Publications by authors named "Jacob Junco"

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Efficacy of NAMPT inhibition in T-cell acute lymphoblastic leukemia.
Chelsea Vrana, Matthew Zhang, Max Rochette, Michelle Alozie, Hailey Oviedo, Jacob J Junco

PLoS One· June 2025

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Co-targeting of the thymic stromal lymphopoietin receptor to decrease immunotherapeutic resistance in CRLF2-rearranged Ph-like and Down syndrome acute lymphoblastic leukemia.
Tommaso Balestra, Lisa M Niswander, Asen Bagashev, Joseph P Loftus, Savannah L Ross, Jacob J Junco

Leukemia· March 2025

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Ultra-low extracorporeal volume microfluidic leukapheresis is safe and effective in a rat model.
Mubasher Iqbal, Alexandra L McLennan, Anton Mukhamedshin, Mai T P Dinh, Qisheng Liu, Jacob J Junco

Nat Commun· February 2025

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A transgenic mouse model of Down syndrome acute lymphoblastic leukemia identifies targetable vulnerabilities.
Jacob J Junco, Max Rochette, Michelle Alozie, Raushan Rashid, Maci Terrell

Haematologica· December 2024

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Genomic landscape of Down syndrome-associated acute lymphoblastic leukemia.
Zhenhua Li, Ti-Cheng Chang, Jacob J Junco, Meenakshi Devidas, Yizhen Li

Blood· July 2023

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CRLF2 overexpression results in reduced B-cell differentiation and upregulated E2F signaling in the Dp16 mouse model of Down syndrome.
Jacob J Junco, Barry Zorman, Vincent U Gant, Jaime Muñoz, H Daniel Lacorazza

Exp Hematol· June 2022

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Defining the transcriptional control of pediatric AML highlights RARA as a superenhancer-regulated druggable dependency.
Monika W Perez, Oscar Sias-Garcia, Alfred Daramola, Helen Wei, Maci Terrell, Jacob J Junco

Blood Adv· December 2021

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Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia.
Taylor J Chen, Wa Du, Jacob J Junco, Cory Seth Bridges, Ye Shen

Oncotarget· August 2021

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An Mb1-Cre-driven oncogenic Kras mutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance.
Jacob J Junco, Taylor Chen, Raushan Rashid, Maci Terrell, Vincent U Gant

Leukemia· June 2021

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Enhancer polymorphisms at the IKZF1 susceptibility locus for acute lymphoblastic leukemia impact B-cell proliferation and differentiation in both Down syndrome and non-Down syndrome genetic backgrounds.
Vincent U Gant, Jacob J Junco, Maci Terrell, Raushan Rashid, Karen R Rabin

PLoS One· May 2021

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Metabolomic profiling identifies pathways associated with minimal residual disease in childhood acute lymphoblastic leukaemia.
Jeremy M Schraw, Jacob J Junco, Austin L Brown, Michael E Scheurer, Karen R Rabin

EBioMedicine· October 2019

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Harnessing the gatekeepers of glucocorticoids for chemoprevention of non-melanoma skin cancer.
Anna M Mancha-Ramirez, Xiaoyu Yang, Huiyun Liang, Jacob Junco, Kevin P Lee

Mol Carcinog· January 2019

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Role of AMPK and PPARα in the anti-skin cancer effects of ursolic acid.
Jacob J Junco, Jiyoon Cho, Anna Mancha, Gunjan Malik, Sung-Jen Wei

Mol Carcinog· December 2018

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Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate.
Jiyoon Cho, Okkyung Rho, Jacob Junco, Steve Carbajal, Dionicio Siegel

Cancer Prev Res (Phila)· September 2015

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Ursolic acid and resveratrol synergize with chloroquine to reduce melanoma cell viability.
Jacob J Junco, Anna Mancha-Ramirez, Gunjan Malik, Sung-Jen Wei, Dae Joon Kim

Melanoma Res· April 2015

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Differential effects on lung cancer cell proliferation by agonists of glucocorticoid and PPARα receptors.
Huiyun Liang, Piotr Kowalczyk, Jacob J Junco, Heather L Klug-De Santiago, Gunjan Malik

Mol Carcinog· September 2014

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The effects of dissociated glucocorticoids RU24858 and RU24782 on TPA-induced skin tumor promotion biomarkers in SENCAR mice.
Piotr Kowalczyk, Jacob J Junco, Magdalena C Kowalczyk, Renata Sosnowska, Olga Tolstykh

Mol Carcinog· June 2014

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DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.
Yinghao Zhang, Fang-Mei Chang, Jianjun Huang, Jacob J Junco, Shivani K Maffi

Protein Cell· February 2014

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Resveratrol and P-glycoprotein inhibitors enhance the anti-skin cancer effects of ursolic acid.
Jacob J Junco, Anna Mancha, Gunjan Malik, Sung-Jen Wei, Dae Joon Kim

Mol Cancer Res· December 2013

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Effects of combined phytochemicals on skin tumorigenesis in SENCAR mice.
Magdalena C Kowalczyk, Jacob J Junco, Piotr Kowalczyk, Olga Tolstykh, Margaret Hanausek

Int J Oncol· September 2013

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The possible separation of 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation and hyperplasia by compound A.
Piotr Kowalczyk, Magdalena C Kowalczyk, Jacob J Junco, Olga Tolstykh, Tatsuya Kinjo

Mol Carcinog· June 2013

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