Publications by authors named "Jacob W Howe"

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Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusions.
Anna C Stoll, Christopher J Kemp, Joseph R Patterson, Jacob W Howe, Kathy Steece-Collier

Neurobiol Dis· February 2024

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Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils.
Joseph R Patterson, Joseph Kochmanski, Anna C Stoll, Michael Kubik, Christopher J Kemp, Jacob W Howe

NPJ Parkinsons Dis· January 2024

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Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein.
Joseph R Patterson, Warren D Hirst, Jacob W Howe, Christopher P Russell, Allyson Cole-Strauss

NPJ Parkinsons Dis· May 2022

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Preformed fibrils generated from mouse alpha-synuclein produce more inclusion pathology in rats than fibrils generated from rat alpha-synuclein.
Jacob W Howe, Caryl E Sortwell, Megan F Duffy, Christopher J Kemp, Christopher P Russell

Parkinsonism Relat Disord· August 2021

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Striatal Afferent BDNF Is Disrupted by Synucleinopathy and Partially Restored by STN DBS.
Kathryn M Miller, Joseph R Patterson, Joseph Kochmanski, Christopher J Kemp, Anna C Stoll, Jacob W Howe

J Neurosci· March 2021

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Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils.
Joseph R Patterson, Megan F Duffy, Christopher J Kemp, Jacob W Howe, Timothy J Collier

Neurobiol Dis· October 2019

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Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
Megan F Duffy, Timothy J Collier, Joseph R Patterson, Christopher J Kemp, Kelvin C Luk, Jacob W Howe

J Neuroinflammation· May 2018

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Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
Megan F Duffy, Timothy J Collier, Joseph R Patterson, Christopher J Kemp, Kelvin C Luk, Jacob W Howe

J Neuroinflammation· May 2018

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