Publications by authors named "Jacob Grunler"

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Alterations in the IGF-System and Antioxidant Biomarkers in Young Brazilian Adults with Type 1 Diabetes: An Analysis of Cardiovascular Risk Factors.
Michael Tekle, Diane Meyre Rassi, Eduardo Antonio Donadi, Jacob Grunler, Gustav Dallner

Antioxidants (Basel)· December 2025

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Maternal diabetes programs sexually dimorphic early-onset cardiovascular dysfunction in metabolically healthy offspring.
Allan Zhao, Yuxia Wei, Eftychia Kontidou, Ali Mahdi, Paulo R Jannig

Cell Rep Med· November 2025

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Appropriate glycemic management protects the germline but not the uterine environment in hyperglycemia.
Allan Zhao, Hong Jiang, Arturo Reyes Palomares, Alice Larsson, Wenteng He

EMBO Rep· April 2024

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Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes.
Xiaowei Zheng, Sampath Narayanan, Cheng Xu, Sofie Eliasson Angelstig, Jacob Grünler

Elife· February 2022

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DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance.
Juan Zhang, Graciela Terán, Mihaela Popa, Harsha Madapura, Marcus James Graeme Watson Ladds

iScience· May 2021

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miR-19a/b and miR-20a Promote Wound Healing by Regulating the Inflammatory Response of Keratinocytes.
Dongqing Li, Hongmei Peng, Le Qu, Pehr Sommar, Aoxue Wang

J Invest Dermatol· March 2021

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HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism.
Sampath Narayanan, Sofie Eliasson Angelstig, Cheng Xu, Jacob Grünler, Allan Zhao

Commun Biol· December 2020

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Triggering of a Dll4-Notch1 loop impairs wound healing in diabetes.
Xiaowei Zheng, Sampath Narayanan, Vivekananda Gupta Sunkari, Sofie Eliasson, Ileana Ruxandra Botusan

Proc Natl Acad Sci U S A· April 2019

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Deficiency of liver-derived insulin-like growth factor-I (IGF-I) does not interfere with the skin wound healing rate.
Ileana Ruxandra Botusan, Xiaowei Zheng, Sampath Narayanan, Jacob Grünler, Vivekananda Gupta Sunkari

PLoS One· June 2018

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MicroRNA-132 with Therapeutic Potential in Chronic Wounds.
Xi Li, Dongqing Li, Aoxue Wang, Tongbin Chu, Warangkana Lohcharoenkal

J Invest Dermatol· December 2017

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Coenzyme Q10 and oxidative stress, the association with peripheral sensory neuropathy and cardiovascular disease in type 2 diabetes mellitus.
Elisabete Forsberg, Cheng Xu, Jacob Grünler, Johan Frostegård, Michael Tekle

J Diabetes Complications· September 2016

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Glutaredoxin mediated redox effects of coenzyme Q10 treatment in type 1 and type 2 diabetes patients.
Sergio J Montano, Jacob Grünler, Deepika Nair, Michael Tekle, Aristi P Fernandes

BBA Clin· December 2015

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MicroRNA-132 enhances transition from inflammation to proliferation during wound healing.
Dongqing Li, Aoxue Wang, Xi Liu, Florian Meisgen, Jacob Grünler

J Clin Invest· August 2015

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Effects of IGFBP-1 and IGFBP-2 and their fragments on migration and IGF-induced proliferation of human dermal fibroblasts.
Katrin Brandt, Jacob Grünler, Kerstin Brismar, Jing Wang

Growth Horm IGF Res· February 2015

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Selective blockade of estrogen receptor beta improves wound healing in diabetes.
Vivekananda Gupta Sunkari, Ileana R Botusan, Octavian Savu, Jacob Grünler, Xiaowei Zheng

Endocrine· June 2014

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Coenzyme Q10 prevents peripheral neuropathy and attenuates neuron loss in the db-/db- mouse, a type 2 diabetes model.
Tie-Jun Sten Shi, Ming-Dong Zhang, Hugo Zeberg, Johanna Nilsson, Jacob Grünler

Proc Natl Acad Sci U S A· January 2013

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Carnosine enhances diabetic wound healing in the db/db mouse model of type 2 diabetes.
Ishrath Ansurudeen, Vivekananda Gupta Sunkari, Jacob Grünler, Verena Peters, Claus Peter Schmitt

Amino Acids· July 2012

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Stability of mitochondrial DNA against reactive oxygen species (ROS) generated in diabetes.
Octavian Savu, Vivekananda Gupta Sunkari, Ileana Ruxandra Botusan, Jacob Grünler, Andrej Nikoshkov

Diabetes Metab Res Rev· July 2011

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Stabilization of HIF-1alpha is critical to improve wound healing in diabetic mice.
Ileana Ruxandra Botusan, Vivekananda Gupta Sunkari, Octavian Savu, Anca Irinel Catrina, Jacob Grünler

Proc Natl Acad Sci U S A· December 2008

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Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants.
Karolina Skorupinska-Tudek, Jaroslaw Poznanski, Jacek Wojcik, Tomasz Bienkowski, Izabela Szostkiewicz, Jacob Grunler

J Biol Chem· July 2008

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Isolation and functional expression of human COQ2, a gene encoding a polyprenyl transferase involved in the synthesis of CoQ.
Margareta Forsgren, Anneli Attersand, Staffan Lake, Jacob Grünler, Ewa Swiezewska

Biochem J· September 2004

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Investigation of regulatory mechanisms in coenzyme Q metabolism.
Jacob Grünler, Gustav Dallner

Methods Enzymol· April 2004

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Gender-specific pattern of insulin-like growth factor-binding protein-3 protease activity in mouse thyroid.
Jing Wang, Jacob Grünler, Moira S Lewitt

Endocrinology· March 2004

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