Publications by authors named "Jacob Packer"

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Infrarenal Aortic Occlusion Causes Endothelial Injury via Mitochondrial Reactive Oxygen Species.
Jessica Friedman, Michael Ghio, Aaron Cotton-Betteridge, Mardeen Karim, Jacob Packer

J Surg Res· May 2025

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EXOSOMES AND MICROVESICLES FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS PROTECTS THE ENDOTHELIAL GLYCOCALYX FROM LPS INJURY.
Sharven Taghavi, Sarah Abdullah, Farhana Shaheen, Jacob Packer, Juan Duchesne

Shock· July 2023

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Succinate metabolism and membrane reorganization drives the endotheliopathy and coagulopathy of traumatic hemorrhage.
Sarah Abdullah, Michael Ghio, Aaron Cotton-Betteridge, Aditya Vinjamuri, Robert Drury, Jacob Packer

Sci Adv· June 2023

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Dimethyl malonate slows succinate accumulation and preserves cardiac function in a swine model of hemorrhagic shock.
Sharven Taghavi, Sarah Abdullah, Eman Toraih, Jacob Packer, Robert H Drury

J Trauma Acute Care Surg· July 2022

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Hemorrhagic Shock and Resuscitation Causes Glycocalyx Shedding and Endothelial Oxidative Stress Preferentially in the Lung and Intestinal Vasculature.
Sarah Abdullah, Mardeen Karim, Mark Legendre, Laura Rodriguez, Jessica Friedman, Jacob Packer

Shock· November 2021

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Interleukin-22 mitigates acute respiratory distress syndrome (ARDS).
Sharven Taghavi, Olan Jackson-Weaver, Sarah Abdullah, Alanna Wanek, Robert Drury, Jacob Packer

PLoS One· November 2021

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Hypoxia/reoxygenation decreases endothelial glycocalyx via reactive oxygen species and calcium signaling in a cellular model for shock.
Olan Jackson-Weaver, Jessica K Friedman, Laura A Rodriguez, Marcus A Hoof, Robert H Drury, Jacob T Packer

J Trauma Acute Care Surg· November 2019

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