Publications by authors named "Jacob Sterling"

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Loss of monocyte chemoattractant protein-1 reduced monocyte recruitment and preserved retinal ganglion cells in a mouse model of hypertensive glaucoma.
Michelle Guo, Turner D Schwartz, Emily C N Lawrence, Jingwen Lu, Anny Zhong, Jacob K Sterling

Exp Eye Res· May 2025

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Retinal perivascular macrophages regulate immune cell infiltration during neuroinflammation in mouse models of ocular disease.
Jacob K Sterling, Amrita Rajesh, Steven Droho, Joyce Gong, Andrew L Wang

J Clin Invest· August 2024

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NR4A1 deletion promotes pro-angiogenic polarization of macrophages derived from classical monocytes in a mouse model of neovascular age-related macular degeneration.
Steven Droho, Andrew P Voigt, Jacob K Sterling, Amrita Rajesh, Kyle S Chan

J Neuroinflammation· October 2023

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Oxidative stress induces lysosomal membrane permeabilization and ceramide accumulation in retinal pigment epithelial cells.
Kevin R Zhang, Connor S R Jankowski, Rayna Marshall, Rohini Nair, Néstor Más Gómez, Jacob Sterling

Dis Model Mech· July 2023

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Topical and systemic GLP-1R agonist administration both rescue retinal ganglion cells in hypertensive glaucoma.
Emily C N Lawrence, Michelle Guo, Turner D Schwartz, Jie Wu, Jingwen Lu, Jacob K Sterling

Front Cell Neurosci· June 2023

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Glucagon-like peptide 1 receptor agonist use is associated with reduced risk for glaucoma.
Jacob Sterling, Peiying Hua, Joshua L Dunaief, Qi N Cui, Brian L VanderBeek

Br J Ophthalmol· February 2023

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Inflammatory adipose activates a nutritional immunity pathway leading to retinal dysfunction.
Jacob K Sterling, Bailey Baumann, Sierra Foshe, Andrew Voigt, Samyuktha Guttha

Cell Rep· June 2022

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Minimal effect of conditional ferroportin KO in the neural retina implicates ferrous iron in retinal iron overload and degeneration.
Yingrui Liu, Bailey Baumann, Ying Song, Kevin Zhang, Jacob K Sterling

Exp Eye Res· May 2022

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Conditional knockout of hephaestin in the neural retina disrupts retinal iron homeostasis.
Kevin R Zhang, Bailey Baumann, Ying Song, Jacob Sterling, Elizabeth A Erler

Exp Eye Res· May 2022

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Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein.
Jacob K Sterling, Tae-In Kam, Samyuktha Guttha, Hyejin Park, Bailey Baumann

Cell Rep· February 2022

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Intraocular iron injection induces oxidative stress followed by elements of geographic atrophy and sympathetic ophthalmia.
Yingrui Liu, Brent A Bell, Ying Song, Hye J Kim, Jacob K Sterling

Aging Cell· November 2021

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GLP-1 Receptor Agonist NLY01 Reduces Retinal Inflammation and Neuron Death Secondary to Ocular Hypertension.
Jacob K Sterling, Modupe O Adetunji, Samyuktha Guttha, Albert R Bargoud, Katherine E Uyhazi

Cell Rep· November 2020

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Liver-Specific, but Not Retina-Specific, Hepcidin Knockout Causes Retinal Iron Accumulation and Degeneration.
Bailey H Baumann, Wanting Shu, Ying Song, Jacob Sterling, Zbynek Kozmik

Am J Pathol· September 2019

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Complement C5a receptor knockout has diminished light-induced microglia/macrophage retinal migration.
Delu Song, Michael E Sulewski, Chenguang Wang, Jiantao Song, Rupak Bhuyan, Jacob Sterling

Mol Vis· January 2018

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Conditional Müller Cell Ablation Leads to Retinal Iron Accumulation.
Bailey Baumann, Jacob Sterling, Ying Song, Delu Song, Marcus Fruttiger

Invest Ophthalmol Vis Sci· August 2017

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Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels.
Jacob Sterling, Samyuktha Guttha, Ying Song, Delu Song, Majda Hadziahmetovic

Exp Eye Res· February 2017

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Mice with hepcidin-resistant ferroportin accumulate iron in the retina.
Milan Theurl, Delu Song, Esther Clark, Jacob Sterling, Steve Grieco

FASEB J· February 2016

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