Publications by authors named "Jacob Olsen"

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Activation of Adenosine Monophosphate-Activated Protein Kinase Reduces the Onset of Diet-Induced Hepatocellular Carcinoma in Mice.
Dieter Schmoll, Nicole Ziegler, Benoit Viollet, Marc Foretz, Patrick C Even, Jacob A Olsen

Hepatol Commun· July 2020

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Synthesis of Shld Derivatives, Their Binding to the Destabilizing Domain, and Influence on Protein Accumulation in Transgenic Plants.
Frederik Præstholm Jørgensen, Daniel Madsen, Morten Meldal, Jacob Valdbjørn Olsen, Morten Petersen

J Med Chem· May 2019

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Determination of protonation states of iminosugar-enzyme complexes using photoinduced electron transfer.
Bo Wang, Jacob Ingemar Olsen, Bo W Laursen, Jens Christian Navarro Poulsen, Mikael Bols

Chem Sci· November 2017

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Selenoureido-iminosugars: A new family of multitarget drugs.
Jacob Ingemar Olsen, Gabriela B Plata, José M Padrón, Óscar López, Mikael Bols

Eur J Med Chem· November 2016

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Intraspecific variation of a dominant grass and local adaptation in reciprocal garden communities along a US Great Plains' precipitation gradient: implications for grassland restoration with climate change.
Loretta C Johnson, Jacob T Olsen, Hannah Tetreault, Angel DeLaCruz, Johnny Bryant

Evol Appl· August 2015

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Design, synthesis and in vitro pharmacology of GluK1 and GluK3 antagonists. Studies towards the design of subtype-selective antagonists through 2-carboxyethyl-phenylalanines with substituents interacting with non-conserved residues in the GluK binding sites.
Niklas Sköld, Birgitte Nielsen, Jacob Olsen, Liwei Han, Lars Olsen

Bioorg Med Chem· October 2014

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Environmental and genetic variation in leaf anatomy among populations of Andropogon gerardii (Poaceae) along a precipitation gradient.
Jacob T Olsen, Keri L Caudle, Loretta C Johnson, Sara G Baer, Brian R Maricle

Am J Bot· October 2013

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Eye movement suppression interferes with construction of object-centered spatial reference frames in working memory.
Mikkel Wallentin, Line Burholt Kristensen, Jacob Hedeager Olsen, Andreas Højlund Nielsen

Brain Cogn· December 2011

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Quantifying the electronic effects of carbohydrate hydroxy groups by using aminosugar models.
Christian M Pedersen, Jacob Olsen, Azra B Brka, Mikael Bols

Chemistry· June 2011

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Multipolar interactions in the D pocket of thrombin: large differences between tricyclic imide and lactam inhibitors.
Eliane Schweizer, Anja Hoffmann-Röder, Jacob A Olsen, Paul Seiler, Ulrike Obst-Sander

Org Biomol Chem· June 2006

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A fluorine scan at the catalytic center of thrombin: C--F, C--OH, and C--OMe bioisosterism and fluorine effects on pKa and log D values.
Eliane Schweizer, Anja Hoffmann-Röder, Kaspar Schärer, Jacob A Olsen, Christoph Fäh

ChemMedChem· June 2006

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A fluorine scan of the phenylamidinium needle of tricyclic thrombin inhibitors: effects of fluorine substitution on pKa and binding affinity and evidence for intermolecular C-F...CN interactions.
Jacob Olsen, Paul Seiler, Björn Wagner, Holger Fischer, Thomas Tschopp

Org Biomol Chem· May 2004

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Fluorine interactions at the thrombin active site: protein backbone fragments H-C(alpha)-C=O comprise a favorable C-F environment and interactions of C-F with electrophiles.
Jacob A Olsen, David W Banner, Paul Seiler, Björn Wagner, Thomas Tschopp

Chembiochem· May 2004

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A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions.
Jacob A Olsen, David W Banner, Paul Seiler, Ulrike Obst Sander, Allan D'Arcy

Angew Chem Int Ed Engl· June 2003

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Identification of potent and broad-spectrum antibiotics from SAR studies of a synthetic vancomycin analogue.
Kateri A Ahrendt, Jacob A Olsen, Masahiro Wakao, Joaquim Trias, Jonathan A Ellman

Bioorg Med Chem Lett· May 2003

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