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Publications by authors named "Jacob P Beard"

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Structure-Activity Relationship Study of Splicing Modulators on Hsh155/SF3B1 through Chemical Synthesis and Yeast Genetics.
Jacob P Beard, Sierra L Love, John C Schmitz, Aaron A Hoskins, Kazunori Koide

ACS Med Chem Lett· December 2024


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Synthesis and antiproliferative activity of a tetrahydrofuran analog of FR901464.
Ivanna Pohorilets, Jacob P Beard, Julia L Driscoll, John C Schmitz, Kazunori Koide

Bioorg Med Chem Lett· May 2024


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Synthesis and Conformational Analysis of FR901464-Based RNA Splicing Modulators and Their Synergism in Drug-Resistant Cancers.
Jacob P Beard, Robert K Bressin, Paulo L Markaj, John C Schmitz, Kazunori Koide

J Med Chem· November 2023


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Improved Synthesis of the Amine Fragment of FR901464 and Thailanstatins through the Development of a Convenient -Detosylation Method.
Jacob P Beard, Joseph D Emerson, Alexander S Jacobs, Andrew J O'Grady, James Burrows

J Org Chem· October 2022


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