023

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Cost-Effectiveness Analysis of Stockholm 3 Testing Compared to PSA as the Primary Blood Test in the Prostate Cancer Diagnostic Pathway: A Decision Tree Approach.
Bettina Wulff Risør, Nasrin Tayyari Dehbarez, Jacob Fredsøe, Karina Dalsgaard Sørensen, Bodil Ginnerup Pedersen

Appl Health Econ Health Policy· November 2022

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Recurrence rate after radical prostatectomy following primary staging of high-risk prostate cancer with Ga-PSMA PET/CT.
Søren Klingenberg, Jacob Fredsøe, Karina D Sørensen, Benedicte P Ulhøi, Michael Borre

Acta Oncol· October 2022

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A genome-wide CRISPR-Cas9 knockout screen identifies novel PARP inhibitor resistance genes in prostate cancer.
Malene Blond Ipsen, Ea Marie Givskov Sørensen, Emil Aagaard Thomsen, Simone Weiss, Jakob Haldrup

Oncogene· September 2022

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Predicting Grade group 2 or higher cancer at prostate biopsy by 4Kscore in blood and uCaP microRNA model in urine.
Jacob Fredsøe, Martin Rasmussen, Amy L Tin, Andrew J Vickers, Michael Borre

Sci Rep· September 2022

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Independent validation of a pre-specified four-kallikrein marker model for prediction of adverse pathology and biochemical recurrence.
Martin Rasmussen, Jacob Fredsøe, Amy L Tin, Andrew J Vickers, Benedicte Ulhøi

Br J Cancer· April 2022

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The transcriptional landscape and biomarker potential of circular RNAs in prostate cancer.
Emma Bollmann Hansen, Jacob Fredsøe, Trine Line Hauge Okholm, Benedicte Parm Ulhøi, Søren Klingenberg

Genome Med· January 2022

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Microbiota of the prostate tumor environment investigated by whole-transcriptome profiling.
Paul Vinu Salachan, Martin Rasmussen, Jacob Fredsøe, Benedicte Ulhøi, Michael Borre

Genome Med· January 2022

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Immune cell analyses of the tumor microenvironment in prostate cancer highlight infiltrating regulatory T cells and macrophages as adverse prognostic factors.
Line B Andersen, Maibritt Nørgaard, Martin Rasmussen, Jacob Fredsøe, Michael Borre

J Pathol· October 2021

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High-Throughput and Automated Acoustic Trapping of Extracellular Vesicles to Identify microRNAs With Diagnostic Potential for Prostate Cancer.
Anson Ku, Jacob Fredsøe, Karina D Sørensen, Michael Borre, Mikael Evander

Front Oncol· March 2021

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Ga-PSMA PET/CT for Primary Lymph Node and Distant Metastasis NM Staging of High-Risk Prostate Cancer.
Søren Klingenberg, Mads R Jochumsen, Benedicte P Ulhøi, Jacob Fredsøe, Karina D Sørensen

J Nucl Med· February 2021

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A genetic risk assessment for prostate cancer influences patients' risk perception and use of repeat PSA testing: a cross-sectional study in Danish general practice.
Jacob Fredsøe, Pia Kirkegaard, Adrian Edwards, Peter Vedsted, Karina Dalsgaard Sørensen

BJGP Open· June 2020

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Epigenetic Analysis of Circulating Tumor DNA in Localized and Metastatic Prostate Cancer: Evaluation of Clinical Biomarker Potential.
Marianne Trier Bjerre, Maibritt Nørgaard, Ole Halfdan Larsen, Sarah Østrup Jensen, Siri H Strand

Cells· May 2020

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Profiling of Circulating microRNAs in Prostate Cancer Reveals Diagnostic Biomarker Potential.
Jacob Fredsøe, Anne K I Rasmussen, Peter Mouritzen, Marianne T Bjerre, Peter Østergren

Diagnostics (Basel)· March 2020

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The effect of assessing genetic risk of prostate cancer on the use of PSA tests in primary care: A cluster randomized controlled trial.
Jacob Fredsøe, Jan Koetsenruyter, Peter Vedsted, Pia Kirkegaard, Michael Væth

PLoS Med· February 2020

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Elevated miR-615-3p Expression Predicts Adverse Clinical Outcome and Promotes Proliferation and Migration of Prostate Cancer Cells.
Emma B Laursen, Jacob Fredsøe, Linnéa Schmidt, Siri H Strand, Helle Kristensen

Am J Pathol· December 2019

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A five-microRNA model (pCaP) for predicting prostate cancer aggressiveness using cell-free urine.
Jacob Fredsøe, Anne K I Rasmussen, Peter Mouritzen, Michael Borre, Torben Ørntoft

Int J Cancer· November 2019

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Independent Validation of a Diagnostic Noninvasive 3-MicroRNA Ratio Model () for Prostate Cancer in Cell-Free Urine.
Jacob Fredsøe, Anne K I Rasmussen, Emma B Laursen, Yunpeng Cai, Kenneth A Howard

Clin Chem· April 2019

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Aberrant , , and Hypermethylation has Potential as a Prognostic Biomarker for Prostate Cancer.
Marianne T Bjerre, Siri H Strand, Maibritt Nørgaard, Helle Kristensen, Anne Ki Rasmussen

Int J Mol Sci· March 2019

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